Exploratory Cohort Study of Depressive Symptoms in South Africans with HIV-1 Subtype C: Associations with Kynurenine Pathway Metabolites and Inflammatory Markers [0.03%]
南非C型HIV感染者抑郁症状的探索性队列研究：与犬尿氨酸途径代谢物和炎症标志物的关系
Monray Edward Williams,Lusilda Schutte,Levanco K Asia et al.
Monray Edward Williams et al.
Correction: PKR Inhibition Prevents Neuroinflammation and Rescues Depressive‑Like Behaviors Via BDNF/TrkB Signaling [0.03%]
校正：PKR抑制通过BDNF/TrkB信号传导防止神经炎症并挽救类似抑郁的行为
Yue Hu,Tahir Ali,Shengnan Mou et al.
Yue Hu et al.
Repositioning of Alogliptin to Mitigate Secondary Injury Induced by Repetitive TBI: Potential Role of its Antioxidant and Anti- Inflammatory Effects [0.03%]
阿罗格利平重新定位以减轻重复性TBI引起的继发性损伤：其抗氧化和抗炎作用的潜在作用
Hossam A Raslan,Haidy E Michel,Esther T Menze et al.
Hossam A Raslan et al.
Repetitive traumatic brain injury (RTBI) refers to brain injuries resulting from an external mechanical force causing cumulative and frequently severe neurological consequences. This study aimed to explore the neuroprotective effect of alog...
Dexmedetomidine Mitigates Sevoflurane-Induced Neurodevelopmental Effects in Paediatric Anaesthesia: A Meta-Analysis and Preclinical Study [0.03%]
丁丙诺啡减轻小儿麻醉中七氟醚引起的神经发育效应：一项 meta 分析和动物实验研究
Hsuan-Chih Lao,Chia-Wei Huang,Ssu-Han Wang et al.
Hsuan-Chih Lao et al.
Sevoflurane (Sevo) anaesthesia in children is linked to an increased incidence of postoperative emergence agitation (EA) and potential neurotoxicity in developing brains. However, the specific risks of subanaesthetic foetal or neonatal expo...
Gut Microbiome-Sphingolipid Metabolism-Brain Axis Interactions: Neuroprotective Effects of Amitriptyline as Functional Inhibitor of Acid Sphingomyelinase in a Mouse Model of Tauopathy [0.03%]
肠道微生物群-鞘脂代谢-脑轴相互作用：阿米替林作为tau病小鼠模型中酸性鞘磷脂酶功能抑制剂的神经保护效应
Mennatallah Ibrahim,Asmaa M Khalil,Heba Attia et al.
Mennatallah Ibrahim et al.
Tauopathies are neurodegenerative diseases characterized by accumulation of hyperphosphorylated tau protein (P-tau). The gut microbiota (GM) is symbiotic with the host and altered in neurodegenerative diseases. Amitriptyline (AMI) is a func...
Prenatal Interferon-Alpha Exposure Induces Autism-Like Neurobehavioral and Neurochemical Alterations in Male Offspring [0.03%]
宫内接触干扰素诱导子代雄鼠产生自闭症样的神经行为和神经生化改变
Güliz Otkıran,Mümin Alper Erdoğan,Yiğit Uyanıkgil et al.
Güliz Otkıran et al.
Maternal immune activation (MIA) during pregnancy has been implicated as a key environmental risk factor in autism spectrum disorder (ASD). Interferon-alpha (IFN-α), a type I interferon, may disrupt fetal neurodevelopment, yet its mechanis...
Modulation of Cognitive Function by TRPM3 Channels in the Dentate Gyrus of a Menopausal Rat Model: Effects of Naringenin Treatment and Ciliary Neurotrophic Factor [0.03%]
TRPM3通道在绝经大鼠海马齿状回区对认知功能的调节作用：柚皮素干预和神经保护因子的作用效应
Kamini R Shirasath,Kartik T Nakhate,Sameer N Goyal et al.
Kamini R Shirasath et al.
Although transient receptor potential melastatin 3 (TRPM3) channels are primarily known for their role in spinal nociception, emerging evidence suggests their involvement in psychiatric conditions and central reward processing. Menopause, c...
Telitacicept as a New Therapeutic Avenue for Generalized Myasthenia Gravis and Thymoma-Associated Myasthenia Gravis [0.03%]
泰利西替普治疗重症肌无力和胸腺瘤相关重症肌无力的新途径
Ying Zhu,Benqiao Wang,Chunxiang Hu et al.
Ying Zhu et al.
Generalized myasthenia gravis (gMG) is an antibody mediated autoimmune neuromuscular junction disorder characterized by muscle weakness and fatigue as well as acetylcholine receptor antibody (AChR-Ab) as the main presence. A proportion of p...
Histamine H3 Receptor Antagonist, Thioperamide, Improves Behavioral and Neuropathological Changes Associated with Subclinical Hypersensitivity to a Cow's Milk Allergen [0.03%]
组胺H3受体拮抗剂噻operamide改善与亚临床牛乳过敏原敏感性相关的行为和神经病理学改变
Danielle Germundson-Hermanson,Marilyn G Klug,Kumi Nagamoto-Combs
Danielle Germundson-Hermanson
Mood and behavior-related comorbidities are often reported with food allergies, an atopic condition that elevates histamine (HA) levels in tissues and circulation. However, whether allergy-induced HA directly affects the central nervous sys...
Ameliorative Effect of Vitamin C Against Tramadol-Induced Learning and Memory Impairment in Juvenile Rat Via Attenuation of Oxidative Stress and Dysfunctional Synaptic Plasticity [0.03%]
维生素C对曲马多致大鼠学习记忆障碍的改善作用及机理研究
Lily Mohammadipoor-Ghasemabad,Khadijeh Esmaeilpour,Manzumeh Shamsi Meymandi et al.
Lily Mohammadipoor-Ghasemabad et al.
Tramadol (TM) abuse negatively affects the central nervous system, especially brain regions like the hippocampus involved in cognition. Recent studies have demonstrated neuroprotective effects of Vitamin C (Vit C) in various neurological di...