MicroRNA 495 Inhibits Proliferation and Metastasis and Promotes Apoptosis by Targeting Twist1 in Gastric Cancer Cells [0.03%]
微RNA495通过靶向胃癌细胞中Twist1来抑制增殖和转移并促进凋亡
Chao Liu,Min Jian,Hong Qi et al.
Chao Liu et al.
Recently, microRNAs (miRNAs) have been reported to participate in multiple biological processes. However, the effects of miR-495 on gastric cancer (GC) remain unclear. The purpose of this study was to explore the functions of miR-495 in GC ...
miR-223-5p Suppresses Tumor Growth and Metastasis in Non-Small Cell Lung Cancer by Targeting E2F8 [0.03%]
微RNA-223通过靶向E2F8抑制非小细胞肺癌的生长和转移
Liyan Dou,Kaiyu Han,Mochao Xiao et al.
Liyan Dou et al.
miR-223-5p has been demonstrated to regulate the development and progression of various cancers, such as hepatocellular carcinoma, breast cancer, and gastric carcinoma. However, the role of miR-223-5p in non-small cell lung cancer (NSCLC) r...
Curcumin suppress the growth of hepatocellular carcinoma via down-regulating SREBF1 [0.03%]
姜黄素通过下调SREBF1抑制肝癌细胞增殖
Zhen You,Bei Li,Jingchang Xu et al.
Zhen You et al.
The aim of this study is to investigate the pharmacological effect of curcumin on hepatocellular carcinoma (HCC) Huh7 and PLC cells and to explore its mechanism in the pathological process by screening possible target genes. MTT assay was u...
Kinesin Motor Protein KIFC1 Is a Target Protein of miR-338-3p and Is Associated With Poor Prognosis and Progression of Renal Cell Carcinoma [0.03%]
微RNA-338-3p靶蛋白动力蛋白激酶间质细胞骨架相关蛋白1与肾细胞癌预后及进展的关系研究
Gang Li,Tie Chong,Jie Yang et al.
Gang Li et al.
KIFC1 (kinesin family member C1) plays a critical role in clustering of extra centrosomes in various cancer cells and thus could be considered as a promising therapeutic target. However, whether KIFC1 is involved in the procession of renal ...
miR-632 Promotes Laryngeal Carcinoma Cell Proliferation, Migration, and Invasion Through Negative Regulation of GSK3β [0.03%]
miR-632通过抑制GSK3β促进喉癌细胞增殖、迁移和侵袭
Zhong-Xin Zhou,Zu-Ping Zhang,Ze-Zhang Tao et al.
Zhong-Xin Zhou et al.
Laryngeal cancer, one of the most common head and neck malignancies, is an aggressive neoplasm. Increasing evidence has demonstrated that microRNAs (miRNAs) exert important roles in oncogenesis and progression of diverse types of human canc...
MicroRNA 615-3p Inhibits the Tumor Growth and Metastasis of NSCLC via Inhibiting IGF2 [0.03%]
microRNA 615-3p通过抑制IGF2抑制非小细胞肺癌的肿瘤生长和转移
Jiangtao Liu,Yanli Jia,Lijuan Jia et al.
Jiangtao Liu et al.
MicroRNAs are essential regulators of cancer-associated genes at the posttranscriptional level, and their expression is altered in cancer tissues. Herein we sought to identify the regulation of miR-615-3p in NSCLC progression and its mechan...
MicroRNA-1277 Inhibits Proliferation and Migration of Hepatocellular Carcinoma HepG2 Cells by Targeting and Suppressing BMP4 Expression and Reflects the Significant Indicative Role in Hepatocellular Carcinoma Pathology and Diagnosis After Magnetic Resonance Imaging Assessment [0.03%]
MicroRNA-1277通过靶向抑制BMP4表达抑制肝癌HepG2细胞增殖和迁移并在磁共振成像评估后的肝癌病理及诊断中发挥重要作用
Xinshan Cao,Ling Xu,Quanyuan Liu et al.
Xinshan Cao et al.
Our study aimed to investigate the roles and possible regulatory mechanism of miR-1277 in the development of hepatocellular carcinoma (HCC). HCC patients were identified from patients who were diagnosed with focal liver lesions using magnet...
miR-449a Suppresses Tumor Growth, Migration, and Invasion in Non-Small Cell Lung Cancer by Targeting a HMGB1-Mediated NF-κB Signaling Pathway [0.03%]
microRNA-449a通过靶向HMGB1介导的NF-κB信号通路抑制非小细胞肺癌生长、迁移和侵袭
Dandan Wu,Jun Liu,Jianliang Chen et al.
Dandan Wu et al.
MicroRNAs (miRNAs) have been reported to be involved in many human cancers and tumor progression. The dysregulation of miR-449a is found in many types of malignancies and is associated with tumor growth, migration, and invasion. However, it...
TRIM14 Promotes Breast Cancer Cell Proliferation by Inhibiting Apoptosis [0.03%]
TRIM14通过抑制细胞凋亡促进乳腺癌细胞增殖
Gaowu Hu,Wei Pen,Ming Wang
Gaowu Hu
Tripartite motif-containing 14 (TRIM14) is abnormally expressed in several human cancers. However, the function and expression of TRIM14 in human breast cancer are still largely unknown. To understand the biological function of TRIM14 in br...
MicroRNA-338-3p Inhibits Proliferation and Promotes Apoptosis of Multiple Myeloma Cells Through Targeting Cyclin-Dependent Kinase 4 [0.03%]
microRNA-338-3p通过靶向细胞周期素依赖性激酶4抑制多发性骨髓瘤细胞增殖并促进其凋亡
Yang Cao,Xu Shi,Yingmin Liu et al.
Yang Cao et al.
MicroRNA-338-3p (miR-338-3p) has been reported to be a tumor suppressor in multiple cancer types. However, the biological role of miR-338-3p and its underlying mechanism in multiple myeloma (MM) remain unclear. In the present study, we inve...