Evaluation of betanin as a multi-target therapeutic agent against diabetic kidney disease, peripheral neuropathy, and dyslipidaemia in a rodent model of type 2 diabetes [0.03%]
评估甜菜碱作为2型糖尿病动物模型糖尿病肾病、外周神经病变和脂质异常多靶点治疗药物的效果
Rathi Bishakha Jayprakash,Amrita Parida,Ramya Kateel et al.
Rathi Bishakha Jayprakash et al.
Objectives: Diabetes mellitus leads to many complications in long term. This study aims to assess the effect of betanin on complications like diabetic kidney disease (DKD), diabetic peripheral neuropathy (DPN) and dyslipi...
Omega-3 rich Rastrelliger kanagurta fish oil attenuates IL-6 and MMP-9 expression and preserves joint integrity in rheumatoid arthritis-induced rats [0.03%]
富含ω-3的鼠线鱼鱼油可减轻类风湿关节炎诱导的大鼠的白细胞介素-6和基质金属蛋白酶-9表达并保持其关节完整性
Muhammad Ali,Tetri Widiyani,Elisa Herawati
Muhammad Ali
Objectives: Omega-3 polyunsaturated fatty acids are known for their anti-inflammatory potential in autoimmune disorders. This study aimed to investigate the effects of Rastrelliger kanagurta fish oil on pro-inflammatory c...
Black Maitake mushroom (Grifola frondosa) extract exerts anti-cancer effects and enhances the efficacy of chemotherapeutic drugs in 2D and 3D models of triple-negative breast cancer [0.03%]
黑毛木耳（葛粉团）提取物对三阴性乳腺癌二维和三维模型的抗癌作用及增强化疗药物疗效的作用
Silvia DeMarco,Sona Regonda,Siyaram Pandey
Silvia DeMarco
Intoduction: Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype that lacks hormone receptors and HER2 amplification, limiting targeted therapy options. Chemotherapeutics like cisplatin and taxol a...
Serum TNF-α, oxidized LDL, and APOCII as novel predictors for familial mediterranean fever in Egyptian children: a cross-sectional study [0.03%]
埃及儿童家族地中海热的新血清生物标志物：一项横断面研究
Hala T El-Bassyouni,Khaled Hamed,Eman Refaat Youness et al.
Hala T El-Bassyouni et al.
Intoduction: Persistent subclinical inflammation is a hallmark of familial Mediterranean fever (FMF), the most common autoinflammatory disease. Among the key mediators implicated in this chronic inflammatory state are tum...
The effect of beetroot (Beta vulgaris L.) ethanolic extract in the nephrolithiasis rat model [0.03%]
甜菜(Beta vulgaris L。)乙醇提取物对肾结石大鼠模型的影响
Fitri Rachmaini,Dwisari Dillasamola Isberd,Winda Adzka Fitri et al.
Fitri Rachmaini et al.
Objectives: Nephrolithiasis is a prevalent urinary condition that often leads to the development of secondary stones. The biological activity of red beetroot (Beta vulgaris rubra) and its potential as a disease-prevention...
Effects of combined nutritional supplementation with biotin, omega-3 polyunsaturated fatty acids and vitamin D in depression: a preclinical study [0.03%]
生物素、欧米茄-3多不饱和脂肪酸和维生素D联合营养补充剂对抑郁症的疗效：一项临床前期研究
Harsha Gautam,Amrita Parida,Shreya Hegde et al.
Harsha Gautam et al.
Objectives: To evaluate the antidepressant-like effects of combined nutritional supplementation with omega-3 fatty acids, vitamin D, and biotin, alone and in combination with half-dose fluoxetine, in a Chronic Unpredictab...
Peruvoside, a cardiac glycoside, induces cell cycle arrest in non-small cell lung cancer (A549 cell line) and modulates PI3K/AKT/mTOR [0.03%]
peruvoside诱导非小细胞肺癌(A549细胞系)细胞周期阻滞及调节PI3K/AKT/mTOR信号通路
Zahraa Shehab Ahmed,Meroj Ahmed Jasem,Bahir Abdul-Razzaq Mshimesh et al.
Zahraa Shehab Ahmed et al.
Objectives: Lung cancer constitutes a global health crisis that leads to mortality. The cellular signaling and cell cycle are disrupted in lung cancer. From time immemorial, plants have been a major source of medications....
Evaluating the anticancer activity of black maitake odaira extract-prothera (Grifola frondosa) and its interactions with common chemotherapeutics in in-vitro and in-vivo models of human colorectal cancers [0.03%]
评估黑舞茸odaira提取物-Prothera（玉灵菇）及其与常见化学疗法在人类结直肠癌体外和体内模型中的抗肿瘤活性及相互作用
Hannah Drew,Vanessa Chimienti,Sona Regonda et al.
Hannah Drew et al.
Objectives: Black maitake odaira extract-prothera (Grifola frondosa; BME), a β-glucan-rich natural product, has demonstrated anticancer activities including immunomodulation, inhibition of metastasis, enhanced chemothera...
Decoding the neuroprotective secrets of Tinospora sinensis: navigating the rotenone induced storm of behavioral and biochemical challenges in Parkinson's disease rat models [0.03%]
解读蛇葡萄的神经保护秘密：在帕金森病大鼠模型中导航罗特诺因诱导的行为和生化挑战风暴
Prabha Bhong,Suvarna Ingale,Pallavi Jadhav
Prabha Bhong
Objectives: Parkinson's disease (PD) is a chronic neurodegenerative disorder that leads to motor and non-motor challenges, significantly impacting the quality of life. Research highlights body's antioxidant systems role i...
Impact of monk fruit sweetener on liver architecture, oxidative stress, and enzyme markers in adult Wistar rats [0.03%]
罗汉果甜苷对成年wistar大鼠肝结构、氧化应激及酶标志物的影响
Ibrahim Yusuf,Sirajo M Umar,Rabiu I Fage
Ibrahim Yusuf
Background: Non-nutritive sweeteners (NNS) such as monk fruit sweetener (MFS) are increasingly adopted as sugar alternatives due to their high sweetening potency and low caloric content. Despite their widespread use, the ...