Seoul orthohantavirus evades innate immune activation by reservoir endothelial cells [0.03%]
首尔汉坦病毒通过感染宿主血管内皮细胞时逃避免疫激活
Stefan D Klimaj,Autumn LaPointe,Kimberly Martinez et al.
Stefan D Klimaj et al.
Pathogenic hantaviruses are maintained world-wide within wild, asymptomatic rodent reservoir hosts, with increasingly frequent human spillover infections resulting in severe hemorrhagic fever or cardio-pulmonary disease. With no approved th...
N6-methyladenosine RNA modification promotes Severe Fever with Thrombocytopenia Syndrome Virus infection [0.03%]
N6-甲基腺苷RNA修饰促进严重发热性伴血小板减少综合征病毒感染
Zhiqiang Chen,Jinyu Zhang,Jun Wang et al.
Zhiqiang Chen et al.
Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV), a novel bunyavirus primarily transmitted by Haemaphysalis longicornis, induces severe disease with a high mortality rate. N6-methyladenosine (m6A) is a prevalent internal chemical m...
Shengjie Weng,Erjie Tian,Meng Gao et al.
Shengjie Weng et al.
Eimeria is an intracellular obligate apicomplexan parasite that parasitizes the intestinal epithelial cells of livestock and poultry, exhibiting strong host and tissue tropism. Parasite-host interactions involve complex networks and vary as...
Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin [0.03%]
特非那丁使多重耐药的阿氏不动杆菌对多粘菌素敏感
Fabiana Bisaro,Clay D Jackson-Litteken,Jenna C McGuffey et al.
Fabiana Bisaro et al.
Acinetobacter baumannii causes life-threatening infections that are becoming difficult to treat due to increasing rates of multi-drug resistance (MDR) among clinical isolates. This has led the World Health Organization and the CDC to catego...
SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation [0.03%]
SARS-CoV-2进化在N蛋白磷酸化的作用之间取得平衡
Abdullah M Syed,Alison Ciling,Irene P Chen et al.
Abdullah M Syed et al.
All lineages of SARS-CoV-2, the coronavirus responsible for the COVID-19 pandemic, contain mutations between amino acids 199 and 205 in the nucleocapsid (N) protein that are associated with increased infectivity. The effects of these mutati...
Massive entry of BK Polyomavirus induces transient cytoplasmic vacuolization of human renal proximal tubule epithelial cells [0.03%]
BK多瘤病毒的大规模进入可诱导人肾近端小管上皮细胞暂时性胞浆空泡化
Elias Myrvoll Lorentzen,Stian Henriksen,Christine Hanssen Rinaldo
Elias Myrvoll Lorentzen
BK polyomavirus (BKPyV) is a ubiquitous human virus that establishes a persistent infection in renal tubular epithelial cells and mainly causes disease in kidney transplant recipients. The closely related simian polyomavirus SV40 is known t...
Bipolaris or Curvularia? Resolving the spicy issue of how clinical isolates should be reported [0.03%]
二點黴菌还是曲彎黴菌？临床分离菌株该如何报告的辣眼睛问题该解决了
Sarah E Kidd,Lars F Westblade
Sarah E Kidd
TMPRSS2 in microbial interactions: Insights from HKU1 and TcsH [0.03%]
TMPRSS2在微生物相互作用中的作用：来自HKU1和TcsH的见解
Zhengyang Pan,Daoqun Li,Leiliang Zhang
Zhengyang Pan
Transmembrane Serine Protease 2 (TMPRSS2), known primarily for its role as a protease, has emerged as a critical receptor for microbial agents such as human coronavirus HKU1 and exotoxin TcsH. HKU1 utilizes both sialoglycan and TMPRSS2 for ...
Enterovirus A71 and coxsackievirus A6 circulation in England, UK, 2006-2017: A mathematical modelling study using cross-sectional seroprevalence data [0.03%]
英国英格兰2006年至2017年肠道病毒A71和柯萨奇病毒A6的流行：基于横断面血清学数据的数学建模研究
Everlyn Kamau,Ben Lambert,David J Allen et al.
Everlyn Kamau et al.
Enterovirus A71 (EV-A71) and coxsackievirus A6 (CVA6) primarily cause hand, foot and mouth disease and have emerged to cause potential fatal neurological and systemic manifestations. However, limited surveillance data collected through pass...
Sustained immune activation and impaired epithelial barrier integrity in the ectocervix of women with chronic HIV infection [0.03%]
慢性HIV感染女性宫颈部持续免疫激活和上皮屏障功能障碍
Mathias Franzén Boger,Tyra Hasselrot,Vilde Kaldhusdal et al.
Mathias Franzén Boger et al.
Chronic systemic immune activation significantly influences human immunodeficiency virus (HIV) disease progression. Despite evidence of a pro-inflammatory environment in the genital tract of HIV-infected women, comprehensive investigations ...