CSRNP1 Promotes Apoptosis and Mitochondrial Dysfunction via ROS-Mediated JNK/p38 MAPK Pathway Activation in Hepatocellular Carcinoma [0.03%]
癌胚蛋白CSRNP1通过ROS介导的JNK/p38MAPK通路激活促进肝细胞癌凋亡和线粒体功能障碍
Huihui Shi,Lei Chen,Juan Huang et al.
Huihui Shi et al.
Background: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. This study aimed to identify key genes involved in HCC development and elucidate their molecular mechanisms, w...
Circulating Tumor DNA in Cervical Cancer: Clinical Utility and Medico-Legal Perspectives [0.03%]
宫颈癌的循环肿瘤DNA：临床应用与法律观点
Abdulrahman K Sinno,Aisha Mustapha,Navya Nair et al.
Abdulrahman K Sinno et al.
Cervical cancer related to human papillomavirus (HPV) is a leading cause of cancer-related mortality among women worldwide. Cancer cells release fragments of their DNA, known as circulating tumor DNA (ctDNA), which can be detected in bodily...
P2RX1 Influences the Prognosis of Ph+/Ph-Like ALL through Energy and Calcium Metabolism [0.03%]
嘌呤受体P2RX1通过能量及钙代谢影响Ph+和Ph-like急淋的预后
Xiangmei Ye,Baoyi Yang,Xin Zhang et al.
Xiangmei Ye et al.
Objectives: Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia and Philadelphia-like B-cell acute lymphoblastic leukemia (Ph+/Ph-like ALL) constitute the majority of relapsed/refractory B-ALL (R/R B-ALL)...
Real-World Outcomes of First-Line Palbociclib Plus Endocrine Therapy for HR+/HER2- Metastatic Breast Cancer in Japan: A Single-Center Retrospective Study [0.03%]
帕博西利联合内分泌治疗HR阳性/HER2阴性转移性乳腺癌的真实世界预后：一项单中心回顾性研究
Keiko Yanagihara,Masato Yoshida,Kensaku Awaji et al.
Keiko Yanagihara et al.
Background: Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors have transformed the management of hormone receptor-positive/HER2-negative (HR+/HER2-) advanced breast cancer, yet evidence for elderly or poor-performance patie...
ELK4 Promotes Vasculogenic Mimicry in Oral Squamous Cell Carcinoma via Driving DHFR Transcriptional Activation [0.03%]
ELK4通过驱动DHFR转录激活促进口腔鳞状细胞癌的血管生成模拟现象
Yongle Qiu,Kunshan Li,Wenjing Wang et al.
Yongle Qiu et al.
Background: The regulatory mechanisms governing vasculogenic mimicry (VM) in oral squamous cell carcinoma (OSCC) remain largely undefined. This study aimed to identify critical factors and elucidate the epigenetic mechani...
Application Value and Research Frontiers of Immunotherapy in Glioblastoma: A Bibliometric and Visualized Analysis [0.03%]
免疫治疗胶质母细胞瘤的应用价值及研究前沿：基于文献计量和可视化分析
Kun Deng,Jianliang Huang,Danyang Li et al.
Kun Deng et al.
Background: Glioblastoma (GBM) prognosis has seen little improvement over the past two decades. While immunotherapy has revolutionized cancer treatment, its impact on GBM remains limited. To characterize the evolving rese...
Retraction: MicroRNA-148a Acts as a Tumor Suppressor in Osteosarcoma via Targeting Rho-Associated Coiled-Coil Kinase [0.03%]
撤稿：MicroRNA-148a通过靶向Rho相关卷曲螺旋激酶在骨肉瘤中发挥肿瘤抑制作用
Oncology Research Editorial Office
Oncology Research Editorial Office
[This retracts the article DOI: 10.3727/096504017X14850134190255.]. © 2026 The Author.
Integrative Multi-Omics Analysis and Experiments Validation Identify COX5B as a Novel Therapeutic Target for Lung Adenocarcinoma [0.03%]
整合多组学分析和实验验证识别出COX5B作为肺腺癌的新型治疗靶点
Lv Ling,Minying Lu,Ling Ye et al.
Lv Ling et al.
Background: A significant proportion of patients still cannot benefit from existing targeted therapies and immunotherapies, making the search for new treatment strategies extremely urgent. In this study, we combined integ...
Ferroptosis: Mechanisms, Comparison with Cuproptosis and Emerging Horizons in Therapeutics [0.03%]
铁死亡：机制、与铜依赖性细胞坏死的比较及治疗新策略展望
Shujie Yin,Zong Li,Wen-Bin Ou
Shujie Yin
Ferroptosis is an iron-dependent, excessive lipid peroxidation-driven form of regulated cell death. The core mechanisms of ferroptosis include lipid peroxidation cascade, System Xc --glutathioneglutathione peroxidase 4 axis, iron and lipid ...
miR-512-3p/RPS6KA2 Axis Regulates Cisplatin Resistance in Ovarian Cancer via Autophagy and Ferroptosis [0.03%]
microRNA-512-3p/RPS6KA2轴通过自噬和铁死亡调节卵巢癌顺铂耐药性
Jianfa Wu,Huang Chen,Sihong Wang et al.
Jianfa Wu et al.
Objectives: Ribosomal protein S6 kinase A2 (RPS6KA2) has been identified as a potential prognostic biomarker in several cancers, including breast cancer, glioblastoma, and prostate cancer. However, its functional signific...