Efficacy of a language-concordant community health worker intervention to improve community-to-clinic linkage for dementia care: results of the randomized trial PLAN [0.03%]
一种语言一致的社区保健工作者干预改善痴呆护理的社区到诊所联系的有效性：PLAN随机试验结果
Hae-Ra Han,Nancy Perrin,Ji-Young Yun et al.
Hae-Ra Han et al.
Background: Linkage to medical services enables timely diagnosis and treatment, yet racial/ethnic minority older adults with limited English proficiency (LEP) face substantial barriers. We tested Preparing Healthy Aging t...
Randomized Controlled Trial
Alzheimer's & dementia : the journal of the Alzheimer's Association. 2026 Jun;22(6):e71541. DOI:10.1002/alz.71541 2026
Outcome-specific risk factors challenge universal dementia prevention priorities: Findings from the Egyptian Dementia Network Registry [0.03%]
针对特定风险因素的痴呆症预防优先事项：埃及痴呆网络注册表的结果挑战了普遍性观点
Shimaa A Heikal,Eman M Khedr,Gharib Fawi et al.
Shimaa A Heikal et al.
Background: Dementia prevention targets modifiable factors from high-income cohorts, but most studies conflate dementia status and cognitive performance, distinct outcomes with potentially different outcomes. This distinc...
Stephanie G Eberly,Chayarndorn Phumsatitpong,Catherine E Munro et al.
Stephanie G Eberly et al.
Stress is increasingly recognized as an important, modifiable factor for Alzheimer's disease (AD), yet its roles in initiation, progression, and outcomes remain incompletely elucidated. Epidemiologic studies link chronic stress, early-life ...
Validity of the two different scoring methods of the Clinical Dementia Rating scale in staging and detection of cognitive impairment in the Peruvian population [0.03%]
临床痴呆评定量表的两种不同评分方法在秘鲁人群认知障碍分期和检出中的有效性
Junior Senador,Rosa Montesinos,Belén Custodio et al.
Junior Senador et al.
Introduction: In Peru, the Global Deterioration Scale is the only available tool for assessing dementia severity. The Spanish translation and cultural adaptation of the Clinical Dementia Rating (CDR) is used locally but r...
Association of imaging-defined brain age with disease severity and adverse outcomes in CADASIL [0.03%]
CADASIL中基于影像学定义的脑年龄与疾病严重程度和不良预后的关系
Shao-Lun Hsu,Pei-Lin Lee,Kun-Hsien Chou et al.
Shao-Lun Hsu et al.
Introduction: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by cysteine-altering NOTCH3 variants. We examined whether neuroimaging-defined brain age is alte...
The landscape of dementia in India: Prevalence, risk factors, and opportunities ahead [0.03%]
印度的痴呆症现状：患病率、风险因素及未来机遇
Akankshi Oberoi,Karen Cai,Rebecca West et al.
Akankshi Oberoi et al.
India's rapidly aging population faces a dementia burden, yet data on factors affecting dementia risk remain limited. A narrative review of studies on dementia prevalence and risk factors in India was conducted using Medline, Scopus, and Go...
Ex vivo comparison of ACU193 and lecanemab reveals binding differences in mouse brain [0.03%]
体外对比分析ACU193和lecanemab在小鼠脑组织切片上的结合差异
Martine B Grenon,Erika N Cline,Jasna Jerecic et al.
Martine B Grenon et al.
Introduction: Immunotherapy targeting amyloid beta (Aβ) is limited by amyloid-related imaging abnormalities (ARIA), hypothesized to result from the direct binding of anti-Aβ monoclonal antibodies (mAbs) to vascular cere...
Factors linked to informal caregiver burden in dementia across Latin America and the Caribbean: A systematic review and meta-analysis [0.03%]
拉丁美洲和加勒比海地区痴呆症非正式照料负担的相关因素：系统评价和meta分析
Paula Quintero-Cardona,María Alejandra Tangarife,John Blandon et al.
Paula Quintero-Cardona et al.
Informal caregivers are central to dementia care in Latin America and the Caribbean (LAC), yet determinants of caregiver burden remain insufficiently characterized. We conducted a systematic review and meta-analysis of studies examining pat...
Influence of an AQP4 haplotype and sleep duration on early Alzheimer's disease [0.03%]
AQP4基因单体型及睡眠时长对早期阿尔茨海默病的影响
Emma L Palatsides,Stephanie Yiallourou,Dibya Himali et al.
Emma L Palatsides et al.
Introduction: Aquaporin-4 (AQP4) is thought to facilitate Alzheimer's disease (AD) protein clearance during sleep. We examined whether AQP4 genetic variation was associated with AD pathology or modified the association be...