Single-Cell Gene Expression Analysis Identifies Chronic Alcohol-Mediated Shift in Hepatocyte Molecular States After Partial Hepatectomy [0.03%]
单细胞基因表达分析揭示慢性酒精介导的部分肝切除术后肝细胞分子状态改变
Sirisha Achanta,Aalap Verma,Ankita Srivastava et al.
Sirisha Achanta et al.
The analysis of molecular states of individual cells, as defined by their mRNA expression profiles and protein composition, has gained widespread interest in studying biological phenomena ranging from embryonic development to homeostatic ti...
Therapeutic Efficacy of Vitamin D in Experimental c-MET-β-Catenin-Driven Hepatocellular Cancer [0.03%]
维生素D在c-MET-β-连环蛋白驱动的实验性肝细胞癌治疗中的疗效研究
Akiko Matsuda,Kaori Ishiguro,Irene K Yan et al.
Akiko Matsuda et al.
Aberrant activation of β-catenin signaling is frequently observed in hepatocellular cancer. Although Wnt/β-catenin signaling can be targeted by vitamin D, therapeutic use of vitamin D for this purpose is not currently established. We eval...
Biofabrication of Autologous Human Hepatocytes for Transplantation: How Do We Get There? [0.03%]
用于移植的自体人类肝细胞生物制造：我们如何实现？
Nandini Agarwal,Branimir Popovic,Nicole J Martucci et al.
Nandini Agarwal et al.
Directed differentiation of hepatocytes from induced pluripotent stem cells (iPSCs) holds promise as source material for treating some liver disorders. The unlimited availability of perfectly differentiated iPSC-derived hepatocytes will dra...