Correction notice [0.03%]
勘误通知书
Published Erratum
Autophagy. 2025 Dec 3:1. DOI:10.1080/15548627.2025.2597124 2025
Picornavirus VP2 protein suppresses innate immunity through selective autophagic degradation of IKBKE/IKKε [0.03%]
肠道病毒的VP2蛋白通过选择性自噬降解IKBKE抑制先天免疫反应
Kangli Li,Xiangle Zhang,Dandan Dong et al.
Kangli Li et al.
Senecavirus A (SVA) belongs to the picornaviruses and has emerged as a promising candidate for oncolytic virotherapy in humans. Understanding the immune suppression mechanisms employed by SVA can help optimize its therapeutic efficacy as an...
Ruixue Ai,Evandro F Fang
Ruixue Ai
Autophagy preserves neuronal integrity by clearing damaged proteins and organelles, but its efficiency declines with aging and neurodegeneration. Depletion of the oxidized form of nicotinamide adenine dinucleotide (NAD+) is a hallmark of th...
Mikhail Rudinskiy,Maurizio Molinari
Mikhail Rudinskiy
The lysosomal/vacuolar clearance of portions of organelles including the endoplasmic reticulum (ER), mitochondria, the Golgi apparatus and the nucleus, organellophagy, is mediated by autophagy receptors anchored at the surface of their resp...
Autophagy and mitophagy at the synapse and beyond: implications for learning, memory and neurological disorders [0.03%]
自噬和线粒体自噬在突触及其更广泛范围内的作用:对学习、记忆及神经障碍的影响
Jiayi Lu,Damian N Di Florio,Patricia Boya et al.
Jiayi Lu et al.
The human brain is one of the most metabolically active tissues in the body, due in large part to the activity of trillions of synaptic connections. Under normal conditions, macroautophagy/autophagy at the synapse plays a crucial role in sy...
Regulation of pexophagy by a novel TBK1-MARCHF7-PXMP4-NBR1 Axis in PEX1-depleted HeLa cells [0.03%]
PEX1缺陷HeLa细胞中由新发现的TBK1-MARCHF7-PXMP4-NBR1轴调节的胞嘧啶自噬作用
Yong Hwan Kim,Joon Bum Kim,Ji-Eun Bae et al.
Yong Hwan Kim et al.
Peroxisomes are essential for lipid metabolism and redox balance, with pexophagy playing a critical role in maintaining cellular homeostasis. However, the regulatory mechanisms of pexophagy remain unclear. Through functional screening, we i...
SH3P2-mediated autophagosomal targeting of the CCZ1-MON1-RABG3e module regulates autophagosome-vacuole fusion in Arabidopsis [0.03%]
SH3P2介导的自噬体CCZ1-MON1-RABG3e模块募集调节拟南芥中自噬体-液泡融合事件
Xiaohui Zheng,Xiaotong Zhan,Shufei Tang et al.
Xiaohui Zheng et al.
Macroautophagy/autophagy is a highly conserved pathway responsible for the bulk degradation of cytoplasmic material through the formation of a double-membrane structure known as the autophagosome. However, the precise mechanisms governing t...
Beyond the nucleus: the ATM-CHEK2 axis senses mtROS to orchestrate Mitophagy [0.03%]
线粒体DNA损伤修复机制及其在肿瘤发生中的作用研究进展
Qi-Qiang Guo,Xiao-Yu Song,Liu Cao
Qi-Qiang Guo
Mitochondrial reactive oxygen species (mtROS) are typically viewed as harmful byproducts of stress. However, our recent study establishes their fundamental role as essential signaling molecules that activate a protective adaptive response. ...
Mitochondrial NAD+-mediated mitophagy alleviates type I interferon response to the cytosolic mitochondrial dna [0.03%]
线粒体NAD+介导的线粒体自噬可缓解胞质线粒体DNA诱导的一型干扰素反应
Tian Lan,Dantong Shang,Lan Lin et al.
Tian Lan et al.
Mitochondrial nicotinamide adenine dinucleotide (NAD+) plays a central role in energy metabolism, yet its roles and mechanisms in mitophagy and innate immunity remain poorly understood. In this study, we identify mitochondrial NAD+ depletio...
Activation of chaperone-mediated autophagy suppresses glioblastoma by promoting wild-type IDH1/isocitrate dehydrogenase 1 degradation [0.03%]
激活分子伴侣介导的自噬可促进野生型IDH1/异柠檬酸脱氢酶1降解并抑制胶质母细胞瘤生成
Wanjun Tang,Bo Chen,Philip Wing-Lok Ho et al.
Wanjun Tang et al.
Glioblastoma is the most aggressive form of primary brain malignancy and is defined as IDH/isocitrate dehydrogenase wild-type tumors. Upregulation of IDH1 is associated with poor prognosis; however, the mechanisms that regulate IDH1 express...