Hemoglobin Nanofibrils as Electrospun Cell Scaffolds to Enhance Primary Satellite Cell Proliferation and Differentiation for Muscle Regeneration [0.03%]
肌再生的一级卫星细胞增殖和分化的血红蛋白纳米原纤维静电纺丝细胞支架增强作用
Qun Chen,Jin Kyo Oh,Vaughan Feisst et al.
Qun Chen et al.
Stem cells are usually sensitive to extracellular matrix (ECM), and an effective synthetic ECM to mimic there in vivo growth surroundings is always desired. Poly(ɛ-caprolactone) (PCL) is a common synthetic material extensively employed for...
Era Jain,Paul Nana Kwame Sagoe
Era Jain
Osteoarthritis (OA) is a highly prevalent, disabling, and painful disease of the joints, characterized by progressive cartilage degeneration, synovial fibrosis, and pain. Mounting evidence highlights synovial inflammation as a key driver of...
Effect of Material Properties on Neurofibromatosis Type 1 Schwann Cell Behavior [0.03%]
材料属性对NF1雪旺细胞行为的影响研究
Christine D Hampton,Sonia Nain,Ahmad Zunnu Rain et al.
Christine D Hampton et al.
Schwann cells (SC) are the principal glia in the peripheral nervous system, supporting normal peripheral nerve function, particularly in the myelination of motor and sensory axons of the peripheral nerves. In Neurofibromatosis Type 1 (NF1),...
Silk Scaffold Crypt-Villus Geometry Combined With L-WRN Feeder Cells Sustains Spatially Organized Epithelial Proliferation and Multilineage Differentiation [0.03%]
丝蛋白支架绒毛结构结合L-WRN细胞维持上皮增殖和多系分化
Sara E Rudolph,Brooke N Longo,Ying Chen et al.
Sara E Rudolph et al.
The crypt-villus axis of the small intestine provides essential structural and biochemical cues that govern epithelial renewal, barrier function, and lineage specification. However, most existing in vitro models rely on flat monolayers or v...
In Vitro Evaluation of Periodontal Fibroblast Response to Bioinspired Porous Channel-Embedded Zirconia Surfaces [0.03%]
仿生多孔通道羟基磷灰石增强氧化锆表面的牙周纤维细胞响应体外评价
Joana Ribeiro,Manuela Proença,Flávio Rodrigues et al.
Joana Ribeiro et al.
Customized implant approaches are emerging to meet specific patient needs while minimizing complications. Despite advances in osseointegrated implants, issues such as excessive bone loading, bacterial infiltration, peri-implantitis, and bon...
Biomimetic Gelatin-Based 3D Scaffolds for Enhanced Islet Microencapsulation and Functionality in Diabetes Therapy [0.03%]
用于糖尿病治疗的仿生明胶基三维支架以增强胰岛微囊化和功能
Rukhiya Salim,P S Unnikrishnan,D A Arya et al.
Rukhiya Salim et al.
Tissue-engineered scaffolds are increasingly important for improving pancreatic islet transplantation, as conventional transplantation disrupts the pancreas's native vasculature and extracellular matrix, reducing islet viability and functio...
Synthetic Mechanogenetic Gene Circuit Response in Human Induced Pluripotent Stem Cell-Derived Chondrocytes Is Altered by Matrix Stiffness [0.03%]
基质刚度改变人诱导多能干细胞来源软骨细胞合成机械遗传基因电路反应
Yu Seon Kim,Autumn Kim,Nancy Steward et al.
Yu Seon Kim et al.
Transient receptor potential vanilloid 4 (TRPV4) is a mechanosensitive ion channel found in both excitatory and non-excitatory cells in the body. In chondrocytes, TRPV4 plays a crucial role in transducing physiologic levels of mechanical lo...
Spinel-Structured MnCo2O4 Nanoclusters Mediate Multimodal and Efficient Suppression of Drug-Resistant Bacteria [0.03%]
尖晶石型MnCo₂O₄纳米簇介导多模态高效耐药细菌抑制效应
Guanlin Wu,Lizhong Wu,Yajie Zheng et al.
Guanlin Wu et al.
The global dissemination of bacterial antibiotic resistance has emerged as a formidable public health challenge. According to the World Health Organization (WHO), drug-resistant infections claim over 1.3 million lives annually, with project...
Innovations in Implant Osseointegration: Biomaterials, Surface Engineering, and Translational Strategies [0.03%]
植入物骨整合创新技术：生物材料、表面工程和转化策略
Yujin Ahn,Purva K Desai,Anna Rainey et al.
Yujin Ahn et al.
Osseointegration is critical for the long-term success of orthopedic and dental implants. This review highlights the biological mechanisms underlying bone-implant integration and recent advances in bioactive materials, drug delivery systems...
Lidocaine-TiO2 Composite Coating for Chest Tubes: Modulating Sustained Drug Release, Antiadhesive Performance, and Antibacterial Properties [0.03%]
利多卡因-二氧化钛复合涂层胸管：调节持续药物释放，防粘连性能和抗菌性能
Yutong Ding,Qianyun Zhang,Mian Xu et al.
Yutong Ding et al.
Chest tubes used in cardiothoracic surgery must meet critical clinical requirements, including effective analgesia, inhibition of protein adhesion, and prevention of infection. In this study, a dual-layered coating was developed, comprising...