Association Between Polymorphisms in DNA Damage Repair Pathway Genes and Female Breast Cancer Risk [0.03%]
DNA修复通路基因多态性与女性乳腺癌发病风险的关系研究
Ying Wang,Yalan Sun,Mingjuan Tan et al.
Ying Wang et al.
Breast cancer risk have been discussed to be associated with polymorphisms in genes as well as abnormal DNA damage repair function. This study aims to assess the relationship between genes single nucleotide polymorphisms (SNPs) related to D...
Chang Sun,Shanshan Zhao,Zimeng Pan et al.
Chang Sun et al.
Polycystic ovary syndrome (PCOS) refers to an endocrine disorder syndrome that are correlated with multiple organs and systems. PCOS has an effect on women at all stages of their lives, and it has an incidence nearly ranging from 6% to 20% ...
Anti-Inflammatory Effects of Glucagon-Like Peptide-1 Receptor Agonists via the Neuroimmune Axis [0.03%]
肠促胰素-1受体激动剂通过神经免疫轴发挥抗炎作用
Susanna Fang,Chi Kin Wong
Susanna Fang
Glucagon-like peptide 1 receptor agonists (GLP-1RAs) have shown efficacy in the treatment of metabolic disease-related complications, partially attributable to their anti-inflammatory properties. However, the specific cell types and pathway...
EIF4A3-Bound hsa_circ_0006847 Exerts a Tumor-Suppressive Role in Gastric Cancer [0.03%]
胃癌中EIF4A3结合的hsa_circ_0006847发挥肿瘤抑制作用
Chunli Cao,Xinxin Wu,Zhe Li et al.
Chunli Cao et al.
Numerous studies have shown that circular RNAs are associated with the occurrence and development of various cancers, but the biological functions and mechanisms of hsa_circ_0006847 (circASPHD1) in gastric cancer (GC) remain unclear. The ex...
Circ-EIF3I Promotes Hepatocellular Carcinoma Progression Through Modulating miR-361-3p/DUSP2 Axis [0.03%]
circ-EIF3I通过调控miR-361-3p/DUSP2轴促进肝癌进展
Lingna Ni,Qianqian Gao,Qiu Zhao et al.
Lingna Ni et al.
Hepatocellular carcinoma (HCC) is one of the most common malignant cancers globally. Circular RNAs (circRNAs) have been implicated in the development of HCC. Previous studies have confirmed that circ-EIF3I plays an important role in the pro...
microRNA-141-3p Suppressed the Progression of the Clear Cell Renal Cell Carcinoma by Targeting Transforming Growth Factor Beta 2 Gene Expression [0.03%]
微小核糖核酸-141-3p通过靶向转化生长因子β2基因表达抑制透明细胞肾细胞癌的进展
Xinming Hu,Desheng Li,Jiangtao Zhan et al.
Xinming Hu et al.
Clear cell renal cell carcinoma (ccRCC) is a malignant tumor of kidney epithelial cells, one of the most common tumors in the world. Transforming growth factor beta (TGFβ)1 is a crucial factor that induces epithelial-mesenchymal transition...
Angiopoietin-Related Protein 4-Transcript 3 Increases the Proliferation, Invasion, and Migration of Hepatocellular Carcinoma Cells and Inhibits Apoptosis [0.03%]
血管生成素相关蛋白4-转录本3促进肝癌细胞的增殖、侵袭和迁移，并抑制其凋亡
Yun Bai,Guanghua Cui,Xiaoke Sun et al.
Yun Bai et al.
To investigate the functional differences of angiopoietin-related protein 4 (ANGPTL4) transcripts in hepatocellular carcinoma (HCC) cells. By transfecting ANGPTL4-Transcript 1 and ANGPTL4-Transcript 3 overexpression vectors into HepG2 and H...
Tanshinone I Stimulates Pyroptosis of Cisplatin-Resistant Gastric Cancer Cells by Activating the NF-κB/Caspase-3(8)/GSDME Signaling Pathway [0.03%]
丹参酮I通过激活NF-κB/Caspase-3(8)/GSDME信号通路刺激顺铂耐药胃癌细胞发生焦亡
Guijun Wang,Yanrong Li,Zhaokai Guo et al.
Guijun Wang et al.
Cisplatin (DDP) resistance frequently occurs in gastric cancer (GC) therapy. Tanshinone I is a liposoluble phenanthraquinone compound present in the roots of Salvia miltiorrhiza Bunge (Danshen). In this study, we aimed to explore the effect...
IFI16 Positively Regulates RIG-I-Mediated Type I Interferon Production in a STING-Independent Manner [0.03%]
IFI16正向调节RIG-I介导的I型干扰素产生作用不依赖STING存在
Xibao Shi,Menglu Wei,Yuwen Feng et al.
Xibao Shi et al.
Previous studies have shown that interferon gene-stimulating protein (STING) is essential for IFN-γ-inducible protein 16 (IFI16) as the DNA sensor and RNA sensor to induce transcription of type I interferon (IFN-I) and is essential for IFI...
Sedigheh Bahmyari,Seyyed Hossein Khatami,Sina Taghvimi et al.
Sedigheh Bahmyari et al.
Around 50% of all occurrences of infertility are attributable to the male factor, which is a significant global public health concern. There are numerous circumstances that might interfere with spermatogenesis and cause the body to produce ...