Circular RNAs: Key Regulators of Tumor Metabolic Reprogramming and Clinical Translation [0.03%]
环状RNA：肿瘤代谢重编程的关键调节因子及临床转化
Yimao Wu,Yitong Liu,Ruowei Sun et al.
Yimao Wu et al.
Tumor metabolic reprogramming is a core hallmark of cancer, characterized by pathways such as aerobic glycolysis, aberrant lipid metabolism, and glutaminolysis that support rapid proliferation and immunosuppressive microenvironments. Circul...
Advances in Targeted and Immunotherapy for High-Risk Cutaneous Malignancies [0.03%]
高危皮肤恶性肿瘤的靶向和免疫治疗进展
Amy J Petty,Drew A Emge,Adela R Cardones
Amy J Petty
Skin cancer remains the most commonly diagnosed malignancy worldwide, with basal cell carcinoma (BCC), cutaneous squamous cell carcinoma (cSCC), and melanoma representing the most clinically significant types. While traditional treatments a...
miR-449a: A Novel Biomarker for Diagnosis, Prognosis, and Treatment Response in Locally Advanced Laryngeal Squamous Cell Carcinoma [0.03%]
miR-449a：局部晚期喉部鳞状细胞癌诊断、预后和治疗反应的新型生物标志物
Amal F Gharib,Ohud Alsalmi,Hayaa M Alhuthali et al.
Amal F Gharib et al.
Background: Locally advanced laryngeal squamous cell carcinoma (LA-LSCC) presents clinical challenges due to the lack of reliable non-invasive biomarkers. This study aimed to evaluate miR-449a as a diagnostic and prognost...
Retraction: MicroRNA-138 Inhibits Cell Growth, Invasion, and EMT of Non-Small Cell Lung Cancer via SOX4/p53 Feedback Loop [0.03%]
撤稿：MicroRNA-138通过SOX4/p53反馈回路抑制非小细胞肺癌的细胞生长、侵袭和上皮间质转化
Oncology Research Editorial Office
Oncology Research Editorial Office
[This retracts the article DOI: 10.3727/096504017X14973124850905.]. © 2026 The Author. Published by Tech Science Press.
S100A14 Facilitates Pancreatic Cancer Progression via S100A16-Mediated p53 Suppression [0.03%]
S100A14通过S100A16介导的p53抑制促进胰腺癌进展
Pingping Hu,Zhenhao Fei,Jianhua Bai et al.
Pingping Hu et al.
Objectives: Pancreatic cancer (PC) is characterized by poor prognosis due to its limited treatment choices and delayed detection. S100A14 has been implicated in tumor progression, yet its regulatory hierarchy and function...
Investigating the Immune Effects of Radiotherapy in Non-Small Cell Lung Cancer-Results of the PD-RAD Study [0.03%]
放疗对非小细胞肺癌免疫效应的影响-PD-RAD研究结果分析
Shuhui Cheng,Tiana Kordbacheh,Antonia Banyard et al.
Shuhui Cheng et al.
Objectives: The PACIFIC trial established the benefit of durvalumab following chemo-radiotherapy for stage III non-small cell lung cancer (NSCLC). However, the concurrent use of radiotherapy (RT) and durvalumab (PACIFIC-2...
Interplay of Interleukin-1 β and Curcumin on VEGF Expression in Breast Cancer Cells [0.03%]
细胞因子IL-1 β和姜黄素对乳腺癌细胞VEGF表达的互作关系研究
Norbert Nass,Atanas Ignatov,Thomas Kalinski
Norbert Nass
Objectives: Vascular endothelial growth factor (VEGF) regulates tumor vascularization in response to hypoxia and inflammatory signals. The polyphenol curcumin is supposed to interfere with inflammation-induced VEGF secret...
Clinical Integration of Menin Inhibitors in AML: Evolving Data and Therapeutic Perspectives [0.03%]
MENIN抑制剂在急性髓系白血病临床整合中的演变数据和治疗观点
Tiffany Chen,Grace Kim,Yekta Rahimi et al.
Tiffany Chen et al.
Acute myeloid leukemia (AML) remains a biologically heterogeneous disease with historically limited targeted therapies and poor outcomes. The development of menin inhibitors represents a promising shift, particularly for patients harboring ...
Clinical and Functional Characterization of PDE1A as a Wnt/ β-Catenin-Linked Biomarker of Progression and Platinum Resistance in Epithelial Ovarian Cancer [0.03%]
PDE1A的临床和功能表征及其作为上皮性卵巢癌进展和铂耐药相关Wnt/-catenin连接生物标志物的研究
Gwan Hee Han,Hee Yun,Joon-Yong Chung et al.
Gwan Hee Han et al.
Objectives: Phosphodiesterase 1A (PDE1A) regulates intracellular cyclic nucleotide signaling and has been implicated in tumor progression, but its clinical relevance and functional role in epithelial ovarian cancer (EOC),...
Novel Small Molecule DZ-865B Effectively Degrades BCL6, Promotes Apoptosis and Reduces Proliferation of Diffuse Large B-Cell Lymphoma Cells [0.03%]
新型小分子DZ-865B可有效降解DLBCL细胞中的BCL6蛋白并促进其凋亡和增殖抑制作用
Yanfeng Wang,Xinyi Chen,Yichen Yin et al.
Yanfeng Wang et al.
Objectives: B-cell lymphoma 6 (BCL6) is a transcriptional repressor whose overexpression is closely linked to the progression of diffuse large B-cell lymphoma (DLBCL), making it a promising therapeutic target. This study ...