The Interaction Between lncRNA SNHG1 and miR-140 in Regulating Growth and Tumorigenesis via the TLR4/NF-κB Pathway in Cholangiocarcinoma [0.03%]
长链非编码RNA SNHG1通过TLR4 / NF-κB通路在调节胆管癌生长和致瘤性方面与miR-140的相互作用
Zhen Li,Xin Li,Xiao Du et al.
Zhen Li et al.
Cholangiocarcinoma (CCA) is the second most common primary hepatobiliary carcinoma. The long noncoding RNA (lncRNA) small nucleolar RNA host gene 1 (SNHG1) has been reported to contribute to the progression of multiple cancers. Nonetheless,...
NOTCH3 Overexpression and Posttranscriptional Regulation by miR-150 Were Associated With EGFR-TKI Resistance in Lung Adenocarcinoma [0.03%]
表皮生长因子受体酪氨酸激酶抑制剂耐药的肺腺癌中NOTCH3过表达及其通过miR-150的翻译后调控机制
Youwei Zhang,Bi Chen,Yongsheng Wang et al.
Youwei Zhang et al.
Acquired resistance remains a key challenge in epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) therapy in lung adenocarcinoma (LUAD). Recent studies have shown that Notch signaling is associated with drug resistanc...
Jianlin Wang,Wenjie Song,Weiwei Shen et al.
Jianlin Wang et al.
MicroRNA-200a (miR-200a) is frequently downregulated in most cancer types and plays an important role in carcinogenesis and cancer progression. In this study, we determined that miR-200a was downregulated in hepatocellular carcinoma (HCC) t...
Published Erratum
Oncology research. 2019 Feb 5;27(2):281-282. DOI:10.3727/096504019X15476499940873 2019
1,25(OH)2D3 Attenuates IL-1β-Induced Epithelial-to-Mesenchymal Transition Through Inhibiting the Expression of lncTCF7 [0.03%]
1,25(OH)₂D₃通过抑制lncTCF7的表达减轻IL-1β诱导的上皮间质转化效应
Tengyu Li,Jing Zhu,Shuai Zuo et al.
Tengyu Li et al.
The activated form of vitamin D3, 1,25-dihydroxyvitamin D3 [1,25(OH)2D3], regulates numerous cellular processes, including inhibition of cancer progression. IL-1β has been reported to facilitate cancer development, especially by inducing a...
Exosomal miR-1228 From Cancer-Associated Fibroblasts Promotes Cell Migration and Invasion of Osteosarcoma by Directly Targeting SCAI [0.03%]
肿瘤相关成纤维细胞源外泌体miR-1228通过直接靶向SCAI促进骨肉瘤细胞迁移和侵袭
Jian-Wei Wang,Xiao-Feng Wu,Xiao-Juan Gu et al.
Jian-Wei Wang et al.
Cancer-associated fibroblasts (CAFs) play a predominant role in regulating tumor progression. Understanding how CAFs communicate with osteosarcoma is crucial for developing novel approaches for osteosarcoma therapy. Exosomes are able to tra...
Clinical Characteristics and Molecular Patterns of RET-Rearranged Lung Cancer in Chinese Patients [0.03%]
中国RET基因重排肺癌患者的临床特征和分子谱分析
Kai Zhang,Huajun Chen,Ye Wang et al.
Kai Zhang et al.
RET rearrangement has been proven as an oncogenic driver in patients with lung cancer. However, the prevalence, clinical characteristics, molecular features, and therapeutic options in RET-rearranged patients remain unclear, especially in C...
Astragaloside IV Inhibits the Progression of Non-Small Cell Lung Cancer Through the Akt/GSK-3β/β-Catenin Pathway [0.03%]
astragaloside IV通过Akt/GSK-3β/β-catenin途径抑制非小细胞肺癌的发展
Liwei Jia,Dongying Lv,Shuang Zhang et al.
Liwei Jia et al.
Astragaloside IV (AS-IV) is an active ingredient in Astragalus membranaceus and is involved in various biological processes, such as regulating the immune system, and counteracting inflammation and malignancy. The aim of this study was to e...
MicroRNA-152 Acts as a Tumor Suppressor MicroRNA by Inhibiting Krüppel-Like Factor 5 in Human Cervical Cancer [0.03%]
microRNA-152通过抑制Krüppel样因子5在人类宫颈癌中发挥抑癌作用
Haiyan Zhang,Yanxia Lu,Surong Wang et al.
Haiyan Zhang et al.
Aberrant expression of microRNA-152 (miR-152) is frequently observed in human cancers including ovarian cancer, breast cancer, prostate cancer, and gastric cancer. However, its expression and functional role in cervical cancer (CC) are poor...
Anemia Is a Novel Predictive Factor for the Onset of Severe Chemotherapy-Induced Peripheral Neuropathy in Lymphoma Patients Receiving Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone Therapy [0.03%]
贫血是淋巴瘤患者在接受利妥昔单抗联合环磷酰胺、多柔比星、长春新碱和泼尼松治疗时发生严重化疗诱导的外周神经病变的新预测因素
Takashi Saito,Atsuo Okamura,Junichiro Inoue et al.
Takashi Saito et al.
Chemotherapy-induced peripheral neuropathy (CIPN) frequently occurs in lymphoma patients receiving R-CHOP, a drug combination therapy. Although severe CIPN may lead to reduction and/or discontinuation of the medication, predictive factors o...
Efficacy Evaluation of Imatinib for the Treatment of Melanoma: Evidence From a Retrospective Study [0.03%]
伊马替尼治疗恶性黑色素瘤疗效的回顾性研究证据分析
Xiaoting Wei,Lili Mao,Zhihong Chi et al.
Xiaoting Wei et al.
Melanoma is an aggressive malignancy with a poor prognosis. Current studies show that imatinib treatment is a promising approach in treating advanced melanoma patients harboring c-Kit mutations or amplifications. We retrospectively analyzed...