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Optimized Protocol for the Isolation of UHMWPE Wear Debris by Lyophilization and Chemometric Identification (EDS/PCA)

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Aseptic osteolysis induced by ultra-high-molecular-weight polyethylene (UHMWPE) wear debris has historically been a major cause of late failure in total hip arthroplasty, highlighting the need for more robust methods to isolate and identify wear particles in c... ...