Primary sporadic intracranial DICER1 mutant sarcoma with SSTR2 positivity in an adult patient mimicking anaplastic meningioma [0.03%]
一名成人患者原发性单发型颅内DICER1突变肉瘤伴SSTR2阳性，类似间变型脑膜瘤
Rachel L Welch,Rose S Fluss,Raquel T Yokoda et al.
Rachel L Welch et al.
Plasticity of synapses innervating spinal motor neurons after spinal cord injury in rhesus monkeys [0.03%]
猕猴脊髓损伤后支配脊髓运动神经元的突触可塑性
Ziyu He,Zhixian Liu,Wenjie Xu et al.
Ziyu He et al.
Patients with incomplete spinal cord injuries can experience partial recovery of motor function, a phenomenon believed to be linked to neural plasticity, as evidenced by numerous studies in rodent models. However, postinjury synaptic plasti...
FOXM1/CENPI axis regulation of proline and arginine metabolism in glioblastoma cells [0.03%]
FOXM1/CENPI轴调节胶质母细胞瘤细胞中的脯氨酸和精氨酸代谢
Meiling Weng,Xiaoping Zhu
Meiling Weng
Glioblastomas (GBMs) are common malignant brain tumors that currently lack effective therapies. Therefore, exploring potential molecular regulatory mechanisms is crucial for developing new treatment strategies. Centromeric protein I (CENPI)...
Establishment of normal myofiber size distribution in children and young adults [0.03%]
儿童和年轻人正常肌纤维大小分布的建立
Michael W Lawlor,Marta Margeta,Karra A Jones et al.
Michael W Lawlor et al.
Abnormalities of myofiber size are often of diagnostic significance on skeletal muscle biopsies, mainly when myofibers are excessively small. The establishment of standards for myofiber size in children has been hampered until recently by t...
Low-grade diffusely infiltrative tumor, SMARCB1-mutant: A diagnostic challenge-case report [0.03%]
低级别弥漫性浸润性肿瘤SMARCB1基因突变一例诊断分析
Takahiro Miyazaki,Yuhei Sangatsuda,Hirokazu Sugino et al.
Takahiro Miyazaki et al.
CBLN1 inhibits the inflammatory response by targeting GluD1 thereby alleviating resiniferatoxin-induced postherpetic neuralgia in mice [0.03%]
CBLN1通过靶向GluD1抑制炎症反应从而缓解树脂大戟诱导的小鼠带状疱疹后神经痛
Longji Cui,Xu Jia
Longji Cui
Postherpetic neuralgia (PHN) is a chronic, treatment-resistant pain condition following herpes zoster. Neuroinflammation plays a key role in its pathogenesis but the mechanisms are unclear. Cerebellin-1 (CBLN1), a synaptic protein of the C1...
FGFR1::TACC1 fusion in mixed-morphology pediatric glioneuronal tumors: Report of two cases [0.03%]
胶质神经元性肿瘤中FGFR1::TACC1融合：两例混合形态的儿科肿瘤报告
Erva Bengu Balaban Yilmaz,Nese Yeldir,Cansu Sonmez et al.
Erva Bengu Balaban Yilmaz et al.
Comprehensive benchmarking of deep learning approaches for automated astrocyte segmentation in traumatic brain injury [0.03%]
全面基准测试深度学习方法在创伤性脑损伤中进行星形胶质细胞分割的自动化
Amirhossein Bagherian,O F M Riaz Rahman Aranya,Allison Kosub et al.
Amirhossein Bagherian et al.
Astrocyte morphological changes and GFAP upregulation are hallmarks of traumatic brain injury (TBI) and quantifying these alterations in tissues is essential for assessing TBI severity and progression. However, conventional segmentation met...
Rapid assessment of MGMT promoter methylation status by droplet digital polymerase chain reaction on intraoperative smear preparation: A proof-of-concept study [0.03%]
基于术中涂片的液滴式数字聚合酶链反应快速评估MGMT启动子甲基化状态：概念验证性研究
Zachary Coty-Fattal,Heather Smith,Matthew McCord et al.
Zachary Coty-Fattal et al.
MGMT promoter methylation is an important predictor of response to chemotherapy in adult-type diffuse gliomas. Currently, MGMT promoter methylation assessment requires formalin-fixed, paraffin-embedded (FFPE) tissue. We developed a droplet ...
Tumor-associated macrophages in feline meningiomas: Exploring their prognostic significance [0.03%]
猫脑膜瘤相关的肿瘤相关巨噬细胞：探索其预后意义
Maria Teresa Mandara,Giuseppe Giglia,Greta Benedetti et al.
Maria Teresa Mandara et al.
Tumor-associated macrophages (TAMs) are the predominant immune cells in the tumor microenvironment (TME) of human meningiomas. They exhibit different functional phenotypes that contribute either to an anti-inflammatory and anti-tumor respon...