Valentin Madyarov,Marat Kuzikeev,Maulen Malgazhdarov et al.
Valentin Madyarov et al.
Objectives: The purpose of this study is to analyse the effectiveness of methods of diagnosis and treatment of patients with acute intestinal obstruction. ...
Blood pressure lowering effects of Vernonia amygdalina Del. Aqueous fraction on hypertensive Wistar Kyoto rats [0.03%]
Vernonia amygdalina Del. 水提液对高血压Wistar Kyoto大鼠的降压作用研究
Dian Ayu Juwita,Rindang Farinka,Rahmad Abdillah et al.
Dian Ayu Juwita et al.
Objectives: Vernonia amygdalina (VA) is a plant that consumed as vegetable by Indonesians contained numerous secondary metabolites. VA's pharmacological action, including its antioxidant properties, anticancer, antidiabet...
Comparative effectiveness is the common denominator in health services research: experimental effects are promising, real-world effects are compelling [0.03%]
效果比较是卫生服务研究的共同要素：实验效果很有前景，现实世界的效应非常有说服力
Franz Porzsolt
Franz Porzsolt
Background: Sir Archibald Cochrane and Sir Austin Bradford Hill requested 80 years ago answers to three questions (Can it work? Does it work? Is it worth it?) before a new intervention is implemented in day-to-day healthc...
Scopoletin a potential phytochemical therapy for antitubercular treatment drug induced liver injury (ATT-DILI) model in Wistar rats [0.03%]
scopoletin对预防和治疗抗结核药物致Wistar大鼠肝损伤的研究
Swati Sharma,Vishal Sharma,Sunil Taneja et al.
Swati Sharma et al.
Objectives: The hepatoprotective properties of scopoletin have been explored in carbon tetrachloride (CCl4) induced liver injury but not in drug-induced liver injury (DILI) scenarios. Only N-acetyl-cysteine (NAC) has prov...
A solid lipid particle formulation of long pepper extract reduces pain and astrocyte activation in a rat model of neuropathic pain [0.03%]
一种长胡椒提取物固体脂质颗粒配方可减少神经病理性疼痛大鼠模型中的疼痛和星形胶质细胞活化
Sri-Arun Iamjan,Siriluk Veerasakul,Samur Thanoi et al.
Sri-Arun Iamjan et al.
Objectives: To investigate the effects of solid lipid microparticle (SLM) creams containing a long pepper extract (LPE) or piperine on neuropathy-related pain and the expression of glial fibrillary acidic protein (GFAP) a...
Potential anti-cancer activity of Moringa oleifera derived bio-active compounds targeting hypoxia-inducible factor-1 alpha in breast cancer [0.03%]
辣木提取活性成分通过靶向乳腺癌缺氧诱导因子-1 alpha发挥潜在的抗肿瘤作用
Neha Masarkar,Suman Kumar Ray,Zirha Saleem et al.
Neha Masarkar et al.
Breast cancer (BC) will become a highly detected malignancy in females worldwide in 2023, with over 2 million new cases. Studies have established the role of hypoxia-inducible factor-1α (HIF1α), a transcription factor that controls cellul...
Optimization of total phenolic content, total flavonoid content and anti-gout properties of polyherbal formulation [0.03%]
聚 Herbal制备中总多酚含量、总黄酮含量和抗痛风性能的优化
Lim Sin Yee,Mohd Fadzelly Abu Bakar,Norazlin Abdullah et al.
Lim Sin Yee et al.
Objectives: An increase in gout prevalence has drawn attention among society and this situation drives the exploration of more favourable treatment using traditional medicinal plants which are rich in phenolic and flavono...
Non-monotonic dose-response of di-(2-ethylhexyl) phthalate isolated from Penicillium citrinum XT6 on adipogenesis and expression of PPARγ and GLUT4 in 3T3-L1 adipocytes [0.03%]
源自青霉菌的邻苯二甲酸二丁酯对3t3-l1脂肪细胞增殖和pparγ及glut4表达的影响剂量效应非单调性研究
Fitra Fauziah,Hirowati Ali,Cimi Ilmiawati et al.
Fitra Fauziah et al.
Objectives: Adipogenesis is the fat cell formation process regulated by peroxisome proliferator-activated receptors (PPARγ). The insulin-responsive glucose transporter 4 (GLUT4) has a major role in glucose uptake and met...
Alterations in expression of α1-adrenergic receptors possibly are involved in prevention of age-associated apoptosis in rat hippocampus by treadmill exercise [0.03%]
α1肾上腺素受体在跑步机运动改善大鼠海马衰老相关凋亡中的可能作用机制研究
Leila Chodari,Maedeh Ghasemi,Nasrin Mehranfard
Leila Chodari
Objectives: Exercise is assumed to attenuate age-related neuronal apoptosis, but the detailed mechanism(s) is not fully understood. α1-Adrenergic receptors (ARs) can either trigger or suppress apoptosis, therefore, here ...
Modulation of glucose metabolism-related genes in diabetic rats treated with herbal synthetic anti-diabetic compound (α-HSA): insights from transcriptomic profiling [0.03%]
基于转录组学分析的化药复方（α- HSA）治疗糖代谢相关基因调控研究
Nikhil Khurana,Suman Bala Sharma
Nikhil Khurana
Objectives: Eugenia jambolana is a medicinal plant traditionally used for treating diabetes. The bioactive compound FIIc, which is derived from the fruit pulp of E. jambolana, has been identified and purified as α-HSA. P...