Molecular and Histopathology Diagnosis of Human Tegumentary Leishmaniasis Using Glycol Methacrylate-Embedded Samples: A New Approach for Referral Centers [0.03%]
采用甘氧甲基丙烯酸酯包埋切片进行分子及组织病理诊断美洲型利什曼病是一项适用于参考实验室的新方法研究
Cintia Xavier de Mello,Abraão Dornellas,Tatiana Queiroz et al.
Cintia Xavier de Mello et al.
Tegumentary leishmaniasis (TL) is a neglected tropical disease that affects approximately one million new patients living in endemic areas with a lack of health service infrastructure. In many countries, including Brazil, public referral ce...
Extracellular Vesicle-Liposome Hybrid Nanoparticles Delivery of CRISPR/Cas9 Induces a Unique DNA Repair Pattern in the HGF Gene of Stem Cells from Apical Papilla [0.03%]
外泌体-脂质体杂合纳米粒子递送CRISPR / Cas9诱导牙乳头干细胞HGF基因产生独特的DNA修复模式
Razieh Yazdani,Mohammad Hossein Nasr Esfahani,Shahin Eghbalsaied et al.
Razieh Yazdani et al.
Extracellular vesicles (EVs) have been investigated due to their natural biocompatibility and targeting capabilities. The specific approach of combining EVs with liposomes to create hybrid nanoparticles (ELNPs) for the delivery of the clust...
New Perspectives on Paracrine IL-18 Signaling in the Intestinal Epithelium [0.03%]
肠上皮细胞旁IL-18信号的新视角
Nathaniel J Winsor,Adrienne Ranger,Ojas Singh et al.
Nathaniel J Winsor et al.
IL-18 is a member of the IL-1 family of cytokines, which is highly expressed in intestinal epithelial cells (IECs). Upon barrier breach, IL-18 is matured to its bioactive form as a result of inflammasome activation, released from the cell v...
Autophagy and Reactive Oxygen Species in Megakaryopoiesis and Platelet Production [0.03%]
巨核细胞生成和血小板产生的自噬和活性氧物种
Abbas Khosravi,Abtin Ghasempour,Mostafa Paridar et al.
Abbas Khosravi et al.
Megakaryocytes (MKs), which are differentiated from megakaryocytic-erythrocytic progenitors, generate platelets (PLTs) by expanding and branching their cellular fragments under the influence of cytokines and intercellular mechanisms such as...
Decoding Noncoding RNAs: Mastering Bone Morphogenetic Protein Signaling and Crosstalk Pathways for Breakthroughs in Periodontal Regeneration [0.03%]
破译非编码RNA：掌握骨形态发生蛋白信号传导和串扰途径以实现牙周再生的突破
Hamed Ghanati,Salar Motamedi,Shila Fallahpour et al.
Hamed Ghanati et al.
Regenerating periodontal tissues remains a significant hurdle in regenerative dentistry, requiring meticulous coordination of cellular and molecular mechanisms. Noncoding RNAs (ncRNAs), including microRNAs, long ncRNAs, and circular RNAs, a...
Ovine TUSC5 and IGFBP3 Gene Polymorphisms and their Association with Tail Fat Weight in Sheep [0.03%]
卵泡刺激素受体基因多态性与牛繁殖性能的关系研究
Peiliang Cao,Deyin Zhang,Dan Xu et al.
Peiliang Cao et al.
Tail fat weight is a key economic trait in fat-tailed sheep; reducing tail fat deposition is of significant importance for improving the economic efficiency of sheep farming. In this article, we measured the live weight before slaughter, ta...
Bile Acid-Mediated Interactions with Various Cell Types in the Cholestatic Liver [0.03%]
胆汁淤积性肝病时胆酸与各种细胞类型的相互作用
Guanyi He,Jie Qing
Guanyi He
Bile acids (BAs) have garnered significant attention due to their novel roles in modulating diverse host physiological processes. They play a crucial role in nutrient transport, organelle function, and maintaining the systemic balance of pr...
Effect of Licorice (Glycyrrhiza glabra)-Silver Nanoparticles on Liver and Kidney Histopathological Features in Common Carp Fish (Cyprinus carpio) [0.03%]
甘草(S Glycyrrhizae)-银纳米颗粒对鲤鱼(Cyrpinus carpio)肝、肾组织病理学特征的影响
Hawre K Faraj,Nasreen M Abdulrahman
Hawre K Faraj
The increasing use of silver nanoparticles (AgNPs) in aquaculture has raised concerns regarding their potential toxic effects on fish health, particularly on vital organs, such as the liver and kidneys. Licorice (Glycyrrhiza glabra) root, k...
Exosome-Mediated circRNA Hsa_Circ_0113050 Enhances Colorectal Cancer Cell Malignancy by Interacting with EIF4A3 [0.03%]
circRNA Hsa_Circ_0113050通过与EIF4A3互作促进结直肠癌细胞恶性表型的外泌体介导机制研究
Yuan Tian,Chen He
Yuan Tian
The exosome-mediated circular RNAs (circRNAs) play a crucial role in tumorigenesis. The present study investigated the role of the exosome-mediated circRNA hsa_circ_0113050 in colorectal cancer (CRC) through its interaction with the eukaryo...