Clàudia Soriano-Tordera,Jaime Buigues,Adrià Viñals et al.
Clàudia Soriano-Tordera et al.
The zoonotic transmission of bat coronaviruses poses a threat to human health. However, the diversity of bat-borne coronaviruses remains poorly characterized in many geographical areas. Here, we recovered eight coronavirus genomes by perfor...
Screening of different species reveals cat hepatocytes support HBV infection [0.03%]
不同物种的筛选实验表明猫肝细胞支持乙肝病毒复制
Zaichao Xu,Kaitao Zhao,Jingjing Wang et al.
Zaichao Xu et al.
Hepatitis B virus (HBV) remains a major public health challenge, with nearly 300 million chronic infections, yet research is hindered by the lack of suitable animal models. This study aimed to identify HBV-susceptible species and establish ...
Mapping Bornavirus encephalitis-A comparative study of viral spread and immune response in human and animal dead-end hosts [0.03%]
博纳病毒性脑炎的发病机制-人类和动物死胡同宿主中病毒传播及免疫反应的比较研究
Yannik Vollmuth,Nicola Jungbäck,Przemyslaw Grochowski et al.
Yannik Vollmuth et al.
Borna disease virus 1 (BoDV-1) has long been recognized as a cause of fatal encephalitis in animals and was only recently identified as a zoonotic pathogen causing a similar disease in humans. This study provides the first comprehensive com...
Two-pore channels in MR1-dependent presentation of Mycobacterium tuberculosis infection [0.03%]
MR1依赖的结核杆菌感染呈递过程中的双孔通道蛋白的作用
Elham Karamooz,Se-Jin Kim,Jessie C Peterson et al.
Elham Karamooz et al.
MR1 is a ubiquitously expressed MHC-Ib molecule that presents microbial metabolites to MR1-restricted T cells, but there are differences in the antigen presentation pathway of an intracellular microbe compared to exogenously delivered antig...
Cell type differences in human cytomegalovirus transcription and epigenetic regulation with insights into major immediate-early enhancer-promoter control [0.03%]
人巨细胞病毒转录和表观遗传调控的细胞类型差异及对主要早期增强子-启动子控制的见解
Qiaolin Hu,Ming Li,Mrutyunjaya Parida et al.
Qiaolin Hu et al.
Cell type differences in the human cytomegalovirus (HCMV) transcriptome may arise from variations in transcription or post-transcription regulation. Here we report unexpected differences in transcription and epigenetic control in late-stage...
Correction: Antibody-mediated spike activation promotes cell-cell transmission of SARS-CoV-2 [0.03%]
关于抗体介导的刺突激活促进SARS-CoV-2细胞间传播的更正通知
PLOS Pathogens Staff
PLOS Pathogens Staff
[This corrects the article DOI: 10.1371/journal.ppat.1011789.]. Copyright: © 2025 The PLOS Pathogens Staff. This is an open access article distributed u...
Published Erratum
PLoS pathogens. 2025 Aug 4;21(8):e1013394. DOI:10.1371/journal.ppat.1013394 2025
NK cell-macrophage interactions in granulomas correlate with limited tuberculosis pathology [0.03%]
肉芽肿中的自然杀伤细胞-巨噬细胞相互作用与限制性结核病病理有关
Paula Niewold,Marieke E IJsselsteijn,Karin Dijkman et al.
Paula Niewold et al.
Development of novel vaccines and treatment approaches against tuberculosis are hampered by limited knowledge of what constitutes a protective immune response against Mycobacterium tuberculosis (Mtb). Granulomas are organized immune aggrega...
From darkness to light: Genetic manipulation of an atypical plant virus unveils key insights into kitavirus biology, highlighting capsid protein and eIF4A engagement to drive viral infection [0.03%]
从黑暗到光明：植物病毒的非典型基因操作揭示了Kitavirus生物学的关键见解，强调衣壳蛋白和eIF4A结合以驱动病毒感染
Mikhail Oliveira Leastro,Elliot Watanabe Kitajima,Vicente Pallas et al.
Mikhail Oliveira Leastro et al.
Kitaviridae, a newly recognized virus family, includes plant viruses infecting crops of great global importance, notably citrus. Despite its significant impact on citrus agricultural production, the molecular mechanisms underlying kitavirus...
Search for a genetic cause of variably protease-sensitive prionopathy [0.03%]
寻找可变型早老素蛋白酶敏感性普里昂病的遗传原因
Yuan Lian,Keisi Kotobelli,Stacey Hall et al.
Yuan Lian et al.
Variably protease-sensitive prionopathy (VPSPr) is a rare, atypical subtype of prion disease currently classified as sporadic. We performed exome sequencing and targeted sequencing of PRNP non-coding regions on genomic DNA from autopsy-conf...
MAP3K15 facilitates multiple viral genes expression in crustaceans via Dorsal-CC-CL-STAT axis besides the JNK/P38 pathway [0.03%]
MAP3K15通过Dorsal-CC-CL-STAT轴促进甲壳动物多种病毒基因表达（不仅包括JNK/P38途径）
Xiao-Qin Ran,Chen-Chen Liu,Xue-Mei Xu et al.
Xiao-Qin Ran et al.
The mitogen-activated protein kinase (MAPK) pathway is a conserved signaling system that responds to extracellular signals and translates them into appropriate cellular responses. While multiple MAPK kinase kinases (MAP3Ks) play a crucial r...