Effect of Nanotextured Stainless Steel Surface Features on Antibacterial Properties and Osteoblast Activity In Vitro [0.03%]
纳米纹理不锈钢表面特征对 antibacterial 性能和体外成骨细胞活性的影响
Anuja Tripathi,Julie A Champion
Anuja Tripathi
Bacterial colonization and poor osteointegration are significant challenges for stainless steel implants. These issues often lead to implant-associated infections, localized tissue damage, and implant failure, which can result in chronic in...
Material Compatibility of Poly(Ether)urethane 80A With Vaporized Hydrogen Peroxide Sterilization: A Comprehensive Evaluation of Oxidative Stability and Biocompatibility [0.03%]
医用聚醚尿烷80A与气态过氧化氢灭菌的相容性：系统评价其氧化稳定性和生物相容性
Kimberly A Chaffin,Eric K Long,Angela L Hendrickx et al.
Kimberly A Chaffin et al.
Poly(ether)urethanes (PEUs) are widely used in long term implanted medical devices. Their susceptibility to oxidative degradation has raised concerns regarding compatibility with vaporized hydrogen peroxide (VH2O2) sterilization. This study...
Osteoblastic Responses of Sandblasted TA6V Femoral Implants Functionalized With Phosphonate Polymers via UV-Induced Direct Grafting [0.03%]
通过UV光直接接枝膦酸聚合物功能化沙粒喷射Ta6v股骨植入物的成骨细胞响应研究
Luis Lechaptois,Caroline Pereira,Sophie Le Cann et al.
Luis Lechaptois et al.
Most of the orthopedic implants are nowadays manufactured using titanium or titanium alloy materials due to their mechanical properties and good compatibility with human tissues. Still, implant rejections frequently occur and are related to...
Mechanism of Bone Marrow Mesenchymal Stem Cells-Derived Extracellular Matrix for Articular Cartilage Repair [0.03%]
骨髓间充质干细胞来源的细胞外基质促进软骨修复的作用机制研究
Nian Sun,Ze Zhang,Long Li et al.
Nian Sun et al.
Articular cartilage injuries present a significant clinical challenge due to the tissue's limited self-repair capacity and the inadequacy of current regenerative strategies. This study aimed to investigate whether bone marrow mesenchymal st...
Anti-Biofilm Properties of Polyurethane Biomaterials Tethered With Small Molecules via Polyethylene Glycol Linker [0.03%]
通过聚乙二醇连接器固定小分子的聚氨酯生物材料的抗菌膜性能
Jiale Liu,Chen Chen,Jennifer L Booth et al.
Jiale Liu et al.
Biofilm-associated microbial infection is one of the main complications for long-term use of biomaterials in implantable medical devices. Bacterial intracellular nucleotide second messenger signaling is widely recognized to be involved in b...
Cobalt-Doped Biphasic Calcium Phosphate Orchestrates Osteogenesis-Angiogenesis Signals via Hypoxia-Mimetic Signaling [0.03%]
类库珀仿生磷酸钙通过模拟缺氧信号协调骨诱导-血管发生信号
Luísa Camilo Suter,Gerson Santos de Almeida,Matheus Luquirini Penteado Dos Santos et al.
Luísa Camilo Suter et al.
We engineered a cobalt-doped biphasic calcium phosphate (CoBCP) by combining monetite-derived pyrophosphate and β-tricalcium phosphate (β-TCP) with lattice-incorporated Co2+, and evaluated its physicochemical profile and in vitro bioactiv...
Tiger Tongue-Inspired Bionic Microneedle Patch With Dual Mechanical-Pharmacological Functions for Enhanced Wound Healing [0.03%]
一种受虎舌启发的集成了力学和药物学功能的微针贴片促进伤口愈合
Yangguang Niu,Jingyuan Ren,Kangxun Zhao et al.
Yangguang Niu et al.
Effective skin wound healing requires reliable fixation and infection prevention. Inspired by the inclined papillary structure of the tiger's tongue, we developed a biomimetic microneedle patch that integrates mechanical stability with anti...
Self-Assembling Hydrogel for Controlled Release of bFGF and Ang-1 Mimetic Peptide Promotes Neurovascular Repair in Ischemic Stroke Rats [0.03%]
一种可自组装水凝胶同时控制递送bFGF和Ang-1模拟肽促进缺血性脑卒大鼠神经血管修复
Ange Nie,Weihong Nie,Na Zhou et al.
Ange Nie et al.
Self-assembling peptide hydrogels represent a promising strategy for growth factor delivery and tissue repair, with the advantage of sustained release and micro-environment response characteristics. In the present study, a multiple biofunct...
Safety, Distribution, and Pharmacokinetics of Biodegradable P(AAm-co-MAA) Nanogels Following Systemic Administration in Mice [0.03%]
口服P(AAm-co-Maa)纳米凝胶在小鼠体内的安全性、分布和药代动力学研究
Rana Ajeeb,Harsh Joshi,Mojtaba Ghanbari Mehrabani et al.
Rana Ajeeb et al.
Systematic analysis of the fate of hydrogel nanoparticles after in vivo administration is essential for their clinical translation. Biodegradable, disulfide-crosslinked synthetic nanogels are a promising platform for the delivery of therape...
Samyuktha S Kolluru,Abir Hamdaoui,Annabella M Mascot et al.
Samyuktha S Kolluru et al.
The vagina is a fibromuscular tube-shaped organ that plays critical roles in menstruation, pregnancy, and female sexual health. Vaginal tissue constituents, including cells and extracellular matrix components, contribute to tissue structure...