Intramedullary mesenchymal stromal cell transplantation in humans: Procedural safety and oncological risk reassessment [0.03%]
人源化髓内间质干细胞移植：操作安全性及肿瘤风险的再评估
Caroline Nonnarath,Nicolas Serratrice
Caroline Nonnarath
Intramedullary cellular transplantation within the human spinal cord has historically been regarded as a highly experimental intervention associated with substantial theoretical risk. However, cumulative clinical evidence progressively chal...
Tissue repair and donor-dependent immune responses after allogeneic skeletal muscle-derived cell sheet transplantation in a rat gastric ulcer model [0.03%]
同种异体骨骼肌来源细胞片移植修复大鼠胃溃疡及其免疫响应研究
Yuta Kawaguchi,Moeka Nakayama,Kengo Kanetaka et al.
Yuta Kawaguchi et al.
Cell transplantation using cell sheet technology is a promising regenerative approach that enables the delivery of a large number of viable cells while preserving cell-cell interactions and extracellular matrix. However, the clinical applic...
Short-course blinatumomab as a bridge-to-transplantation improves the survival of Ph-negative MRD-positive B-ALL [0.03%]
短程Blinatumomab作为移植前的桥梁治疗可改善Ph阴性MRD阳性B-ALL患者的预后
Xia Shao,Miao Zhang,Huiying Qiu et al.
Xia Shao et al.
Post-transplant relapse remains the chief therapeutic challenge in Ph-negative B cell acute lymphoblastic leukemia (Ph- B-ALL). This retrospective study evaluated whether short-course blinatumomab for measurable resident disease (MRD) eradi...
Transplantation of human umbilical mesenchymal stromal cells attenuates heart failure progression in a rat model [0.03%]
人脐带间充质干细胞移植减轻大鼠心力衰竭模型的心脏功能恶化
Chen-Yuan Hsiao,Jian-Hong Ye,Chang-Ching Yeh et al.
Chen-Yuan Hsiao et al.
Myocardial infarction (MI), mainly caused by coronary artery occlusion, remains a leading cause of death worldwide. Although many patients survive after emergency treatment, chronic MI often develops, underscoring the need for effective the...
Three-dimensionally printed mesoporous bioactive glass for craniomaxillofacial bone regeneration: Material evolution, functional mechanisms, and clinical translation [0.03%]
用于颅面骨再生的三维打印介孔生物活性玻璃：材料演变、功能机制及临床转化
Tianqi Wu,Yijie Du,Baofeng Yang et al.
Tianqi Wu et al.
Craniomaxillofacial (CMF) bone defects pose significant regenerative challenges due to complex anatomy and physiological demands. While autologous bone grafting remains the gold standard, it is limited by donor-site morbidity and supply con...
Hotspots and trends in stem cell therapy for ligament injuries: A bibliometric analysis (2001-2025) [0.03%]
干细胞治疗韧带损伤的热点和趋势（2001-2025）：基于文献计量学分析
Xuchao Wang,Junjie Liu,Wenlong Gao
Xuchao Wang
Ligament injuries can lead to lasting instability and early joint degeneration despite rehabilitation or surgery. Stem cell therapies may aid regeneration, but studies are highly variable. Bibliometric analysis can summarize trends, hotspot...
Amniotic epithelial cells enhance islet engraftment by suppressing early inflammation in intraportal transplantation [0.03%]
胎盘羊膜上皮细胞通过抑制肝脏内移植的早期炎症促进胰岛移植物的存活和功能改善
Kaoru Okada,Kazuaki Tokodai,Miyako Tanaka et al.
Kaoru Okada et al.
Amniotic epithelial cells (AECs) have immunomodulatory and anti-inflammatory properties that may improve outcomes in cell transplantation. However, their effect on islet engraftment after intraportal co-transplantation remains unclear. We e...
Cdc42-Modified BMSC-Derived exosomes promote acellular nerve allografts to bridge sciatic nerve defects [0.03%]
CDC42修饰的骨髓间充质干细胞源性外泌体促进同种异体脱细胞神经移植物修复坐骨神经缺损
Xin Sui,Guangming Dai,Bo Feng
Xin Sui
Peripheral nerve injury (PNI) often results in persistent functional deficits, and current treatments remain suboptimal. This study developed a tissue-engineered graft by integrating Cdc42-modified bone marrow-derived mesenchymal stem cell ...
Organ-on-a-chip as a next-generation tool in drug development: A bibliometric and patent analysis [0.03%]
器官芯片在药物研发中的下一代工具：文献计量和专利分析
Yue Du,Yang Xu,Pengxiang Tang et al.
Yue Du et al.
Organ-on-a-chip (OoC) platforms are microengineered systems that combine microfluidic control with living cells to emulate the physiological functions of human tissues and organs in vitro. OoC has become a transformative tool in pharmaceuti...
Isolation of functional human islets from pancreatectomy remnants: Determinants of yield and functionality [0.03%]
人胰腺切除残余组织中功能胰岛的分离：产量及功能的影响因素分析
Karl Herbert Hillebrandt,Theresa Lohmann,Luna Haderer et al.
Karl Herbert Hillebrandt et al.
Human pancreatic islets are essential for studies in β-cell biology, cell transplantation, and tissue engineering, yet access to viable human islets remains limited because conventional isolation protocols primarily rely on whole pancrease...