Early GLP-1 Agonist Use and Cancer Risk in Type 2 Diabetes: A Real-World Data Cohort Study [0.03%]
GLP-1受体激动剂早期使用与2型糖尿病患者癌症风险的关系：真实世界队列研究
Cheng-Hsun Chuang,Ping-Kun Tsai,Shih-Wen Kao et al.
Cheng-Hsun Chuang et al.
Background: To determine whether initiating a glucagon-like peptide-1 receptor agonist (GLP-1 RA) within 3 months of type 2 diabetes (T2DM) diagnosis alters the subsequent risk of overall and site-specific cancer and whet...
Biological Features of KLC2 Mutations in Chronic Myeloid Leukemia and Their Contribution to Inducing Drug Resistance [0.03%]
慢性粒细胞白血病中KLC2突变的生物学特征及其诱导药物耐药性的贡献
Rabindranath Bera,Yotaro Ochi,Ying-Jung Huang et al.
Rabindranath Bera et al.
Background: Breakpoint Cluster Region-Abelson (BCR::ABL1) fusion protein is essential in the pathogenesis of chronic myeloid leukemia (CML); however, the chronic-to-blast phase transformation remains elusive. We identifie...
Effectiveness and Safety of Lenvatinib and Everolimus after Immune Checkpoint Inhibitors in Metastatic Renal Cell Cancer: A Systematic Review [0.03%]
免疫检查点抑制剂治疗后仑伐替尼联合依维莫司治疗转移性肾细胞癌的疗效和安全性：一项系统综述
Giacomo Iovane,Luca Traman,Michele Maffezzoli et al.
Giacomo Iovane et al.
Background: While the treatment of metastatic renal cell carcinoma (mRCC) is evolving due to immune checkpoint inhibitors (ICIs), optimal strategies for later lines of therapy have yet to be defined. The combination of le...
AGPAT3 Regulates Immune Microenvironment in Osteosarcoma via Lysophosphatidic Acid Metabolism [0.03%]
AGPAT3通过溶血磷脂酸代谢调节骨肉瘤免疫微环境
Shenghui Su,Yu Zeng,Jiaxin Chen et al.
Shenghui Su et al.
Background: Recent studies have shown glycerolipid metabolism played an essential role in multiple tumors, however, its function in osteosarcoma is unclear. This study aimed to explore the role of glycerolipid metabolism ...
Retraction: MicroRNA-133b Inhibits Proliferation, Cellular Migration, and Invasion via Targeting LASP1 in Hepatocarcinoma Cells [0.03%]
撤稿：MicroRNA-133b通过靶向LASP1抑制肝癌细胞增殖、迁移和侵袭
Oncology Research Editorial Office
Oncology Research Editorial Office
[This retracts the article DOI: 10.3727/096504017X14850151453092.]. © 2026 The Author.
HE4 Might Participate in Extracellular Matrix Remodeling in Ovarian Cancer via Activation of Fibroblasts [0.03%]
HE4可能通过激活成纤维细胞参与卵巢癌的细胞外基质重塑
Yimin Liu,Bin Liu,Huabin Gao et al.
Yimin Liu et al.
Objectives: High-grade serous ovarian cancer (HGSOC), the most common subtype of epithelial ovarian cancer (EOC), exhibits a mesenchymal phenotype characterized by fibrotic stroma and poor prognosis. Human epididymis prot...
STC2+ Malignant Cell State Associated with EMT, Tumor Microenvironment Remodeling, and Poor Prognosis Revealed by Single-Cell and Spatial Transcriptomics in Colorectal Cancer [0.03%]
结直肠癌单细胞和空间转录组揭示与EMT、肿瘤微环境重塑和预后不良相关STC2恶性细胞状态
Kai Gui,Tianyi Yang,Chengying Xiong et al.
Kai Gui et al.
Objectives: The mechanism by which specific tumor subsets in colorectal cancer (CRC) use alternative metabolic pathways, particularly those modulated by hypoxia and fructose, to alter the tumor microenvironment (TME) rema...
ZMIZ2/MCM3 Axis Participates in Triple-Negative Breast Cancer Progression [0.03%]
ZMIZ2/MCM3轴参与三阴性乳腺癌的发展进程
Xiaopan Zou,Meiyang Sun,Xin Jiang et al.
Xiaopan Zou et al.
Objective: Triple-negative breast cancer (TNBC) is highly aggressive and lacks an effective targeted therapy. This study aimed to elucidate the functions and possible mechanisms of action of zinc finger miz-type containin...
PNP as a Metabolic and Prognostic Driver of Breast Cancer Aggressiveness: Insights from Patient Tissue and Cell Models [0.03%]
乳腺癌进展中的代谢及预后驱动因素PNP：来自病人组织和细胞模型的见解
Sarra B Shakartalla,Iman M Talaat,Nival Ali et al.
Sarra B Shakartalla et al.
Objectives: Breast cancer (BC) is the leading cause of cancer-related mortality in women, largely due to metastasis. This study aims to explore the role of purine nucleoside phosphorylase (PNP), a key enzyme in purine met...
RP11-Derived Long Non-Coding RNAs in Hepatocellular Carcinoma: Hidden Treasures in Plain Sight [0.03%]
乙型肝炎和丙型肝炎所致的肝细胞癌中RP11衍生的长链非编码RNA：显而易见的隐藏宝藏
Se Ha Jang,Hyung Seok Kim,Jung Woo Eun
Se Ha Jang
Hepatocellular carcinoma (HCC) remains one of the most prevalent and lethal malignancies worldwide. Long non-coding RNAs (lncRNAs) have emerged as crucial regulators of gene expression and cancer progression, yet the functional diversity of...