SARS-CoV-2 encoded ORF3a interacts with YY1 to promote latent HCMV reactivation [0.03%]
SARS-CoV-2.ORF3a通过与YY1蛋白相互作用促进潜伏HCMV再活化
Sisi Xia,Xiaoping Huo,Nanfang Liu et al.
Sisi Xia et al.
Human Cytomegalovirus (HCMV) is a commonly infected double-stranded DNA virus of the β-herpesviridae subfamily that typically establishes lifelong latency or persistent infection following primary infection. The regulation of HCMV latency ...
Host environment shapes filarial parasite fitness and Wolbachia endosymbionts dynamics [0.03%]
宿主环境影响丝虫寄生虫的适应度及沃尔巴克氏体内共生菌的动力学变化
Frédéric Fercoq,Clément Cormerais,Estelle Remion et al.
Frédéric Fercoq et al.
Filarial nematodes, responsible for diseases like lymphatic filariasis and onchocerciasis, depend on symbiotic Wolbachia bacteria for reproduction and development. Using the Litomosoides sigmodontis rodent model, we investigated how host ty...
Role of individual and population heterogeneity in shaping dynamics of multi-pathogen shedding in an island endemic bat [0.03%]
个体和群体异质性在岛屿特有种蝙蝠多病原体排放动力学中的作用
Samantha Aguillon,Magali Turpin,Gildas Le Minter et al.
Samantha Aguillon et al.
Understanding processes driving pathogen transmission in bats is critical to prevent spillovers and emergence events. Although substantial research has addressed this topic, few studies have directly examined shedding dynamics (as opposed t...
Xue Li,Xueping Zhou,Fangfang Li
Xue Li
Pelota, a conserved ribosome rescue factor involved in mRNA surveillance, has emerged as a pivotal player in host-virus arms race. Beyond its canonical role in maintaining translational fidelity via No-Go Decay and Non-Stop Decay pathways, ...
Correction: Brucella modulates secretory trafficking via multiple Type IV secretion effector proteins [0.03%]
订正：布鲁氏菌通过多种IV型分泌效应蛋白调控分秘转运路径
Sebenzile Myeni,Robert Child,Tony W Ng et al.
Sebenzile Myeni et al.
[This corrects the article DOI: 10.1371/journal.ppat.1003556.]. Copyright: © 2025 Myeni et al. This is an open access article distributed under the term...
Published Erratum
PLoS pathogens. 2025 Jul 10;21(7):e1013302. DOI:10.1371/journal.ppat.1013302 2025
Chi Li,Chengwei Yang,Jianbin Lai
Chi Li
Polyclonal B cells acquire LCMV antigens in a GP1-dependent manner [0.03%]
多克隆B细胞以GP1依赖的方式获得淋巴细脉络丛病毒抗原
Gabriel Chamberlain,Guillaume L Lopez,Léa Bourguignon et al.
Gabriel Chamberlain et al.
The polyclonal, T-dependent nature of hypergammaglobulinemia during murine infection with LCMV is well defined, however the mechanism by which polyclonal B cells acquire antigens for presentation remains unknown. Here we use LCMV-specific C...
HIV-1 Vpr orchestrates ciTRAN upregulation through TGF-β induction [0.03%]
HIV-1蛋白Vpr通过诱导转化生长因子β来调控ci_TRAN的上调
Aditi Choudhary,Katyayani Mallick,Rishikesh Dalavi et al.
Aditi Choudhary et al.
Circular RNA (circRNA) expression is widespread in immune cells infected by HIV-1, but the crosstalk between circRNA expression and various cellular signaling pathways remains elusive. Here, we report that HIV-1 Vpr can induce the productio...
Interleukin-17A signaling promotes CD8+ T cell cytotoxicity against West Nile virus infection through enhancing PI3K-mTOR-mediated metabolism [0.03%]
白细胞介素17A信号通过增强PI3K-mTOR介导的代谢促进CD8+t细胞对西尼罗病毒的细胞毒性作用
Farzana Nazneen,Biswas Neupane,Yao Chen et al.
Farzana Nazneen et al.
West Nile Virus (WNV), a mosquito-borne neurotropic flavivirus, is a major cause of viral encephalitis in the United States, posing a continuous threat to public health. Unfortunately, no vaccine or specific therapeutic intervention is avai...
Human herpesvirus 6B glycoprotein B postfusion structure, vulnerability mapping, and receptor recognition [0.03%]
人疱疹病毒6B融合后糖蛋白B结构、弱点图谱和受体识别机制
Chu Xie,Xin-Yan Fang,Yuan-Tao Liu et al.
Chu Xie et al.
Human herpesvirus 6B (HHV-6B), a β-herpesvirus that significantly threatens immunocompromised individuals, currently lacks targeted antiviral therapies or vaccines. Glycoprotein B (gB), the primary mediator of membrane fusion during viral ...