Reg3A Overexpression Facilitates Hepatic Metastasis by Altering Cell Adhesion in LoVo Colon Cancer Cells [0.03%]
REG家族成员Reg3A促进结肠癌肝内转移作用及机制研究
Ke-Yi Xu,Mao Li,Wei-Hong Yu et al.
Ke-Yi Xu et al.
Guangyuan Li,Nathan Salomonis
Guangyuan Li
While immunotherapy is typically reserved for cancer patients with a high mutational burden, neoantigens produced from post-transcriptional regulation provide a possible untapped reservoir of common immunogenic targets for new targeted canc...
A de novo Mutation (p.Gln277X) of Cyclin D2 is Responsible for a Child with Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome [0.03%]
CCND2新发突变(p.Gln277X)导致的巨脑-多小脑回-多指(趾)-脑积水综合征患儿报告
Mei-Fang Zhao,Song-Lin Zhang,YangZiYu Xiang et al.
Mei-Fang Zhao et al.
Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH), a type of overgrowth syndrome, is characterized by progressive megalencephaly, cortical brain malformations, and distal limb anomalies. Previous studies have revealed ...
Case Reports
DNA and cell biology. 2024 Jul;43(7):325-330. DOI:10.1089/dna.2023.0391 2024
Major Facilitator Superfamily Domain Containing 12 Is Overexpressed in Lung Cancer and Exhibits an Oncogenic Role in Lung Adenocarcinoma Cells [0.03%]
肺癌中主要 facilitator 超家族结构域含 12 基因过表达及其在肺腺癌细胞中的致癌作用
Weijun Zhao,Xilin Hu,Zixuan Chen et al.
Weijun Zhao et al.
Major facilitator superfamily domain containing 12 (MFSD12) regulates lysosomal cysteine import and promotes the proliferation and survival of melanoma cells. However, the expression and function of MFSD12 in other cancers, particularly in ...
FOXO1 Single-Nucleotide Polymorphisms Are Associated with Bleeding Severity and Sensitivity of Glucocorticoid Treatment of Pediatric Immune Thrombocytopenia [0.03%]
FOXO1单核苷酸多态性与儿童免疫性血小板减少症的出血严重程度及糖皮质激素治疗敏感性的关联研究
Xingjuan Xie,Hao Gu,Jingyao Ma et al.
Xingjuan Xie et al.
Immune thrombocytopenia (ITP) is an autoimmune-mediated hemorrhagic disease. Emerging evidence indicates that FOXO1 SNPs are related to the immune dysregulation of several autoimmune diseases suggesting that FOXO1 may be involved in inflamm...
Zymolyase Treatment of Saccharomyces cerevisiae Affects Cellular Proteins and Degrades Tyrosyl-DNA Phosphodiesterase I [0.03%]
佐霉酶处理影响酿酒酵母的细胞蛋白并降解酪氨酰-DNA磷双酯酶I
Evan J Brettrager,Aaron J Frederick,Robert C A M van Waardenburg
Evan J Brettrager
Saccharomyces cerevisiae is a genetically tractable, affordable, and extensively documented eukaryotic single-cell model organism. This budding yeast is amenable for the development of genetic and biochemical experiments and is frequently u...
Bone Remodeling and Bone Structural Genes in Legg-Calvé-Perthes Disease: The OPG rs2073618 and IL-6 rs1800795 Are Associated with High Risk in Mexican Patients [0.03%]
Legg-Calvé-Perthes病的骨重建和骨结构基因：OPG rs2073618 和IL-6rs1800795位点与墨西哥患者的高风险相关
Blanca Lucía Cruz-Ortíz,Edgar Hernández-Zamora,Elba Reyes-Maldonado et al.
Blanca Lucía Cruz-Ortíz et al.
Legg-Calve-Perthes disease (LCPD) is an idiopathic avascular necrosis of the pediatric femoral head. Bone remodeling and bone structural genes have the potential to contribute to the progression of LCPD when there is disequilibrium between ...
PANoptosis Features, a Humanized NSG Murine Model of Sjogren's Syndrome [0.03%]
PANoptosis特征及Sjögren综合征人源化NSG小鼠模型
Yiying Yang,Huali Zhang,Xiaoyu Xiao et al.
Yiying Yang et al.
Sjogren's syndrome (SS) is a complex systemic autoimmune disease. This study aims to elucidate a humanized NOD-PrkdcscidIl2rgem1/Smoc (NSG) murine model to better clarify the pathogenesis of SS. NSG female mice were adoptively transferred w...
m6A RNA Methylation and Implications for Hepatic Lipid Metabolism [0.03%]
N6-甲基腺苷（m6A）RNA甲基化与肝脏脂质代谢关系的研究进展
Xinyue Ming,Shirui Chen,Huijuan Li et al.
Xinyue Ming et al.
This review presents a summary of recent progress in research on the N6-methyladenosine (m6A) modification and regulatory roles in hepatic lipid metabolism. As the most abundant internal modification of eukaryotic RNA, the m6A modification ...
Evaluation of Tumorigenic Properties of MDA-MB-231 Cancer Stem Cells Cocultured with Telocytes and Telocyte-Derived Mitochondria Following miR-146a Inhibition [0.03%]
抑制miR-146a后与TEL细胞和TEL线粒体共培养的MDA-MB-231癌干细胞致瘤性的评价研究
Sena Babadag,Özlem Altundag-Erdogan,Yeliz Z Akkaya-Ulum et al.
Sena Babadag et al.
Telocytes have some cytoplasmic extensions called telopodes, which are thought to play a role in mitochondrial transfer in intercellular communication. Besides, it is hypothesized that telocytes establish cell membrane-mediated connections ...