Sepideh Sarfi,Ehsaneh Azaryan,Mohsen Naseri
Sepideh Sarfi
Teeth are vulnerable to structural compromise, primarily attributed to carious lesions, in which microorganisms originating from the oral cavity deteriorate the mineralized structures of enamel and dentin, subsequently infiltrating the unde...
Wei Li,Yongjian Hao
Wei Li
Polo-like kinase 1 (Plk1), an evolutionarily conserved serine/threonine protein kinase, is a key regulator involved in the mitotic process of the cell cycle. Mounting evidence suggests that Plk1 is also involved in a variety of nonmitotic e...
Sabrina N Kline,Yoshine Saito,Nathan K Archer
Sabrina N Kline
Skin homeostasis relies on a delicate balance between host proteases and protease inhibitors along with those secreted from microbial communities, as disruption to this harmony contributes to the pathogenesis of inflammatory skin disorders,...
The Cardiovascular Benefits of Glucagon-Like Peptide-1 Receptor Agonists as Novel Diabetes Drugs Are Mediated via the Suppression of miR-203a-3p and miR-429 Expression [0.03%]
肠促胰素受体激动剂通过抑制miR-203a-3p和miR-429表达介导心血管益处：新型降糖药物的研究进展
Yanfen Liu,Dongying Nie,Xueyong Lou
Yanfen Liu
Coronary artery disease (CAD) is associated with a high fatality rate and a heavy global health care burden. Glucagon-like peptide-1 (GLP-1) exerts positive cardiovascular effects, although the molecular mechanisms are unclear. Therefore, t...
Low and High-Normal FMR1 Triplet Cytosine, Guanine Guanine Repeats Affect Ovarian Reserve and Fertility in Women Who Underwent In Vitro Fertilization Treatment? Results from a Cross-Sectional Study [0.03%]
低和高正常的FMR1三联核苷酸胞嘧啶、鸟嘌呤、鸟嘌呤重复序列影响体外受精治疗妇女的卵巢储备和生育力吗？来自一项横断面研究的结果
Ana Carolina Vasconcelos Nunes,Camila Martins Trevisan,Carla Peluso et al.
Ana Carolina Vasconcelos Nunes et al.
Dynamic mutations in the 5' untranslated region of FMR1 are associated with infertility. Premutation alleles interfere with prenatal development and increase infertility risks. The number of CGG repeats that causes the highest decrease in o...
Plabita Paul,Bandita Nayak,Satish Mishra
Plabita Paul
Plasmodium parasites, the causative agents of malaria, rely on sophisticated cellular mechanisms to survive and proliferate within their hosts. Plasmodium complex life cycle requires posttranslational modifications (PTMs) to control cellula...
Shen-Qi-Ling-Bi Decoction Inhibits Colorectal Cancer Cell Growth by Inducing Ferroptosis Through Inactivation of PI3K/AKT Signaling Pathway [0.03%]
参七灵壁汤通过抑制PI3K/AKT信号通路诱导 colorectal cancer 细胞铁死亡阻止肿瘤增殖
Lin Liu,Guanlong Ye,Wei Huang et al.
Lin Liu et al.
Colorectal cancer (CRC) is a common malignancy with poor prognosis. Shen-Qi-Ling-Bi Decoction (SQLB), a classic traditional Chinese medicine (TCM) formula, was found to exert antitumor effects in CRC. This study aimed to explore the biologi...
Investigating the Effects of AL049796.1 Silencing in Inhibiting High Glucose-Induced Colorectal Cancer Progression [0.03%]
探究AL049796.1沉默对高糖诱导的结直肠癌进展抑制作用的影响
Yan Liu,Qi Wang,Zicheng Sun et al.
Yan Liu et al.
Patients with colorectal cancer (CRC) and diabetes share many risk factors. Despite a strong association between diabetes and CRC being widely studied and confirmed, further genetic research is needed. This study found higher AL049796.1 and...
ANGPTL4 Stabilizes Bone Morphogenetic Protein 7 Through Deubiquitination and Promotes HCC Proliferation via the SMAD/MAPK Pathway [0.03%]
ANGPTL4通过去泛素化稳定骨形态发生蛋白7并通过SMAD/MAPK通路促进肝癌增殖
Yun Bai,Guanghua Cui,Xiaoke Sun et al.
Yun Bai et al.
This study aimed to determine the function of angiopoietin-related protein 4 (ANGPTL4) and bone morphogenetic protein 7 (BMP7) on hepatocellular carcinoma (HCC). Overexpressing plasmids were cotransfected into HepG2 cells to determine the i...
Ziyan Pan,Mohammed Eslam
Ziyan Pan
Organ fibrosis is a devastating medical challenge that is collectively responsible for an estimated 45% of all deaths in developed countries and poses a substantial health and economic burden. The process of fibrosis has common characterist...