Haiping Yu,Weiwei Chu,Yunquan Zheng et al.
Haiping Yu et al.
The causal relationship between inflammatory factors and acute pancreatitis (AP), chronic pancreatitis (CP), alcohol-induced acute pancreatitis (AAP), and alcohol-induced chronic pancreatitis (ACP) remains unclear. We aimed to examine the c...
Embryonic Lethal Abnormal Visual-Like Protein 1 Aggravates Caerulein-Induced AR42J Cell Injury and Macrophage M1 Polarization to Accelerate Acute Pancreatitis by Upregulating TRAF6 [0.03%]
胚胎致死性异常视觉类似蛋白1通过上调TRAF6加重脂多糖诱导的AR42J细胞损伤和巨噬M1极化从而加速急性胰腺炎的发展
Wenyong Zhou,Xin Wang,Bin Yan et al.
Wenyong Zhou et al.
Tumor necrosis factor receptor-associated factor 6 (TRAF6) has been found to promote the progression of acute pancreatitis (AP). However, its underlying molecular mechanisms in AP need to be further revealed. Caerulein-induced AR42J cells w...
Unraveling the Multifaceted Roles of Atypical Chemokine Receptors in Breast Cancer [0.03%]
非典型趋化因子受体在乳腺癌中的多种作用机制探究
Qinan Yin,Yisha Yang,Zhifeng Qu et al.
Qinan Yin et al.
Breast cancer (BC) remains one of the most prevalent and deadly malignancies among women globally. A deeper understanding of the molecular mechanisms driving BC progression and metastasis is essential for the development of effective therap...
Nerve Growth Factor from Pancreatic Cancer Cells Promotes the Cancer Progression by Inducing Nerve Cell-Secreted Interleukin-6 [0.03%]
胰腺癌细胞源神经营养因子通过诱导神经细胞分泌白介素6促进肿瘤进展
Jianbiao Xu,Yun Shang,Tongmin Wang et al.
Jianbiao Xu et al.
Pancreatic cancer (PC) is a cancer with a poor prognosis, and nerve growth factor (NGF) is involved in the pathogenesis of PC within the unknown exact role. Herein, SW1990 cells and PC12 cells were co-cultured using transwell co-culture sys...
The Impact of Chemokine-Like Receptor 1 Gene Knockout on Lipopolysaccharide-Induced Epididymo-Orchitis in Mice [0.03%]
化学引诱素-like受体1基因敲除对脂多糖诱导的小鼠附睾睾丸炎的影响
Zhonglin Xiao,Jie Chen,Xiujun Fan et al.
Zhonglin Xiao et al.
This comprehensive study delved into the pivotal function of chemokine-like receptor 1 (CMKLR1) in lipopolysaccharide (LPS)-triggered epididymo-orchitis in mice. Upon LPS exposure, wild-type (WT) mice exhibited marked elevations in serum pr...
Overview of Immunological Response in Urological Membranous Nephropathy: Focus on Cytokine and Treatment Options [0.03%]
泌尿系膜性肾病的免疫反应概览：细胞因子和治疗选择:focus
Chao Luo,Chengcheng Wei,Zhaoxian He et al.
Chao Luo et al.
Membranous nephropathy (MN) is an autoimmune disease that is caused by the production of autoantibody against glomerular podocyte antigens by immune cells due to the lack of self-tolerance mechanisms. Similar to many autoimmune diseases, th...
Association of the Single Nucleotide Polymorphism 19216T/C in the TLR2 Gene (rs3804099) with Entamoeba histolytica/Entamoeba dispar/Entamoeba moshkovskii Infection Among Lebanese Children [0.03%]
TLR2基因单核苷酸多态性19216T/C（rs3804099）与黎巴嫩儿童内阿美巴感染的相关性研究
Israa Dib,Hiba Noureddine,Mohamad Fakih et al.
Israa Dib et al.
Toll-like receptors (TLRs), particularly the TLR2, take part in the elicitation of immune responses against Entamoeba histolytica. This study aimed to investigate the relationship between a specific polymorphism called rs3804099 in the TLR2...
David L Woodland
David L Woodland
Multifarious Aspect of Cytokines as an Immuno-Therapeutic for Various Diseases [0.03%]
细胞因子作为多种疾病的免疫治疗的多面性作用
Yash Sharma,Kumud Bala
Yash Sharma
Cytokines are known to be a group of growing small proteins that are majorly responsible for the transmission of signals and communication between hematopoietic cells, the cells of the human immune system, and other types of cells. Cytokine...
IL-4 Downregulates PD-L1 Level Via SOCS1 Upregulation-Induced JNK Deactivation to Enhance Antitumor Immunity in In Vitro Colorectal Cancer [0.03%]
白细胞介素4通过上调SOCS1诱导JNK失活下调PD-L1水平以增强体外结直肠癌抗肿瘤免疫反应
Ruiyan Huang,Baofan Zhang,Wanchun Ye et al.
Ruiyan Huang et al.
Interleukin-4 (IL-4) controls cell growth and immune system regulation in tumorigenesis and can inhibit the growth of colon cancer cell lines, but the possible mechanism is unclear. In this study, we investigated the possible mechanism of I...