Long non-coding RNA transcripts in crucian carp Brain - annotation and expression patterns in anoxia and reoxygenation [0.03%]
低氧和复氧胁迫下鲤脑组织长链非编码RNA的转录本及表达模式注释分析
Magdalena Winklhofer,Göran Erik Nilsson,Sjannie Lefevre
Magdalena Winklhofer
Long non-coding RNAs (lncRNAs) regulate diverse cellular processes, yet their role in anoxia-induced transcriptomic changes in crucian carp (Carassius carassius) - a species that endures months without oxygen at low temperatures - remains u...
5PSeq explorer: interactive analysis of Co-translational mRNA decay and ribosome dynamics [0.03%]
5PSeq浏览器：共翻译的mRNA衰变和核糖体动力学的交互式分析
Irene Stevens,Vicent Pelechano
Irene Stevens
Background: Co-translational mRNA decay occurs when 5'to 3' exonucleases follow the last translating ribosome, generating in vivo ribosome protected fragments. Degradome sequencing ;(5PSeq) therefore offers unique insight...
Human papillomavirus-encoded microRNAs: key regulators in cervical cancer development [0.03%]
人乳头瘤病毒编码的微小核糖核酸：在宫颈癌发生发展中的关键调控因子
Sanae Bencheikh,Hajar Lemriss,Amal Souiri et al.
Sanae Bencheikh et al.
Human papillomaviruses (HPVs) cause diverse cutaneous and mucosal diseases, with several genotypes strongly associated with cervical cancer. Beyond the well-established role of cellular microRNAs (miRNAs) in gene regulation, increasing evid...
Essential role of hsa-miR-203a-3p in type I interferons immune homeostasis during influenza and NDV infection [0.03%]
hsa-miR-203a-3p在流感和新城疫病毒感染中调控I型干扰素免疫稳态中的关键作用
Pramod Kumar,Ashish Kumar,Akhilesh Kumar et al.
Pramod Kumar et al.
MicroRNAs (miRNAs) are small, non-coding RNA molecules that act as essential post-transcriptional regulators in various biological processes. Many studies suggest that miRNAs may modulate the host's immune response or even viral replication...
Ruo-Mei Wang,Zi-Qiang Wang
Ruo-Mei Wang
Alzheimer's disease (AD) is a typical neurodegenerative disorder, characterized by the deposition of β-amyloid (Aβ) plaques. β- and γ-secretases generate Aβ by cleaving amyloid precursor protein. The imbalance between its production an...
LINC00852 inhibits colorectal cancer progression by regulating cell apoptosis, epithelial‒mesenchymal transition, invasion, and cuproptosis through miR-1276/LACTB [0.03%]
LINC00852通过miR-1276/LACTB调节细胞凋亡、上皮间质转化、侵袭和铜死亡抑制结直肠癌进展
Chun-Xiao Wang,Xiao-Jing Chen,Ling Zeng et al.
Chun-Xiao Wang et al.
Exploring the role of key genes in colorectal cancer (CRC) progression to identify effective targets is highly practical. Previous studies have shown that miR-1276/ACTB plays an important regulatory role in CRC. In addition to miRNA, lncRNA...
Saeed Roschdi,Takuma Kume,Riley Petersen et al.
Saeed Roschdi et al.
Poly(UG) repeats or pUG RNAs can fold into a left-handed parallel quadruplex, the pUG fold. The pUG fold directs the epigenetic amplification of RNAi in C. elegans, and pUG sequences are abundant in eukaryotic transcriptomes. Here, we repor...
Optimizing protocols for MicroRNA profiling of infant and Toddler Stool [0.03%]
优化婴儿和幼儿粪便中微小RNAs检测的方法
David A Armstrong,Shannon M Soucy,Meghan E Muse et al.
David A Armstrong et al.
Background: Despite growing interest in profiling microRNAs (miRNAs) in infant and toddler stool, no studies have compared protocols for preserving and extracting miRNAs from this specimen type. ...
Cas10 residues lining the target RNA binding channel regulate interference by distinguishing cognate target RNA from mismatched targets [0.03%]
调节干扰通过区分同源目标RNA和不匹配的目标RNA来调控Cas10中定位靶RNA结合通道的残基
Sarah Khweis,Mason Blackburn,Calvin Perdigao et al.
Sarah Khweis et al.
Type III CRISPR systems are defined by the presence of the Cas10 protein and are among the most abundant CRISPR systems in nature. Cas10 forms a complex with crRNA and several Cas proteins that surveils prokaryotic cells for foreign RNA mol...
A transformer based method for the Cap analysis of gene expression and gene expression tag associated capping region prediction in RNA [0.03%]
一种基于变压器的用于基因表达Cap分析和基因表达标签相关加帽区域预测的方法
Dibya Kanti Haldar,Avik Pramanick,Chandrama Mukherjee et al.
Dibya Kanti Haldar et al.
5' RNA capping is one of the major post-transcriptional modifications for the mobility and stability of RNA molecules. Measuring 5' caps of RNAs can help quantify expression levels of mRNAs and lncRNAs. One of the most successful RNAseq met...