Stem cell therapy for inherited retinal diseases: Trends and insights from 2000 to 2024 [0.03%]
遗传性视网膜疾病干细胞治疗：2000年到2024年的趋势与见解
Jinyi Long,Ziyang Xu,Ping Hu et al.
Jinyi Long et al.
Stem cell therapy has emerged as a promising strategy for inherited retinal diseases (IRDs), yet its global research trajectory has not been systematically mapped. This study analyzes publication trends, leading contributors, and thematic e...
From risk perception to action: A qualitative study of self-management in hematopoietic stem cell transplant patients [0.03%]
从风险感知到行动：血液干细胞移植患者的自我管理质性研究
Xiaoyan Yu,Zhizi Xiao,Xuee Li et al.
Xiaoyan Yu et al.
A descriptive qualitative study was conducted to explore risk perception, self-management challenges, and coping strategies among Chinese hematopoietic stem cell transplantation (HSCT) patients, using the Health Action Process Approach (HAP...
Enhancing female fertility by biomaterial-based regeneration of uterine tubes [0.03%]
基于生物材料的输卵管再生技术改善女性生育力
Martina Culenova,Maria Kleinova
Martina Culenova
Tubal factor infertility remains a major cause of female reproductive dysfunction. Current therapeutic options, such as surgical repair or in vitro fertilization, only bypass but do not restore the dysfunctional uterine tube. Recent advance...
Photobiomodulation-induced activation of Wnt signaling enhances differentiation of adipose-derived stem cells into tenocytes: Mechanistic insights into regenerative signaling pathways [0.03%]
光生物调节诱导Wnt信号激活促进脂肪源干细胞向腱细胞分化：再生信号通路的机制研究
Mbali Mpanza,Heidi Abrahamse,Anine Crous
Mbali Mpanza
The differentiation of adipose-derived stem cells (ADSCs) into tendon cells is a key process in tissue engineering and regenerative medicine. The Wnt signaling pathway plays a key role in regulating cell fate and tissue-regeneration decisio...
Bone marrow mesenchymal stem cells attenuate pain and modulate peripheral sodium channel activity in a rat model of complex regional pain syndrome type I [0.03%]
骨髓间充质干细胞减轻疼痛并调节复杂区域疼痛综合征Ⅰ型外周钠通道活性
Yuge Jiang,Kaikai Guo,Yi Liu et al.
Yuge Jiang et al.
Complex Regional Pain Syndrome Type I (CRPS-I) is a chronic neuropathic pain disorder characterized by peripheral nerve hyperexcitability and altered nociceptive signaling. Voltage-gated sodium channels (Nav1.7, Nav1.8, Nav1.9) in dorsal ro...
Long-term culture of human pancreatic islets reveals reduced metal ion pathways in their gene signature [0.03%]
人胰岛长期培养显示其基因特征中金属离子通路降低
Hiroyuki Kato,Tara K Sigdel,Mona Sheta et al.
Hiroyuki Kato et al.
Pancreatic islet transplantation is an effective therapy for type 1 diabetes; however, its broader clinical application is limited by the shortage of donors. Establishing long-term culture methods for isolated islets is an area of ongoing i...
Cell therapy for type 1 diabetes: Tracing historical progress and exploring emerging technologies [0.03%]
1型糖尿病的细胞治疗：追踪历史进展和探索新兴技术
Quentin Perrier,Sandrine Lablanche,Pierre-Yves Benhamou
Quentin Perrier
Type 1 diabetes remains an incurable autoimmune disease, and despite advances in insulin-delivery systems, many patients still face severe hypoglycemia, glucose variability, and psychological burden. Beta-cell replacement offers a transform...
Standardized dynamic glucose testing reveals donor-dependent heterogeneity in human islet function [0.03%]
标准化动态葡萄糖试验揭示人胰岛功能的供者依赖性异质性
Priyadarshini Gnanasekar,Chiara Saponaro,Markus Mühlemann et al.
Priyadarshini Gnanasekar et al.
Glucose-stimulated insulin secretion (GSIS) testing of isolated islets of Langerhans is crucial for assessing β-cell function, yet protocol variability complicates result interpretation. This study investigated insulin secretion heterogene...
Characterization of the intraspecies chimeric mouse brain at embryonic day 12.5 [0.03%]
胚胎12.5天的种内嵌合小鼠脑的特征分析
Phoebe Strell,Madison A Waldron,Sether T Johnson et al.
Phoebe Strell et al.
Incidence of neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis have increased dramatically as life expectancy has risen year-over-year, and can lead to neurologic changes. Neurologi...
Effects of bivalirudin on instant blood-mediated inflammatory reaction after intraportal islet transplantation [0.03%]
替尼卢丁对胰岛移植后瞬时血源性炎症反应的影响
Mei Liang,Peizhong Wu,Ziyuan Zhao et al.
Mei Liang et al.
The instant blood-mediated inflammatory reaction (IBMIR) is a major barrier to successful intraportal islet engraftment. Bivalirudin, a direct thrombin inhibitor, could mitigate IBMIR by suppressing thrombin activity and platelet activation...