Mats Voogelaar,Milly S Tedja,Jeremy A Guggenheim et al.
Mats Voogelaar et al.
Purpose: The genetic landscape of myopia has advanced considerably since the previous International Myopia Institute genetics reports. This white paper provides an updated overview of current findings on myopia genetics a...
Monosomy 3 Prediction by Clinical Features and BAP1 Staining and Its Value When Integrated in Liverpool Uveal Melanoma Prognosticator Online (LUMPO3) [0.03%]
临床特征和BAP1染色预测3号单体及整合至利物浦脉络膜黑色素瘤在线预后模型（LUMPO3）中的价值
Hung-Da Chou,Antonio Eleuteri,Helen Kalirai et al.
Hung-Da Chou et al.
Purpose: To predict monosomy 3 (M3) in uveal melanoma with clinical and histopathological features, including nuclear BRCA1-associated protein 1 immunohistochemistry (nBAP1-IHC), and to evaluate its prognostication perfor...
Xi Wang,Tong Liu,Changwu Tan et al.
Xi Wang et al.
Purpose: Neural sensory systems continuously tailor themselves to adapt to changes in the surrounding environment. In motion adaptation, a certain period of exposure to consistent motion in one direction (inducer) will al...
Mapping Macrophage Diversity in Coats' Disease: A Lipid-Associated Subset in the Pathogenesis of Exudative Retinopathy [0.03%]
Coats病巨噬细胞多样性的地图绘制：与脂质相关亚群在渗出性视网膜病变发病机制中的作用
Runmin Xie,Tianyu Mao,Na Su et al.
Runmin Xie et al.
Purpose: Coats' disease is a retinal vasculopathy characterized by retinal telangiectasia, exudation, and retinal detachment. Lipid exudates serve as crucial biomarkers for the assessment and prediction of disease progres...
Studies on Hydrostatic Pressure Responses to Piezo1 and TRPV4 in the Mouse Lens [0.03%]
关于小鼠晶状体Piezo1和TRPV4对静水压反应的研究
Junyuan Gao,Richard T Mathias,Kulandaiappan Varadaraj et al.
Junyuan Gao et al.
Purpose: The lens has a feedback control system made by transient receptor potential vanilloid 4 (TRPV4) and TRPV1 to sense pressure and activate ion transport to maintain intracellular hydrostatic pressure close to zero ...
Optic Disc Characteristics in Children Born Preterm With and Without ROP: Results From the Gutenberg Prematurity Eye Study Young (GPESY) [0.03%]
早产儿视网膜病变对儿童视盘特征的影响：古腾堡早产儿眼病研究（GPESY）项目结果报告
Achim Fieß,Sandra Gißler,Stephanie Grabitz et al.
Achim Fieß et al.
Purpose: We investigated optic nerve head morphology in children born preterm with and without retinopathy of prematurity (ROP), focusing on peripapillary retinal nerve fiber layer (pRNFL) thickness, minimal rim width (MR...
Observational Study
Investigative ophthalmology & visual science. 2025 Oct 1;66(13):21. DOI:10.1167/iovs.66.13.21 2025
Comparative Transcriptomic Profiling of Corneal Compartments Using Single-Cell and Single-Nucleus Sequencing [0.03%]
基于单细胞和单核转录组测序的角膜各层组织比较基因表达图谱
Hongran Zhao,Xiaoyu Li,Xiaowen Zhang et al.
Hongran Zhao et al.
Purpose: Single-cell RNA sequencing (scRNA-seq) and single-nucleus RNA-sequencing (snRNA-seq) offer complementary advantages for corneal transcriptomics study. However, variations in cell-type distribution across platform...
Hidden Splicing Variants in Inherited Retinal Degeneration: Discovery and Functional Insight [0.03%]
遗传性视网膜变性中隐藏的剪接变异体：发现与功能见解
Yu-Shu Huang,Wen-Ting Lu,I-Hsuan Chiu et al.
Yu-Shu Huang et al.
Purpose: To enhance the molecular diagnosis of inherited retinal degeneration (IRD) by systematically identifying pathogenic splicing variants and characterizing their transcript-level consequences. ...
Alterations of Photoreceptor Synaptic Ribbons in the Retina of a Human Patient With Oculocutaneous Albinism Type 1 (OCA1) [0.03%]
人类眼皮肤白化病Ⅰ型(OCA1)患者视网膜感光细胞突触带状体的改变
Anna Franziska Köller,Barbara Käsmann-Kellner,Fritz Benseler et al.
Anna Franziska Köller et al.
Purpose: Albino (Tyrc-2J/Tyrc-2J) C57BL/6J mice carry a mutation in the tyrosinase gene and are known to display alterations of photoreceptor synaptic ribbons. In the present study, we wanted to test whether similar alter...