The Bunyamwera orthobunyavirus Gc glycoprotein head and stalk drives an infectious virion assembly pathway specific for the insect host [0.03%]
布尼雅梅拉正粘病毒Gc糖蛋白头部和茎部驱动一种特定于昆虫宿主的感染性病毒组装途径
Amelia B Shaw,Hiu Nam Tse,Molly V Durawa et al.
Amelia B Shaw et al.
The Orthobunyavirus genus of arthropod-borne segmented RNA viruses comprises important pathogens including the human-infecting Oropouche virus and ruminant-infecting Schmallenberg virus (SBV). The prototypical Bunyamwera orthobunyavirus (BU...
The hidden costs of using media to mimic the hosts of Fusarium graminearum: An epigenetic perspectives [0.03%]
从表观遗传学角度探讨棒孢镰刀菌效应蛋白真核表达体系的隐性成本
Jade F Smith,Hans-Wilhelm Nuetzmann,Martin Darino et al.
Jade F Smith et al.
Pathogens dynamically reprogrammed gene expression when transitioning between nonhost and host environments. Epigenetic regulation can provide a rapid and reversible mechanism for this shift. Using published data from Shao et al. (2024) and...
Japanese encephalitis virus hijacks the host purine biosynthetic network to promote viral replication in neurons [0.03%]
japanese encephalitis病毒劫持宿主嘌呤代谢网络促进病毒感染神经元的复制
Jun Gu,Chencheng Fan,Shengxian Xiang et al.
Jun Gu et al.
Japanese encephalitis virus (JEV) is an important neurotropic orthoflavivirus that poses a threat to both human and animal health. However, the mechanism underlying its rapid replication in the central nervous system (CNS) remains poorly un...
Naturally occurring mutations in replication proteins of a small RNA virus that alter the number, sizes, and relative abundances of subgenomic RNAs [0.03%]
存在于复制蛋白的小RNA病毒的自然突变改变了亚基因组RNA的数量、大小和相对丰度
Camila Perdoncini Carvalho,Deya Wang,Junping Han et al.
Camila Perdoncini Carvalho et al.
Many positive-strand (+) RNA viruses produce subgenomic RNAs (sgRNAs) in infected cells. sgRNAs are synthesized by virus-encoded replication proteins (RPs), but whether RPs regulate the number and sizes of sgRNAs remains largely unknown. We...
Subversion of the salicylic acid signaling pathway by the bipartite begomoviral protein BV1 promotes virus infection and vector preference to virus-infected plants [0.03%]
双部件贝洛病毒蛋白BV1通过扰乱水杨酸信号途径促进病毒感染和介体更偏好感染病毒的植株
Guan-Ping Chen,Di Li,Xing Zhang et al.
Guan-Ping Chen et al.
The outbreak of vector-borne plant viruses entails both efficient in planta virus infection and productive vector-mediated transmission. Yet, the factors that concurrently regulate these two key viral traits remain understudied. Here we exa...
A rotavirus vaccine candidate attenuated by codon deoptimization protects neonatal mice against wild-type virus infection [0.03%]
一种利用密码子去优化技术弱化的轮状病毒疫苗候选株可保护新生小鼠免受野毒株的感染
Zelin Chen,Tomohiro Kotaki,Daisuke Motooka et al.
Zelin Chen et al.
Rotavirus infection is a leading cause of acute viral gastroenteritis and diarrhea in infants and young children. Owing to the limited development of effective antiviral therapies, vaccination has become the primary and most efficient strat...
Staphylococcus aureus rewires arginine metabolism to drive mammary aging via macrophage-epithelial crosstalk [0.03%]
金黄色葡萄球菌通过巨噬细胞上皮相互作用重塑精氨代谢以促进乳腺衰老
Yuhang Jin,Kai Yang,Ruoxi Sun et al.
Yuhang Jin et al.
As a common opportunistic pathogen, Staphylococcus aureus (S. aureus) can rapidly adapt to the host immune system and cause chronic infections. Currently, such chronic infections are extremely difficult to eliminate, severely impairing the ...
Correction: Staphylococcus aureus adapts to the host nutritional environment by coordinating the activity of central metabolic enzymes [0.03%]
订正：金黄色葡萄球菌通过协调中央代谢酶的活性来适应宿主营养环境
PLOS Pathogens Staff
PLOS Pathogens Staff
[This corrects the article DOI: 10.1371/journal.ppat.1014183.]. Copyright: © 2026 The PLOS Pathogens Staff. This is an open access article distributed u...
Published Erratum
PLoS pathogens. 2026 Jul 6;22(7):e1014398. DOI:10.1371/journal.ppat.1014398 2026
Correction: Early antiretroviral therapy in SIV-infected rhesus macaques reveals a multiphasic, saturable dynamic accumulation of the rebound competent viral reservoir [0.03%]
纠正：早期抗逆转录病毒治疗感染了猴免疫缺陷病毒的恒河猴显示回弹能力病毒储存库多阶段动态积累饱和性
PLOS Pathogens Staff
PLOS Pathogens Staff
[This corrects the article DOI: 10.1371/journal.ppat.1012135.]. Copyright: © 2026 The PLOS Pathogens Staff. This is an open access article distributed u...
Published Erratum
PLoS pathogens. 2026 Jul 6;22(7):e1014399. DOI:10.1371/journal.ppat.1014399 2026
RNF31 restricts EV-A71 replication through innate immune activation and VP4 degradation, and is antagonized by viral 3C proteases [0.03%]
RNF31通过先天免疫激活和VP4降解限制EV-A71复制，并被病毒3C蛋白酶拮抗
Qingxiang Zhang,Yuan Gao,Wenying Gao et al.
Qingxiang Zhang et al.
A persistent evolutionary arms race exists between enteroviruses and their hosts, in which viruses employ multiple strategies to antagonize host antiviral defenses and sustain efficient replication. However, how host restriction factors are...