Liposomes: An Intelligent Drug Delivery System for Translational Applications in Bone Biomedicine [0.03%]
脂质体在骨组织生物医学转化应用中的智能药物传输系统研究
Weike Feng,Yun Xue,Bin Chang et al.
Weike Feng et al.
The treatment of complex orthopedic diseases such as osteomyelitis, rheumatoid arthritis, and osteosarcoma is often hindered by the limitations of systemic drug administration, including poor bioavailability, severe side effects, and an ina...
Biomechanical Assessment of Femur Fracture Fixation Using Modified Locking Compression Plate Made of Biodegradable and Non-Biodegradable Materials Under Physiological Loading During Healing Phases [0.03%]
基于可降解与不可降解材料的改良锁定压缩板股骨骨折内固定的生物力学分析
Girish Chandra,Rajdeep Ghosh,Vivek Verma
Girish Chandra
Transverse femoral fractures heal through a complex secondary healing process, often stabilized using locking compression plates (LCPs) that maintain compression across an interfragmentary gap. Conventional LCPs made of non-biodegradable Ti...
Understanding the Influence of Modified Surfaces on Early Dynamics of Osseointegration by Histomorphometric Analysis: An In Vivo Study [0.03%]
基于活体实验的组织计量学分析理解改性表面层对骨结合早期动态的影响机制的研究
Hanna Aludden,Ana Flávia P Santos,Christer Dahlin et al.
Hanna Aludden et al.
Rapid osseointegration remains a topic of interest in implant dentistry; however, the effects of modified surfaces during the early stages of osseointegration are not entirely elucidated. With that purpose, this study aimed to critically in...
Functional Hybrid Chitosan Coatings With Cu Nanoparticles on the Shape Memory NiTi Enabling Bactericidal Activity [0.03%]
具有铜纳米颗粒的壳聚糖杂化功能涂层在镍钛形状记忆上启用杀菌活性
Piotr Jabłoński,Agnieszka Kyzioł,Halina Krawiec et al.
Piotr Jabłoński et al.
In this study, we introduce a hybrid approach for fabricating multifunctional coatings composed of chitosan and copper nanoparticles (CuNPs) on NiTi substrates. The fabrication process combines the immersion technique for chitosan layer dep...
Allen Zennifer,Sai Sadhananth Srinivasan,Suranji Wijekoon et al.
Allen Zennifer et al.
Large-area bone loss from disease, trauma, or congenital defects requires surgical procedures and bone grafting. Alveolar bone loss from severe periodontal disease and non-unions often demands immediate grafting. Treating large alveolar bon...
Evaluation of Cell Migration Through Electrospun PCL Fiber Mats With Controlled Thickness [0.03%]
控制厚度的PLC纤维基质的细胞迁移评估研究
Yosuke Uemura,Hiroyuki Tonami
Yosuke Uemura
Electrospun fiber mats are widely studied as scaffolds, yet cell migration in the thickness (z) direction remains poorly understood. In this study, poly(ε-caprolactone) (PCL) mats with reproducibly controlled thicknesses were prepared by c...
Lung Biopsy Tract Sealant and Fiducial Marker Based on a Hydrogel/Shape Memory Polymer Foam Composite With Multimodal Contrast [0.03%]
基于水凝胶/形状记忆聚合物泡沫复合材料的多模态对比肺穿刺通道封闭剂和定位标记物
Matthew A Jungmann,Donald Bowen,Ethan VanDever et al.
Matthew A Jungmann et al.
Lung tissue biopsies can result in a collapsed lung in the patient via leakage of air (pneumothorax) from an open biopsy tract. To reduce the risk of pneumothorax, clinicians will implant a sealant to prevent leakage of air from the tract. ...
Targeting the Pathological Microenvironment in Diabetic Foot Ulcers: Advances in Drug Delivery Systems for Improved Healing [0.03%]
糖尿病足溃疡病理微环境的靶向治疗：促进伤口愈合的药物递送系统新进展
Wanqing Dai,Zhengguang Li,Rucheng Zheng et al.
Wanqing Dai et al.
Diabetic foot ulcers (DFUs) are among the most severe and disabling complications of diabetes, characterized by delayed healing, frequent recurrence, and a high risk of infection and amputation. Their pathogenesis is sustained by a hostile ...
Preparation of GelMA Microspheres Loaded With Silver Ions and Curcumin for Antibacterial and Antioxidant Functions in Diabetic Chronic Wounds [0.03%]
用于糖尿病慢性伤口的抗菌和抗氧化功能的载银离子及姜黄素明胶美得尔微球的制备
Zhengnan Zhao,Yingming Li,Yongwei Yin et al.
Zhengnan Zhao et al.
Diabetic chronic wounds are difficult to heal due to persistent inflammation, excessive oxidative stress, and high infection risk. Herein, a multifunctional GelMA-based microsphere co-loaded with silver ions and curcumin (GelMA-MS@Ag/Cur) w...