Feasibility of post-induction consolidation with BCMA CAR-T cell therapy in newly diagnosed multiple myeloma not proceeding to ASCT: A preliminary case series [0.03%]
Jiaying Wu,Rubing Zheng,Xi Ming et al.
Jiaying Wu et al.
B-cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cell therapy has demonstrated promising efficacy in relapsed/refractory multiple myeloma (MM). However, evidence supporting its use in earlier treatment settings remains lim...
Bohdan Karabinskyi,Svitlana Alkhimova,Olena Holembiovska
Bohdan Karabinskyi
This review examines how mechanical and chemical stimuli shape stem-cell behavior and how live-cell imaging combined with artificial intelligence can support the evaluation and optimization of 3D bioprinting workflows. Current evidence indi...
Downregulating ROCK2 by human umbilical cord mesenchymal stem cells promotes pro-resolving microglial polarization and alleviates cerebral injury in germinal matrix hemorrhage [0.03%]
人脐带间充质干细胞通过下调ROCK2促进 germinal matrix 出血后微胶质细胞向促消退型极化并改善脑损伤
Mengting Yang,Sha Wu,Jianwei Xu et al.
Mengting Yang et al.
To address the lack of effective treatments for germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH), a devastating condition in preterm infants with poor prognosis, this study investigated the neuroprotective potential and unde...
Extracellular vesicles secreted by adipose-derived stem cells alleviate dedifferentiation and senescence in monolayer-expanded chondrocytes by suppressing interleukin-1β-induced MAPK signaling [0.03%]
脂肪源性干细胞分泌的细胞外囊泡通过抑制IL-1β诱导的MAPK信号通路缓解单层扩增软骨细胞去分化和衰老
Shun-Cheng Wu,Ling-Hua Chang,Che-Wei Wu et al.
Shun-Cheng Wu et al.
Autologous chondrocyte implantation (ACI) has long been regarded as the gold-standard chondrocyte-based therapy for articular cartilage repair. The main challenge in ACI is that chondrocytes lose their chondrogenic phenotype after monolayer...
Xenopax from a real-world and economic perspective: The future of second-line treatment and prophylaxis for SR-aGVHD [0.03%]
从现实世界和经济角度看丁酸梭菌用于SR-aGVHD二线治疗及预防的未来方向
Yigeng Cao,Erlie Jiang
Yigeng Cao
Steroid-refractory acute graft-versus-host disease (SR-aGVHD) remains a major therapeutic challenge after allogeneic hematopoietic stem cell transplantation. Although ruxolitinib and basiliximab are widely used, their limitations highlight ...
Cryopreservation of hepatocytes: Impact of long-term storage and organ donor factors on cell quality for clinical applications [0.03%]
肝细胞的冷冻保存：长期储存和供体器官因素对临床应用的细胞质量的影响
Kadriye Güven,Valeria Iansante,Sharon C Lehec et al.
Kadriye Güven et al.
Liver transplantation is the only curative option for end-stage liver disease, but its applicability is limited by donor shortages. Hepatocyte transplantation offers a promising alternative, particularly for pediatric acute liver failure, y...
Evolution of mesenchymal stem cell therapies for traumatic brain injury: A decade of advances, mechanisms, and translational prospects [0.03%]
十年来间充质干细胞治疗创伤性脑损伤的发展、机制及转化前景
Peining Zhu,Yufei Gao
Peining Zhu
Traumatic brain injury (TBI) remains a major global health challenge with limited effective treatments. This systematic review documents the significant evolution of mesenchymal stem cell (MSC) therapies from traditional cell transplants to...
Total marrow irradiation-based conditioning for allogeneic hematopoietic stem cell transplantation in patients with hematologic malignancies: A multicenter real-world study [0.03%]
基于全身骨髓照射的allo-HSCT预处理方案治疗血液系统恶性肿瘤患者的多中心真实世界研究
Yi Zhang,Ran Zhang,Xiena Cao et al.
Yi Zhang et al.
Currently, there is very limited large-scale real-world data on the use of total marrow irradiation (TMI) as conditioning for allogeneic hematopoietic stem cell transplantation (allo-HSCT). The primary objective of this study was to evaluat...
Multicenter Study
Cell transplantation. 2026 Jan-Dec:35:9636897261440297. DOI:10.1177/09636897261440297 2026
The anti-inflammatory effects of mesenchymal stem cells and their research progress in hematopoietic stem cell transplantation: A comprehensive review [0.03%]
间充质干细胞的抗炎作用及其在造血干细胞移植中研究进展的综合述评
Changling Zhu,Shuai Ma,Wangfu Jiang et al.
Changling Zhu et al.
Hematopoietic stem cell transplantation (HSCT) is frequently accompanied by severe inflammation-related complications, among which graft-versus-host disease (GVHD) stands out as one of the most common and life-threatening. As a systemic inf...
Ultrasound-guided intrarenal arterial injection promotes homing of MSCs and recovery of kidney in Adriamycin-induced nephropathy in rats [0.03%]
超声引导下肾内动脉注射促进腺苷诱导的肾病大鼠间充质干细胞归巢及肾脏修复
Chunjuan Xia,Jiaping Wang,Xue Hu et al.
Chunjuan Xia et al.
To identify the optimal transplantation route for enhancing homing of mesenchymal stem cells (MSCs) to the kidney, thereby ameliorating rat Adriamycin nephropathy (AN). In vivo animal imaging revealed that ultrasound-guided intrarenal-arter...