Enhancing Bone Regeneration: The Role of Biomimetic Silicified Collagen Scaffold in Osteogenesis and Angiogenesis [0.03%]
促进骨再生:仿生硅化胶原支架在成骨和血管生成中的作用
Ming-Yuan Liu,Yu-Xuan Ma,Lei Chen et al.
Ming-Yuan Liu et al.
The identification of materials that effectively promote mineralization and vascularization is crucial for advancing clinical applications in bone regeneration. Biomimetic silicified collagen scaffold (SCS) has emerged as a promising candid...
Exponentially Decreasing Antigen Release Reduces Inflammatory Markers in an Antigen-Specific Manner [0.03%]
指数递减的抗原释放以抗原特异性的方式降低炎症标志物水平
Arezoo Esrafili,Aleksandr Talitckii,Joshua Kupfer et al.
Arezoo Esrafili et al.
Vaccine development requires innovative approaches to improve immune responses while reducing the number of immunizations. In this study, we explore the impact of controlled antigen release on immune activation and regulation using programm...
Biodegradable, Antibacterial TCP Implant Coatings With Magnesium Phosphate-Based Supraparticles [0.03%]
基于镁磷材料的超颗粒可降解抗菌TCP种植体涂层
Maria Carolina Lanzino,Anika Höppel,Long-Quan R V Le et al.
Maria Carolina Lanzino et al.
This work highlights the potential of porous, bioactive coatings to advance implant technology and address critical clinical challenges. A key issue in implant coatings is to achieve the balance between infection prevention and successful o...
A Design of Experiment to Evaluate the Printability for Bioprinting by Using Deep Learning Image Similarity [0.03%]
基于深度学习图像相似性的生物打印可打印性评估设计实验研究
Leon Balters,Stephan Reichl
Leon Balters
Bioprinting is a growing area in the field of tissue engineering that offers a potential solution to the global shortage of organ transplants. Ensuring high printability is crucial for bioprinting. To better understand printability, a desig...
Development and Evaluation of an Innovative S-Flurbiprofen-Diethylamine Emulgel With Superior Transdermal Delivery and Analgesic Activity [0.03%]
一种创新的S-氟比洛芬-二乙胺乳胶凝胶的开发与评价:具有优越经皮递送和镇痛活性
Jian Zhang,Jinmeng Han,Anqi Zhu et al.
Jian Zhang et al.
This study aimed to develop an innovative (S-flurbiprofen)-diethylamine (SFP-DEA) emulgel formulation via incorporating SFP as the active pharmaceutical ingredient within a carbomer 940 gel matrix. SFP-DEA emulgel was synthesized by dissolv...
Effects of Additive Manufacturing and Sterilization on Poly(p-Dioxanone) for Short-Term Application in the Intestinal Environment [0.03%]
增材制造和灭菌对聚-p-二氧环己酮在肠道环境短期应用的影响
Stefanie Ficht,Lukas Schübel,Diana M Rojas-González et al.
Stefanie Ficht et al.
Additive manufacturing of patient specific implants made of biodegradable polymers is receiving increasing attention in the medical sector, including the trend towards manufacturing at the point-of-care. Despite this, the changes of the pol...
Strontium-Loaded Titanium and Systemic Teriparatide Synergistically Enhance Osteogenesis and Osseointegration in an Osteoporotic Rabbit Model [0.03%]
锶修饰钛种植体与全身性特立帕肽协同促进兔骨质疏松模型成骨和骨整合
Koichiro Shima,Takayoshi Shimizu,Seiji Yamaguchi et al.
Koichiro Shima et al.
Poor osseointegration of Titanium (Ti) implants in osteoporotic bone can lead to early construct failure in clinical settings. This study investigated whether combining Strontium (Sr) surface loading (modified alkali and heat treatment) wit...
Biological Responses and Hemocompatibility of Diamond-Like Carbon Thin Films on Different PEO Interlayers for Potential Cardiovascular Stent Applications [0.03%]
不同PEO中间层的类金刚石碳薄膜的生物相容性及血液相容性心血管支架潜在应用的细胞生物学响应研究
Nasir Shahin,Morteza Shamanian,Mahshid Kharaziha
Nasir Shahin
Plasma electrolytic oxidation (PEO) considerably affects controlling the degradation rate of magnesium-based implants to approach the healing period. However, the biological properties still require further improvement, particularly for blo...
Iridium-Bismuth-Oxide Coatings for Use in Neural Stimulating Electrodes: The Influence of Ir/Bi Ratio [0.03%]
用于神经刺激电极的铱-铋-氧化物涂层:不同摩尔比的影响
Xingge Xu,Irshad Ali,Sandra Minotti et al.
Xingge Xu et al.
Implantable neural prosthetics with stimulating electrodes are increasingly employed in medical practices to treat neural disabilities. The electrode material is expected to provide high charge storage and injection capacity (CSC/CIC) and l...
Multidimensional Applications and Challenges of Metal-Organic Frameworks (MOFs) in Biomedicine: From Drug Safety Evaluation to Drug Delivery [0.03%]
金属有机框架(MOF)在生物医学中的多维应用及挑战:从药物安全性评价到药物递送
Zhe Liu,Yuanye Gao,Wenyuan Shao et al.
Zhe Liu et al.
Metal-organic frameworks (MOFs) are porous materials composed of metal ions or clusters and organic ligands connected through coordination bonds, exhibiting high specific surface areas, tunable pore structures, and excellent chemical stabil...