Public Health [0.03%]
公共卫生
Che-Sheng Chu Sr,Chih-Sung Liang Sr,Mu-Hong Chen Sr
Che-Sheng Chu Sr
Background: The use of antidepressants in elderly patients with major depressive disorder (MDD) was associated with elevated risk of dementia, but the results published are conflicting. ...
Public Health [0.03%]
公共卫生学杂志
Yi-Chun Lin,Jen-Hau Chen,Jeng-Min Chiou et al.
Yi-Chun Lin et al.
Background: Kidney function has been shown to predict cognitive impairment in previous studies. However, limited longitudinal studies have investigated the association between kidney function and cognitive impairment. Thi...
Diego E Garcia Chialva,Diego Cifarelli,Luciana Isaja et al.
Diego E Garcia Chialva et al.
Background: Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of dementia worldwide. It is characterized by progressive neuronal degeneration and the accumulation of beta-amyloid plaques (Aβ)...
Kiran Girdhar
Kiran Girdhar
Background: Understanding the molecular mechanisms of human brain development, maintenance, and age-related decline is crucial for interpreting the genetic architecture of developmental and late age related neurodegenerat...
Altan Rentsendorj,Dieu-Trang Fuchs,Jean-Philippe Vit et al.
Altan Rentsendorj et al.
Background: Alzheimer's disease (AD) pathology extends beyond the brain to the neurosensory retina. Ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1), a key enzyme in the ubiquitin-proteasome system, has a synaptic protec...
Antonios Dougalis,Polina Abushik,Anssi Pelkonen et al.
Antonios Dougalis et al.
Background: The molecular mechanisms leading to Alzheimer's disease (AD) are poorly known. This is due to the lack of human tissue samples for research representing early changes of AD pathology, raising a need for develo...
Public Health [0.03%]
公共卫生
Florilyn Joyce Chulsi Bentrez
Florilyn Joyce Chulsi Bentrez
Background: The increasing prevalence of dementia among the elderly population poses a significant public health challenge, particularly in urban areas like Baguio City, Philippines. With a growing number of individuals l...
Public Health [0.03%]
公共卫生
Jessica G Amos,Lidan Zheng,Sophie Andrews et al.
Jessica G Amos et al.
Background: Modifiable lifestyle factors offer potential to reduce dementia risk, underscoring the need to identify effective behaviour change techniques (BCTs), particularly as the format of interventions change to incor...
Public Health [0.03%]
公共卫生
Rongxiang Tang,Jeremy A Elman,Jack F V Hunt et al.
Rongxiang Tang et al.
Background: Neighborhood disadvantage captures the socioeconomic context of an individual's environment and is associated with poorer cognition and increased vulnerability to MCI and AD independently of individual-level s...
Danyeong Kim,Da-Eun Jeong,Yunseo Gong et al.
Danyeong Kim et al.
Background: ATP10B encoded a phospholipid flippase, essential for maintaining cellular homeostasis, which was implicated in the pathogenesis of Parkinson's disease (PD). Previous studies suggested an association between A...