A Holistic Review of Oncological Drug Targets and Trajectories of Resistance in Cancer Therapy [0.03%]
肿瘤药物靶点及癌症治疗耐药性演变的全面回顾
Harpreet Kaur,Dhrubalochan Rana,Sowvik Bag et al.
Harpreet Kaur et al.
The prolonged and intricate history of oncological treatments has transitioned significantly since the introduction of chemotherapy. Substantial therapeutic benefits in cancer therapy have been achieved by the integration of conventional tr...
BHLHE40 Is a Transcriptional Regulatory Target of NFE2L3 in Triple-Negative Breast Cancer [0.03%]
NFE2L3的靶基因BHLHE40在三阴性乳腺癌中的转录调节作用
Shail Rakesh Modi,Terrick Andey,George Acquaah-Mensah
Shail Rakesh Modi
Objectives: The current treatment options and therapeutic targets for triple-negative breast cancer (TNBC), an aggressive subtype of breast cancer (BrCA), are limited. This study aimed to identify novel biomarkers and tra...
Targeting Sphingolipids in Breast Cancer: From Tumor Biology to Therapeutic Strategies [0.03%]
乳腺癌中的鞘脂靶向治疗：从肿瘤生物学至治疗策略
Min Hee Kim,Boyoon Huh,Joo-Won Park et al.
Min Hee Kim et al.
Breast cancer is one of the most prevalent malignancies among women and comprises a heterogeneous spectrum of molecular subtypes with distinct biological behaviors. Among various regulatory molecules, sphingolipids play pivotal roles in dyn...
Targeting HER2-Positive HCC1954 Breast Cancer Cells by Novel Thiazole-Dihydrobenzisoxazoles: In-Depth Design, Synthesis and Initial In Vitro Study [0.03%]
新型噻唑-二氢苯并异噁唑化合物对HER2阳性HCC1954乳腺癌细胞的靶向作用：详细设计、合成及初步体外研究
Yuri A Piven,Danila V Sorokin,Nastassia A Varabyeva et al.
Yuri A Piven et al.
Background: The most aggressive forms of breast cancer are characterized by independence from steroid hormones but a strong dependence on growth factors. In such cancer cells, oncogenic receptors, including human epiderma...
Male Breast Cancer: Epidemiology, Diagnosis, Molecular Mechanisms, Therapeutics, and Future Prospective [0.03%]
男性乳腺癌：流行病学、诊断、分子机制、治疗和未来趋势
Ashok Kumar Sah,Ranjay Kumar Choudhary,Velilyaeva Alie Sabrievna et al.
Ashok Kumar Sah et al.
Male breast cancer (MBC) is rare, representing 0.5%-1% of all breast cancers, but its incidence is increasing due to improved diagnostics and awareness. MBC typically presents in older men, is human epidermal growth factor receptor 2 (HER2)...
Retraction: Truncated Bid Overexpression Induced by Recombinant Adenovirus Cre/LoxP System Suppresses the Tumorigenic Potential of CD133 + Ovarian Cancer Stem Cells [0.03%]
卵巢癌干细胞中截短型Bid过表达抑制肿瘤潜能的撤回：重组腺病毒Cre/Loxp系统诱导截短型Bid过表达抑制CD133+ ovarian cancer干细胞的致瘤性
Oncology Research Editorial Office
Oncology Research Editorial Office
[This retracts the article DOI: 10.3727/096504016X14765492198706.]. © 2026 The Author.
CBX4 Drives Gastric Cancer Progression by Activating β-Catenin Signaling [0.03%]
CBX4通过激活β-连环蛋白信号促进胃癌进展
Wendong Jia,Ting Zhang,Ziying Zhang et al.
Wendong Jia et al.
Objectives: Chromobox 4 (CBX4), a polycomb protein family member linked to tumor pathogenesis via dysregulation, has an incompletely defined role in gastric cancer (GC). The study aimed to investigate the role and mechani...
The Role of Exosomes as a Key Factor of Cytostatic Resistance in Cancer: Mechanisms of Action, Potential Biomarkers, and Possible Exosome-Based Therapies [0.03%]
外泌体在癌症细胞静止耐药性中的关键作用：作用机制、潜在生物标志物及可能的基于外泌体的治疗方法
Sandra Kałużna,Monika Świerczewska,Sylwia Ciesiółka et al.
Sandra Kałużna et al.
The last research focuses on the role of exosomes in cancer treatment. Exosomes are extracellular vesicles. They can be secreted by cancer cells, and they can modulate chemotherapy sensitivity. Determining exosomal content opens the possibi...
CSRNP1 Promotes Apoptosis and Mitochondrial Dysfunction via ROS-Mediated JNK/p38 MAPK Pathway Activation in Hepatocellular Carcinoma [0.03%]
癌胚蛋白CSRNP1通过ROS介导的JNK/p38MAPK通路激活促进肝细胞癌凋亡和线粒体功能障碍
Huihui Shi,Lei Chen,Juan Huang et al.
Huihui Shi et al.
Background: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. This study aimed to identify key genes involved in HCC development and elucidate their molecular mechanisms, w...
Circulating Tumor DNA in Cervical Cancer: Clinical Utility and Medico-Legal Perspectives [0.03%]
宫颈癌的循环肿瘤DNA：临床应用与法律观点
Abdulrahman K Sinno,Aisha Mustapha,Navya Nair et al.
Abdulrahman K Sinno et al.
Cervical cancer related to human papillomavirus (HPV) is a leading cause of cancer-related mortality among women worldwide. Cancer cells release fragments of their DNA, known as circulating tumor DNA (ctDNA), which can be detected in bodily...