Effects of Rho Kinase Inhibitors on Intraocular Pressure and Aqueous Humor Dynamics in Nonhuman Primates and Rabbits [0.03%]
Rho激酶抑制剂对非人灵长类和兔眼压及房水动力学的影响研究
Carol B Toris,Marsha A McLaughlin,Douglas P Dworak et al.
Carol B Toris et al.
Purpose: This study examines the effects of 2 Rho kinase inhibitors on intraocular pressure (IOP) and aqueous humor dynamics. Methods: ...
Effect on Gel Formation Time of Adding Topical Ophthalmic Medications to ReSure Sealant, an In Situ Hydrogel [0.03%]
滴眼液对ReSure密封剂原位水凝胶形成时间的影响研究
Francis S Mah
Francis S Mah
Purpose: The purpose of this study was to describe the gel formation times of ReSure(®) Sealant, an in situ hydrogel approved to seal cataract surgery incisions, when commercially available topical medications are mixed ...
Regenerating Perfection [0.03%]
重塑完美
Dennis O Clegg
Dennis O Clegg
Factors Predictive of Visual Outcome 1 Year After Intravitreal Aflibercept Injection for Typical Neovascular Age-Related Macular Degeneration [0.03%]
注射阿柏西普一年后典型新生血管年龄相关性黄斑变化的视力预后因素分析
Wataru Kikushima,Yoichi Sakurada,Atsushi Sugiyama et al.
Wataru Kikushima et al.
Purpose: Several factors have been reported to be associated with visual outcomes after intravitreal ranibizumab treatment for neovascular age-related macular degeneration (AMD). In the present study, we investigated the ...
Automated Measurement of Cobblestone Morphology for Characterizing Stem Cell Derived Retinal Pigment Epithelial Cell Cultures [0.03%]
用于表征干细胞衍生的视网膜色素上皮细胞培养物的砾石形态自动化测量
Rohini Joshi,Walter Mankowski,Mark Winter et al.
Rohini Joshi et al.
Purpose: Assessing the morphologic properties of cells in microscopy images is an important task to evaluate cell health, identity, and purity. Typically, subjective visual assessments are accomplished by an experienced r...
Hongmin Yun,Yi Zhou,Andrew Wills et al.
Hongmin Yun et al.
Intraocular pressure (IOP) is still the main treatment target for glaucoma. Outflow resistance mainly exists at the trabecular meshwork (TM) outflow pathway, which is responsible for IOP regulation. Changes of TM cellularity and TM extracel...
Induced Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium: A Comparative Study Between Cell Lines and Differentiation Methods [0.03%]
诱导多能干细胞来源的视网膜色素上皮细胞：系间差异及分化方法比较
Lyndsay L Leach,Roxanne H Croze,Qirui Hu et al.
Lyndsay L Leach et al.
Purpose: The application of induced pluripotent stem cell-derived retinal pigmented epithelium (iPSC-RPE) in patients with retinal degenerative disease is making headway toward the clinic, with clinical trials already und...
Human RPE Stem Cell-Derived RPE Preserves Photoreceptors in the Royal College of Surgeons Rat: Method for Quantifying the Area of Photoreceptor Sparing [0.03%]
人源RPE干细胞衍生的RPE可保护皇家外科医学院 rats的光感受器：评估视网膜色素上皮细胞移植保存光感受器面积的方法学研究
Richard J Davis,Timothy A Blenkinsop,Melissa Campbell et al.
Richard J Davis et al.
Purpose: Numerous preclinical studies have shown that transplantation of stem cell-derived retinal pigment epithelial cell (RPE) preserves photoreceptor cell anatomy in the dystrophic Royal College of Surgeons (RCS) rat. ...
An Exploratory Microdialysis Study to Assess the Ocular Pharmacokinetics of Ciprofloxacin Eye Drops in Rabbits [0.03%]
用于评估环丙沙星滴眼液兔眼部药代动力学的探索性微透析研究
Robert Klaus,Chen Jin,Alexandra Maier-Salamon et al.
Robert Klaus et al.
Purpose: Despite the high frequency of use, data regarding the ocular in vivo pharmacokinetics (PK) of topically applied antibiotics are sparse. This study seeks to investigate the PK of the widely used fluoroquinolone ci...