Leukemia Inhibitory Factor Receptor Suppresses the Metastasis of Clear Cell Renal Cell Carcinoma Through Negative Regulation of the Yes-Associated Protein [0.03%]
白血病抑制因子受体通过负向调节YES相关蛋白抑制透明细胞肾细胞癌的转移
Chengyong Lei,Shidong Lv,Hongyi Wang et al.
Chengyong Lei et al.
The role of leukemia inhibitory factor receptor (LIFR), which is important in the signal transduction of the interleukin-6 cytokine family, is still undefined in clear cell renal cell carcinoma (ccRCC). Thus, we examined the function and me...
Nidhi Kaushik,Saumya Anang,Krishna Priya Ganti et al.
Nidhi Kaushik et al.
Hepatitis E virus (HEV) is a major cause of viral hepatitis worldwide. Owing to its feco oral transmission route, sporadic as well as epidemic outbreaks recurrently occur. No specific antiviral therapy is available against the disease cause...
Genetic Variation in the H19-IGF2 Cluster Might Confer Risk of Developing Impaired Renal Function [0.03%]
H19-IGF2基因簇的遗传多态性与肾功能损害易感性的关联研究
Eliecer Coto,Carmen Díaz Corte,Salvador Tranche et al.
Eliecer Coto et al.
The H19-IGF2 imprinted gene region could be implicated in the risk of developing impaired renal function (IRF). Our aim was to determine the association of several common H19-IGF2 variants and IRF in a cohort of elderly healthy individuals....
Association Between Four Polymorphisms in lncRNA and Risk of Lung Cancer in a Chinese Never-Smoking Female Population [0.03%]
四种长链非编码RNA多态性与从不吸烟中国女性肺腺癌发病风险相关性研究
Min Gao,Hang Li,Xiaoting Lv et al.
Min Gao et al.
Long noncoding RNAs (lncRNAs) play important roles in the development of human cancers. This is the first case-control study of the association between specific polymorphisms in lncRNA genes and the risk of lung cancer, as well as the gene-...
Rs2303428 of MSH2 Is Associated with Hepatocellular Carcinoma Prognosis in a Chinese Population [0.03%]
MSH2基因的rs2303428多态性与我国肝细胞癌患者预后相关性研究
Xiaonian Zhu,Zhigang Wang,Xiaoqiang Qiu et al.
Xiaonian Zhu et al.
The defects of DNA repair genes may lead to genomic instability and cancer. As an important DNA mismatch repair gene that maintains genomic stability from DNA replication errors, genetic variants of mutS homolog 2 (MSH2) are associated with...
Enteric Neural Stem Cells Expressing Insulin-Like Growth Factor 1: A Novel Cellular Therapy for Hirschsprung's Disease in Mouse Model [0.03%]
表达胰岛素样生长因子1的肠神经干细胞：在小鼠模型中治疗先天性巨结肠病的新细胞疗法
Wei Liu,Lijuan Zhang,Rongde Wu
Wei Liu
Transplanting enteric neural stem cells (ENSCs) is an innovative approach for replacing enteric neurons in Hirschsprung's disease (HSCR). However, posttransplantation cell survival and differentiation limit efficacy. We aimed to investigate...
ARG1 Gene Polymorphisms and Their Association in Individuals with Essential Hypertension: A Case-Control Study [0.03%]
中国原发性高血压患者EGR1基因多态性及其与疾病的关联研究
Syed Fawad Ali Shah,Tahir Iqbal,Raheel Qamar et al.
Syed Fawad Ali Shah et al.
The purpose of this study is to investigate the association of variant alleles (rs2781666 and rs2781667) at ARG1 to be involved in the generation of essential hypertension (EH) phenotypes in human subjects. The ARG1 noncoding polymorphisms ...
Jingyi Yuan,Jiali Zeng,Chun Shuai et al.
Jingyi Yuan et al.
Gastric cancer has a high incidence and mortality in the world, especially in China. The pathogenesis leading to the high heterogeneity of gastric cancer remains unclear. It is believed that TWSG1 is associated with a variety of tumors, but...
The Critical, Clinical Role of Interferon-Beta in Regulating Cancer Stem Cell Properties in Triple-Negative Breast Cancer [0.03%]
干扰素-β在调节三阴性乳腺癌干细胞特性中的关键临床作用
Mary R Doherty,Mark W Jackson
Mary R Doherty
Triple-negative breast cancer (TNBC) the deadliest form of this disease currently lacks a targeted therapy and is characterized by increased risk of metastasis and presence of therapeutically resistant cancer stem cells (CSC). Recent eviden...
Toxic Effect of Cadmium, Lead, and Arsenic on the Sertoli Cell: Mechanisms of Damage Involved [0.03%]
镉、铅和砷对支持细胞的毒性作用及所涉及的损伤机制
Juan Ramos-Treviño,Susana Bassol-Mayagoitia,José Anselmo Hernández-Ibarra et al.
Juan Ramos-Treviño et al.
Over the past decades, an increase has been described in exposure to environmental toxins; consequently, a series of studies has been carried out with the aim of identifying problems associated with health. One of the main risk factors is e...