Pan-Cancer Analysis of Enhancer-Induced PAN3-AS1 and Experimental Validation as a WFDC13-Promoting Factor in Colon Cancer [0.03%]
泛癌分析诱导PAN3-AS1的增强子及其作为结直肠癌中WFDC13促进因子的实验验证
Xu Guo,Yanan Yu,Xiaolin Ma et al.
Xu Guo et al.
Background: Long non-coding RNAs (lncRNAs) act as epigenetic regulators for tumor hallmarks. This investigation sought to probe the carcinogenic trait of PAN3-AS1 across pan-cancer comprehensively. ...
The Efficacy and Safety of B-Cell Maturation Antigen (BCMA) Antibody-Drug Conjugates (ADC) in Development against Cancer: A Systematic Review [0.03%]
在开发中用于抗癌的B细胞成熟抗原(BCMA)抗体药物偶联物(ADC)的有效性和安全性:一项系统性综述
Jing Shan,Catherine King,Harunor Rashid et al.
Jing Shan et al.
Objectives: B-cell maturation antigen (BCMA)-targeted antibody-drug conjugates (ADCs) have emerged as promising therapies for relapsed/refractory multiple myeloma (RRMM), but the overall efficacy and safety profile is unc...
Branched-Chain Amino Acid Metabolic Reprogramming and Cancer: Molecular Mechanisms, Immune Regulation, and Precision Targeting [0.03%]
支链氨基酸代谢重编程与癌症:分子机制、免疫调控及精准治疗靶点
Dongchi Cai,Jialin Ji,Chunhui Yang et al.
Dongchi Cai et al.
Metabolic reprogramming involving branched-chain amino acids (BCAAs)-leucine, isoleucine, and valine-is increasingly recognized as pivotal in cancer progression, metastasis, and immune modulation. This review comprehensively explores how ca...
Development of Patient-Derived Conditionally Reprogrammed 3D Breast Cancer Culture Models for Drug Sensitivity Evaluation [0.03%]
基于患者衍生的条件性重编程三维乳腺癌培养模型的药物敏感性评价模型构建及应用研究
Jing Cai,Haoyun Zhu,Weiling Guo et al.
Jing Cai et al.
Background: Therapeutic responses of breast cancer vary among patients and lead to drug resistance and recurrence due to the heterogeneity. Current preclinical models, however, are inadequate for predicting individual pat...
PFDN6L Gene Predicts Good Prognosis Associated with Its Inhibition of the Stem-Ness Properties in Hepatocellular Carcinoma [0.03%]
PFDN6L基因通过抑制肝癌干性特性预测良好的预后
Fangyuan Li,Xiaoyuan Hu,Xiaoge Gao et al.
Fangyuan Li et al.
Background: Liver cancer stem cells (LCSCs) are recognized as pivotal drivers of hepatocellular carcinoma (HCC) progression; however, the molecular mechanisms maintaining their stem-like phenotype remain largely unresolve...
Outcomes and Toxicity of Adult Medulloblastoma Treated with Pediatric Multimodal Protocols: A Single-Institution Experience [0.03%]
成人髓母细胞瘤采用儿童多模式方案治疗的结局和毒性:单中心经验
Antonio Ruggiero,Dario Talloa,Alberto Romano et al.
Antonio Ruggiero et al.
Background: Adult medulloblastoma (MB) represents less than 1% of central nervous system malignancies, lacking standardized therapeutic approaches due to its rarity. This retrospective single-center analysis aimed to asse...
Transglutaminase 7 Silencing Inhibits Proliferation and Modulates Inflammatory and Apoptotic Markers in Testicular Germ Cell Tumors [0.03%]
沉默转谷氨酰胺酶7抑制增殖并调节睾丸生殖细胞肿瘤中的炎症和凋亡标志物
Rawabi S Altuwayjiri,Ibtesam S Almami
Rawabi S Altuwayjiri
Objective: Testicular germ cell tumors (TGCTs) represent the most common malignancy among young men aged 20-40 years. Transglutaminase 7 (TG7), encoded by TGM7, is a poorly characterized enzyme whose function in TGCT rema...
Khanh Toan Nguyen,Thi Huong Pham,Van Lam Ngo et al.
Khanh Toan Nguyen et al.
Objective: Patients with stage III non-small cell lung cancer (NSCLC) present with a heterogeneous disease profile and often require multifaceted treatment strategies. This research aimed to investigate the demographic fe...
Hiroshi Yoshida,Mayumi Kobayashi Kato
Hiroshi Yoshida
Ovarian endometrioid carcinoma (OEC) accounts for ~10% of epithelial ovarian cancers and displays broad morphologic diversity that complicates diagnosis and grading. Recent data show that the endometrial cancer molecular taxonomy (DNA polym...
Retraction: MicroRNA-181b Inhibits Cellular Proliferation and Invasion of Glioma Cells via Targeting Sal-Like Protein 4 [0.03%]
撤稿:MicroRNA-181b通过靶向Sal样蛋白4抑制胶质瘤细胞增殖和侵袭
Oncology Research Editorial Office
Oncology Research Editorial Office
[This retracts the article DOI: 10.3727/096504016X14791732531006.]. © 2025 The Author.