USP44 promotes chemotherapeutic drug resistance of triple negative breast cancer through EZH2 protein stability [0.03%]
USP44通过EZH2蛋白稳定性促进三阴性乳腺癌的化疗耐药性
Pu Wu,Wanting Xiao,Junjie Ni et al.
Pu Wu et al.
Triple negative breast cancer (TNBC), a highly invasive breast cancer, is one of the leading causes of cancer-related mortality worldwide. Although chemotherapy remains the standard of care for TNBC, the development of chemotherapy resistan...
IFN-γ downregulates miR-4319 to enhance NLRC5 and MHC-I expression in MHC-I-deficient breast cancer cells [0.03%]
干扰素γ通过下调miR-4319促进NLRC5表达及MHCI分子的修复以增强 MHCI缺陷型乳腺癌细胞免疫原性
Ming-Zhen Zhao,Hua-Chuan Zheng,Yu Sun et al.
Ming-Zhen Zhao et al.
Sufficient MHC-I expression on cancer cells is essential for the recognition and killing of cancer cells by immune effector cytotoxic T-lymphocyte (CTL). An important mechanism of cancer immune escape is loss or down-regulation of MHC-I. Th...
Highly enriched exosomal lncRNA OIP5-AS1 regulates gastrointestinal stromal tumor (GIST) resistance to sunitinib through miR-145 and SOX9 [0.03%]
高丰度的肿瘤来源外泌体lncRNA OIP5-AS1通过miR-145/SOX9信号通路调控胃肠道间质瘤苏尼替尼耐药性
Cui-Hua Wang,Xin-Ming Yao,Chun-Xia Pan et al.
Cui-Hua Wang et al.
Targeted therapy-induced resistance is a significant factor contributing to treatment failure in patients with gastrointestinal stromal tumors (GIST). Despite the identification of the long non-coding RNA (lncRNA) OIP5-AS1 as a critical pla...
β-hydroxybutyrate, a ketone body, suppresses tumor growth, stemness, and invasive phenotypes in non-small cell lung cancer [0.03%]
β-羟丁酸通过抑制非小细胞肺癌的肿瘤生长、干性及侵袭表型来发挥抑癌作用
Yunlong Huang,Jiaxuan Ding,Yufeng Zhu et al.
Yunlong Huang et al.
Lung cancer is the most common cancer worldwide. The stemness and metastasis of tumor cells present major challenges to effective lung cancer treatment. Beta-hydroxybutyrate (BHB), a ketone body, plays a key role in various cancers. However...
Unresectable ectopic hepatocellular carcinoma in the left sub-diaphragmatic area and retroperitoneum treated with TACE: case report and literature review [0.03%]
左膈下、腹膜后不可切除的异位肝细胞癌的TACE治疗：1例报告及文献复习
Chao-Bang Xie,Zi-Jian Tang,Yang Wu et al.
Chao-Bang Xie et al.
Ectopic hepatocellular carcinoma (EHCC) demonstrates morphological and immunohistochemical features identical to conventional intrahepatic hepatocellular carcinoma (HCC), originating from ectopic liver tissue (EL), which is defined as a hep...
Correction [0.03%]
改正
Published Erratum
Cancer biology & therapy. 2025 Dec;26(1):2520651. DOI:10.1080/15384047.2025.2520651 2025
The small molecule drug CBL0137 interferes with DNA damage repair and enhances the sensitivity of NK/T-Cell lymphoma to cisplatin [0.03%]
小分子化合物CBL0137干扰DNA修复并增强鼻型NK/T细胞淋巴瘤对顺铂的敏感性
Hang Gu,Siyu Qian,Yue Zhang et al.
Hang Gu et al.
This study aimed to investigate the in vitro and in vivo antitumor effects and mechanisms of the small molecule anticancer drug CBL0137 in NK/T-cell lymphoma (NKTCL), as well as its efficacy when combined with chemotherapy or immunotherapy....
Lung cancer cell derived sEVs enhance the metastasis of non-small cell lung cancer via SNHG12/miR-326/SLC7A11 axis [0.03%]
肺癌细胞来源的sEVs通过SNHG12/miR-326/SLC7A11轴促进非小细胞肺癌转移
Yiqian Liu,Ling Zhang,Jian Wang et al.
Yiqian Liu et al.
Abnormally expressed long non-coding (lnc)RNAs are closely associated with the pathogenesis of non-small cell lung cancer (NSCLC); thus, the present study aimed to investigate the potential role of SNHG12 in NSCLC. Transmission electron mic...
Suppression of pseudogene MT2P1 transcription induced by E2F7 inhibits hepatocellular carcinoma cell proliferation and facilitates apoptosis via preserving its parental gene [0.03%]
E2F7通过抑制假基因MT2P1转录抑制肝癌细胞增殖并促进其凋亡以维持其亲代基因功能
Yiquan Lu,Yifan Zhang,Fengjie Hao et al.
Yiquan Lu et al.
The majority of the pseudogenes are inert in normal transcription. Their transcripts are mostly attributed to non-coding RNAs that play various functions in human tumorigenicity and progression. Distinctively, pseudogene MT2P1 is universall...
Efficacy of brachytherapy for locally advanced bladder cancer: a single-center retrospective clinical study [0.03%]
近距离放射治疗局部晚期膀胱癌的疗效分析：单中心回顾性研究
Xuebing Han,Huiqing Chen,Bin Wang
Xuebing Han
To explore the feasibility, safety, and effectiveness of brachytherapy of locally advanced bladder cancer, clinical data of 86 patients with locally advanced bladder cancer treated in the Department of Urology Surgery, Shanxi Provincial Can...