Quantitative Evaluation of Geographic Atrophy Progression Using Geographic Atrophy Lesion Front Displacement [0.03%]
基于地黄斑萎缩病灶前沿移动量的地黄斑萎缩进展量化评估方法研究
Shinichiro Chujo,Jiwon Baek,Akihito Uji et al.
Shinichiro Chujo et al.
Purpose: To evaluate the temporal behavior and relative variability of a margin-based metric, lesion front displacement, for quantifying geographic atrophy (GA) progression secondary to age-related macular degeneration an...
Direct Correlation of Levels of Meibum Cholesteryl Esters, Hydrocarbon Chain Saturation, and Protein With Lipid Structure, in Relation to Age and Dry Eye [0.03%]
脂质结构与年龄及干眼相关的角结膜分泌物胆固醇酯、烃链饱和度和蛋白质水平的直接关联
Muhammed Shah Shaji,Khanom Mahbuba,Douglas Borchman et al.
Muhammed Shah Shaji et al.
Purpose: Meibum compositional, structural, and functional relationships have been inferred indirectly. The current study measured the relationships among cholesteryl esters (CEs), lipid hydrocarbon chain unsaturation (HCu...
Yuze Mi,Zhe Tao,Zhengbo Xue et al.
Yuze Mi et al.
Purpose: To characterize the shared genetic architecture underlying the frequent co-occurrence of myopia and exotropia. Methods: Levera...
Amblyopia Severity Predicts Fixation Dysfunction Independent of Nystagmus and Foveation Disruption in Fusion Maldevelopment Nystagmus [0.03%]
弱视严重程度可独立于眼球震颤和中心凹注视紊乱预测融合发育不良性眼球震颤的固视功能障碍
Hanieh Agharazi,Priya Raju,Archayeeta Rakshit et al.
Hanieh Agharazi et al.
Purpose: Fixation instability in amblyopia, with or without strabismus, reflects abnormalities in physiologic fixational eye movements (FEMs) and, in some individuals, fusion maldevelopment nystagmus (FMN), a pathognomoni...
Topical Glycolysis Inhibition Restores MAVS-Associated Antiviral Signaling in Herpes Simplex Keratitis [0.03%]
糖酵解抑制恢复疱疹性角膜炎中MAVS相关抗病毒信号转导
Wei Xu,Huiru Liu,Zihan Cheng et al.
Wei Xu et al.
Purpose: Herpes simplex keratitis (HSK) is a leading cause of infectious corneal blindness. Host antiviral responses, particularly type I interferon (IFN) signaling, are impaired during corneal herpes simplex virus type 1...
Extrinsic Modulation of the Zonular Tension Induces Calcium Influx in Lens Fiber Cells That Is Mediated by Mechanosensitive TRPV1 and TRPV4 Channels [0.03%]
囊膜张力的调控诱导晶状体上皮细胞钙离子内流并由机械敏感性TRPV1和TRPV4通道介导
Yadi Chen,Paul J Donaldson
Yadi Chen
Purpose: The purpose of this study was to determine if changing the tension applied to the rat lens via the zonules increases intracellular Ca²⁺ levels via the activation of mechanosensitive Transient Receptor Potential...
Erratum in: NAMPT Deficiency Promotes Endothelial-Mesenchymal Transition by Inhibiting Energy Metabolism and Lysosomal Acidification in Late-Onset Fuchs Endothelial Corneal Dystrophy [0.03%]
NAMPT缺乏通过抑制能量代谢和迟发性Fuchs内皮角膜 dystrophy溶酶体酸化促进内皮-间质转化的错误陈述修正：论文正文中的错误及更正
Published Erratum
Investigative ophthalmology & visual science. 2026 Jul 1;67(8):56. DOI:10.1167/iovs.67.8.56 2026
A Topographical Analysis of Visual Field Improvement in a Phase 2 Randomized Trial of Nicotinamide and Pyruvate for Open-Angle Glaucoma [0.03%]
尼古丁胺和丙酮酸治疗开角型青光眼的II期随机临床试验视野改善的地形学分析
C Gustavo De Moraes,Aakriti G Shukla,George A Cioffi et al.
C Gustavo De Moraes et al.
Purpose: The purpose of this study was to characterize topographical visual field (VF) improvement using pointwise total deviation (TD) slopes referenced to baseline severity, and to evaluate structure-function and cognit...
Association of Antibiotic Use and New-Onset ICD Coding of Geographic Atrophy [0.03%]
抗生素使用与新发地理萎缩国际分类编码关联性研究
Sean R Smith,Max J Hyman,John T Moir et al.
Sean R Smith et al.
Purpose: To determine whether exposure to antibiotics is associated with new-onset International Classification of Diseases (ICD) coding of geographic atrophy (GA). ...