Transcriptional factor ATF3 impairs KSHV lytic replication by suppressing the expression of viral bZIP protein K8 [0.03%]
转录因子ATF3通过抑制病毒bZIP蛋白K8的表达来阻碍卡波氏肉瘤疱疹病毒的潜伏病毒激活
Jiazhen Dong,Xiaowei Liang,Yuncai Chen et al.
Jiazhen Dong et al.
Kaposi's Sarcoma-associated herpesvirus (KSHV) is a human gamma herpesvirus, establishing two different phases in its life cycle, latent infection and lytic replication. KSHV-encoded basic leucine zipper (bZIP) family of protein K8 (also ca...
Correction: An atypical F-type ATPase is necessary for the function of the antibody cleavage system MIB-MIP in mycoplasmas [0.03%]
订正：非典型F型ATP酶是支原体抗体切割系统MIB-MIP功能所必需的成分
PLOS Pathogens Editors
PLOS Pathogens Editors
[This corrects the article DOI: 10.1371/journal.ppat.1014043.]. Copyright: © 2026 The PLOS Pathogens Editors. This is an open access article distributed...
Published Erratum
PLoS pathogens. 2026 May 11;22(5):e1014203. DOI:10.1371/journal.ppat.1014203 2026
SPRY domains encode ubiquitin ligase specificity for ZAP and RIG-I [0.03%]
spry结构域编码zap和rig-i的泛素连接酶特异性
Ibrahim Syed,Sheng Chen,David J Peeler et al.
Ibrahim Syed et al.
Innate immune sensors rely on ubiquitin ligases to calibrate antiviral responses, yet the rules governing substrate recognition by SPRY-containing ligases remain poorly defined. Here, we establish a large-scale structure-based screening pip...
How post-translational modifications in pathogenic fungi inform pathogenesis and immune responses [0.03%]
病原真菌的翻译后修饰在致病性和免疫反应中的作用机制研究
Satya Ranjan Sahu,Charles A Specht,Stuart M Levitz
Satya Ranjan Sahu
An IL-1, IL-17, and IL-22 cytokine circuit controls vulvovaginal candidiasis independently of estrogen [0.03%]
独立于雌激素的IL-1、IL-17和IL-22细胞因子回路控制外阴阴道念珠菌病
Bianca M Coleman,Melissa E Cook,Md Robin Khan et al.
Bianca M Coleman et al.
Vulvovaginal candidiasis (VVC) affects >75% of women, with considerable morbidity and high medical cost burden. While Type 17 cytokines (IL-17, IL-22) are critical for oral and dermal immunity to C. albicans, their role in VVC has been less...
Weak selection and stochastic processes limit the emergence of antigenic variants during household transmission of influenza A viruses [0.03%]
弱选择和随机效应限制了流感病毒在家庭内传播过程中抗原变体的出现
Hunter J Ries,Joseph Lalli,Kelsey R Florek et al.
Hunter J Ries et al.
Influenza viruses undergo antigenic drift, the gradual accumulation of mutations that cause antigenic changes in the viral surface proteins hemagglutinin (HA) and neuraminidase (NA). Although selection for antigenic variants is detectable o...
Wolbachia-induced Cytoplasmic Incompatibility drives epigenetic and maternally-influenced post-embryonic defects [0.03%]
wolbachia诱导的细胞质不相容性引起表观遗传和母体影响的胚胎后缺陷
Claire Perez,Jillian Porter,Brandt Warecki et al.
Claire Perez et al.
A common form of Wolbachia-induced manipulation of host reproduction is Cytoplasmic Incompatibility (CI). In CI, Wolbachia modification of sperm results in pronounced defects in paternal chromosome condensation, replication, and segregation...
Tracking fungal pathogens on cancer: Oncomicrobes or opportunistic bystanders? [0.03%]
追踪癌症上的真菌病原体：肿瘤微生物还是机会性共生者？
Rosana Alves,Wouter Van Genechten,Patrick Van Dijck
Rosana Alves
Human herpesvirus 7 integrates into host telomeres via its telomeric repeat arrays [0.03%]
人疱疹病毒7通过其端粒重复序列整合到宿主端粒上
Yingnan Cheng,Joilson Xavier,Dusan Kunec et al.
Yingnan Cheng et al.
Human herpesvirus 7 (HHV-7) is a ubiquitous betaherpesvirus and a causative agent of roseola infantum. HHV-7 harbors telomeric repeat arrays (TMR) identical to human telomeres at the ends of its genome. While similar repeats contribute to h...
Globodera pallida virulence on major potato resistance has a common genetic basis across Western Europe [0.03%]
欧洲各地 Potato rotlinvirus 对主要马铃薯抗性的作用具有共同的遗传基础
Arno S Schaveling,Leidy van Rijt,Yoonseon Do et al.
Arno S Schaveling et al.
The potato cyst nematode Globodera pallida poses a major threat to potato production in Western Europe. Current management strategies largely depend on the use of potato varieties carrying the genetic resistance GpaVvrn. However, reports fr...