The epidemiology of supernumerary teeth and the associated molecular mechanism [0.03%]
多余牙的流行病学及其相关的分子机制
Xi Lu,Fang Yu,Junjun Liu et al.
Xi Lu et al.
Supernumerary teeth are common clinical dental anomalies. Although various studies have provided abundant information regarding genes and signaling pathways involved in tooth morphogenesis, which include Wnt, FGF, BMP, and Shh, the molecula...
Enamel matrix derivative enhances the proliferation and osteogenic differentiation of human periodontal ligament stem cells on the titanium implant surface [0.03%]
enamel matrix衍生物可促进人牙周膜干细胞在钛种植体表面的增殖及成骨分化
Guang Li,Jing Hu,Hui Chen et al.
Guang Li et al.
Periodontal ligament stem cells (PDLSCs) have mesenchymal-stem-cells-like qualities, and are considered as one of the candidates of future clinical application in periodontal regeneration therapy. Enamel matrix derivative (EMD) is widely us...
Microenvironment of a tumor-organoid system enhances hepatocellular carcinoma malignancy-related hallmarks [0.03%]
肿瘤类器官系统的微环境增强了肝细胞癌恶性相关的特征
Yang Wang,Kazuki Takeishi,Zhao Li et al.
Yang Wang et al.
Organ-like microenviroment and 3-dimensional (3D) cell culture conformations have been suggested as promising approaches to mimic in a micro-scale a whole organ cellular functions and interactions present in vivo. We have used this approach...
Zograb Makiyan
Zograb Makiyan
Endometriosis is defined by the presence of endometrial ectopia. Multiple hypotheses have been postulated to explain the etiology of endometriosis to understand various clinical evidences. The etiology of endometriosis is still unclear.The ...
Analysis of spatiotemporal pattern and quantification of gastrointestinal slow waves caused by anticholinergic drugs [0.03%]
抗胆碱药物引起胃肠慢波时空模式分析及量化研究
Kelvin K L Wong,Lauren C Y Tang,Jerry Zhou et al.
Kelvin K L Wong et al.
Anticholinergic drugs are well-known to cause adverse effects, such as constipation, but their effects on baseline contractile activity in the gut driven by slow waves is not well established. In a video-based gastrointestinal motility moni...
Comparison of early vascular morphological changes between bioresorbable poly-L-lactic acid scaffolds and metallic stents in porcine iliac arteries [0.03%]
可吸收聚乳酸支架与金属裸支架早期血管内膜增生反应的猪髂动脉模型研究
Yasuhito Sekimoto,Hideaki Obara,Kentaro Matsubara et al.
Yasuhito Sekimoto et al.
Bioresorbable scaffolds have the potential to overcome several problems associated with metallic stents. Bioresorbable poly-L-lactic acid (PLLA) scaffold implantation for the treatment of peripheral artery disease has already been reported ...
Comparative Study
Organogenesis. 2017 Apr 3;13(2):29-38. DOI:10.1080/15476278.2017.1280211 2017
Current strategies to generate mature human induced pluripotent stem cells derived cholangiocytes and future applications [0.03%]
当前用于产生人诱导多能干细胞源成熟胆管上皮细胞的策略及其未来应用展望
Eduardo Cervantes-Alvarez,Yang Wang,Alexandra Collin de lHortet et al.
Eduardo Cervantes-Alvarez et al.
Stem cell research has significantly evolved over the last few years, allowing the differentiation of pluripotent cells into almost any kind of lineage possible. Studies that focus on the liver have considerably taken a leap into this novel...
Recellularization via the bile duct supports functional allogenic and xenogenic cell growth on a decellularized rat liver scaffold [0.03%]
胆管去细胞肝脏支架支持同种异体和异种细胞的再生化生长
Wessam Hassanein,Mehmet C Uluer,John Langford et al.
Wessam Hassanein et al.
Recent years have seen a proliferation of methods leading to successful organ decellularization. In this experiment we examine the feasibility of a decellularized liver construct to support growth of functional multilineage cells. Bio-chamb...
Par-1b is required for morphogenesis and differentiation of myoepithelial cells during salivary gland development [0.03%]
唾液腺发育过程中杯状细胞的形态建成和分化需要Par-1b
Elise M Gervais,Sharon J Sequeira,Weihao Wang et al.
Elise M Gervais et al.
The salivary epithelium initiates as a solid mass of epithelial cells that are organized into a primary bud that undergoes morphogenesis and differentiation to yield bilayered acini consisting of interior secretory acinar cells that are sur...
IL-7 suppresses osteogenic differentiation of periodontal ligament stem cells through inactivation of mitogen-activated protein kinase pathway [0.03%]
白细胞介素7通过抑制有丝分裂原活化蛋白激酶途径抑制牙周韧带干细胞成骨分化
Cong-Xiang Jian,Quan-Shui Fan,Yong-He Hu et al.
Cong-Xiang Jian et al.
Periodontal ligament stem cells (PDLSCs) are tissue-specific mesenchymal stem cells (MSCs), having an important role in regenerative therapy for teeth loss. Interleukin-7 (IL-7) is a key cytokine produced by stromal cells including MSCs, an...