Paula Ortega-López,Javier Diéguez-Uribeondo
Paula Ortega-López
Anti-malarial contact dependent blocking of transmission of Plasmodium vivax by Anopheles darlingi mosquito vector [0.03%]
达灵格蚊作为媒介阻止间日疟原虫传播的接触依赖性抗疟作用
Jéssica E A Kassupá,Alice O Andrade,Alessandra S Bastos et al.
Jéssica E A Kassupá et al.
Malaria, caused by protozoa of the genus Plasmodium and transmitted to humans through the bite of mosquitoes of the genus Anopheles, remains a public health problem. Long-Lasting Insecticide -treated Bed Nets (LLINS) and Indoor Residual Spr...
A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss [0.03%]
Pink1敲除和野生型小鼠单次感染Citrobacter rodentium后出现血脑屏障局部受损、微胶质细胞活化受限但多巴胺神经元轴突末端不丢失
Sriparna Mukherjee,Vladimir Grouza,Alex Tchung et al.
Sriparna Mukherjee et al.
A growing body of research suggests a link between immune system activation and the development of Parkinson's disease (PD). Previous work showed that repeated gastrointestinal infection with Citrobacter rodentium can induce PD-like motor d...
Correction: Structural basis for substrate recognition and inhibition of thioredoxin glutathione reductase from Schistosoma japonicum: Implications for antiparasitic development [0.03%]
关于斯氏曼森血吸虫硫氧还蛋白谷胱甘肽还原酶底物识别及抑制的结构基础的更正：对开发抗寄生虫药物的意义
Songqing Wang,Wenbin Hong,Shukun Zhong et al.
Songqing Wang et al.
[This corrects the article DOI: 10.1371/journal.ppat.1014125.]. Copyright: © 2026 Wang et al. This is an open access article distributed under the terms...
Published Erratum
PLoS pathogens. 2026 Jun 30;22(6):e1014386. DOI:10.1371/journal.ppat.1014386 2026
Balancing under constraint: Structural insights into norovirus evolution and antigenic innovation [0.03%]
受约束下的平衡：诺如病毒进化及抗原创新的结构见解
Yun Chen,Xin-Zi Wang,Ying-Yu Tan et al.
Yun Chen et al.
Norovirus is the leading cause of acute viral gastroenteritis worldwide. While genomic studies have revealed its diversity and evolutionary patterns, the structural mechanisms driving viral adaptation remain poorly understood. Here, we esta...
Cyclic AMP compartmentalization drives signal specificity to control vector colonization and mammalian host infection by American trypanosomes [0.03%]
环磷酸腺苷隔室化驱动信号特异性以控制美洲锥虫的载体定殖和哺乳动物宿主感染
Milad Ahmed,Joshua Carlson,Asima Das et al.
Milad Ahmed et al.
Cyclic AMP (cAMP) signaling is crucial for environmental sensing and response to stress conditions in trypanosomatids. However, the mechanisms driving the specificity of cAMP signals remain poorly understood in these protozoan parasites. We...
The human parasite, Toxoplasma gondii, is paralyzed without two components of the apical polar ring [0.03%]
新寄生虫病疗法研究获进展
Jonathan Munera Lopez,Luisa F Arias Padilla,Isadonna F Tengganu et al.
Jonathan Munera Lopez et al.
The phylum Apicomplexa contains ~ 6000 known species of unicellular eukaryotic parasites. A unifying feature among the apicomplexans is the apical complex, which varies in complexity in different lineages, but always contains an annulus (a....
Dissecting the host determinants of orthoflavivirus infection using QIC-seq [0.03%]
利用QIC-seq解析正黄病毒属感染的宿主决定因素
Allison J Dupzyk,Benjamin S Waldman,James Zengel et al.
Allison J Dupzyk et al.
Orthoflaviviruses are genetically related, yet cause distinct disease patterns ranging from hepatitis and vascular shock syndrome to encephalitis and congenital abnormalities. There is an incomplete understanding of the cellular pathways co...
Active but not passive passengers: Persistent-propagative plant viruses manipulate insect vectors for efficient transmission [0.03%]
主动而不被动的宿主：持久性植物病毒操控昆虫介体以实现高效传播
De-Shui Liu,Dong-Min Gao,Xian-Bing Wang et al.
De-Shui Liu et al.
Most plant viruses rely on insect vectors for transmission. In general, nonviruliferous vectors acquire viruses from infected plants, whereas viruliferous vectors subsequently move to uninfected plants for virus inoculation. However, they a...
Endogenous viral elements trace the ancient origins and early evolution of the Caulimoviridae [0.03%]
内源病毒元件追溯 caulimoviridae 的古起源和早期进化
Héléna Vassilieff,Saad Serfraz,Nathalie Choisne et al.
Héléna Vassilieff et al.
Endogenous viral elements (EVEs) are viral sequences integrated into host genomes, functioning as molecular fossils of past infections. Most characterised EVEs in plants are derived from the Caulimoviridae, the only family of dsDNA viruses ...