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期刊名:Autophagy

缩写:AUTOPHAGY

ISSN:1554-8627

e-ISSN:1554-8635

IF/分区:14.3/Q1

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共收录本刊相关文章索引4528
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Kangli Li,Xiangle Zhang,Dandan Dong et al. Kangli Li et al.
Senecavirus A (SVA) belongs to the picornaviruses and has emerged as a promising candidate for oncolytic virotherapy in humans. Understanding the immune suppression mechanisms employed by SVA can help optimize its therapeutic efficacy as an...
Ruixue Ai,Evandro F Fang Ruixue Ai
Autophagy preserves neuronal integrity by clearing damaged proteins and organelles, but its efficiency declines with aging and neurodegeneration. Depletion of the oxidized form of nicotinamide adenine dinucleotide (NAD+) is a hallmark of th...
Mikhail Rudinskiy,Maurizio Molinari Mikhail Rudinskiy
The lysosomal/vacuolar clearance of portions of organelles including the endoplasmic reticulum (ER), mitochondria, the Golgi apparatus and the nucleus, organellophagy, is mediated by autophagy receptors anchored at the surface of their resp...
Jiayi Lu,Damian N Di Florio,Patricia Boya et al. Jiayi Lu et al.
The human brain is one of the most metabolically active tissues in the body, due in large part to the activity of trillions of synaptic connections. Under normal conditions, macroautophagy/autophagy at the synapse plays a crucial role in sy...
Yong Hwan Kim,Joon Bum Kim,Ji-Eun Bae et al. Yong Hwan Kim et al.
Peroxisomes are essential for lipid metabolism and redox balance, with pexophagy playing a critical role in maintaining cellular homeostasis. However, the regulatory mechanisms of pexophagy remain unclear. Through functional screening, we i...
Xiaohui Zheng,Xiaotong Zhan,Shufei Tang et al. Xiaohui Zheng et al.
Macroautophagy/autophagy is a highly conserved pathway responsible for the bulk degradation of cytoplasmic material through the formation of a double-membrane structure known as the autophagosome. However, the precise mechanisms governing t...
Qi-Qiang Guo,Xiao-Yu Song,Liu Cao Qi-Qiang Guo
Mitochondrial reactive oxygen species (mtROS) are typically viewed as harmful byproducts of stress. However, our recent study establishes their fundamental role as essential signaling molecules that activate a protective adaptive response. ...
Tian Lan,Dantong Shang,Lan Lin et al. Tian Lan et al.
Mitochondrial nicotinamide adenine dinucleotide (NAD+) plays a central role in energy metabolism, yet its roles and mechanisms in mitophagy and innate immunity remain poorly understood. In this study, we identify mitochondrial NAD+ depletio...
Wanjun Tang,Bo Chen,Philip Wing-Lok Ho et al. Wanjun Tang et al.
Glioblastoma is the most aggressive form of primary brain malignancy and is defined as IDH/isocitrate dehydrogenase wild-type tumors. Upregulation of IDH1 is associated with poor prognosis; however, the mechanisms that regulate IDH1 express...