Zayd Farah,Huimin Fan,Zhongmin Liu et al.
Zayd Farah et al.
Correct selection of an appropriate animal mode to closely mimic human extremity diseases or to exhibit desirable phenotypes of limb regeneration is the first critical step for all scientists in biomedical and regenerative researches. The c...
Zograb Makiyan
Zograb Makiyan
Sex assignment in newborns depends on the anatomy of the external genitalia, despite this stage being the final in embryogenesis. According to the current view, the genital tubercle is the embryonic precursor of penis and clitoris. It origi...
Case Reports
Organogenesis. 2016 Oct;12(4):169-182. DOI:10.1080/15476278.2016.1210749 2016
Involvement of IGF-2, IGF-1R, IGF-2R and PTEN in development of human tooth germ - an immunohistochemical study [0.03%]
IGF-2、IGF-1R、IGF-2R和PTEN在人牙胚发生中的作用——免疫组化研究
Darko Kero,Livia Cigic,Ivana Medvedec Mikic et al.
Darko Kero et al.
Insulin-Like Growth Factor 2 (IGF-2) is a peptide hormone essential for prenatal growth and development. IGF-2 exerts its mitogenic effects via Insulin-Like Growth Factor 1 Receptor (IGF-1R), and is eliminated by binding to Insulin-Like Gro...
Mickey Shah,Richard L George,M Michelle Evancho-Chapman et al.
Mickey Shah et al.
Dedifferentiated fat cells show great promises as a novel cell source for stem cell research. It has many advantages when used for cell-based therapeutics including abundance, pluripotency, and safety. However, there are many obstacles rese...
Vitamin C promotes the proliferation of human adipose-derived stem cells via p53-p21 pathway [0.03%]
维生素C通过p53-p21途径促进人脂肪源干细胞的增殖
Peihua Zhang,Jin Li,Yawei Qi et al.
Peihua Zhang et al.
Although adipose-derived stem cells (ADSCs) have demonstrated a promising potential for the applications of cell-based therapy and regenerative medicine, excessive reactive oxygen species (ROS) are harmful to ADSCs cell survival and prolife...
Decellularized spleen matrix for reengineering functional hepatic-like tissue based on bone marrow mesenchymal stem cells [0.03%]
基于骨髓间充质干细胞的肝样组织工程用脱细胞脾基底膜材料的研究
Junxi Xiang,Xinglong Zheng,Peng Liu et al.
Junxi Xiang et al.
Background and aims: Decellularized liver matrix (DLM) hold great potential for reconstructing functional hepatic-like tissue (HLT) based on reseeding of hepatocytes or stem cells, but the shortage of liver donors is stil...
Membrane channel gene expression in human costal and articular chondrocytes [0.03%]
人肋软骨和关节软骨细胞膜通道基因表达差异研究
A Asmar,R Barrett-Jolley,A Werner et al.
A Asmar et al.
Chondrocytes are the uniquely resident cells found in all types of cartilage and key to their function is the ability to respond to mechanical loads with changes of metabolic activity. This mechanotransduction property is, in part, mediated...
The fatty acid chain elongase, Elovl1, is required for kidney and swim bladder development during zebrafish embryogenesis [0.03%]
脂肪酸链延长酶Elovl1在斑马鱼肾和膀胱发育过程中是必需的
Sushil Bhandari,Joon No Lee,Young-Il Kim et al.
Sushil Bhandari et al.
Very long chain fatty acids are required for sphingolipid synthesis, lipid homeostasis, myelin formation, epidermal permeability, and retinal function. Seven different enzymes are known to be involved in the elongation cycle of fatty acids,...
The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes [0.03%]
FGF9及其受体在小鼠睾丸发育过程中的表达谱分析
Meng-Shao Lai,Chia-Yih Wang,Shang-Hsun Yang et al.
Meng-Shao Lai et al.
An expressional lack of fibroblast growth factor 9 (FGF9) would cause male-to-female sex reversal in the mouse, implying the essential role of FGF9 in testicular organogenesis and maturation. However, the temporal expression of FGF9 and its...
Young Hwan Choi,Il Ho Jang,Soon Chul Heo et al.
Young Hwan Choi et al.
WKYMVm hexapeptide has been identified as a strong FPR2 agonist through a library screening of synthetic peptides. The FPR2 has been reported to play a crucial role in inflammation and angiogenic responses via stimulation of chemotaxis, mig...