Novel Antibiofilm Approach Using Bioactive Glasses F18 and 45S5 Against Clinical Isolates of Staphylococcus aureus in Chronic Rhinosinusitis [0.03%]
针对慢性鼻窦炎临床分离株的金黄色葡萄球菌的新抗菌膜方法：使用生物活性玻璃F18和45S5
João Vitor Bizinoto Caetano,Maria Clara Antunes Alves,Marina Zilio Fantucci et al.
João Vitor Bizinoto Caetano et al.
S. aureus plays a central role in chronic rhinosinusitis (CRS), contributing to acute exacerbations and persistent infections through biofilm formation. With rising antibiotic resistance, bioactive glasses such as F18 and 45S5 have emerged ...
Recombinant N-terminal Fragment of Human Vitronectin Promotes Osteoblast Adhesive Responses via αvβ3 and αvβ5 Integrins [0.03%]
人 vitronectin 重组N端片段通过αvβ3和αvβ5整联蛋白促进成骨细胞黏附反应
O Bok Kim,Sung Youn Jung,Byung-Moo Min
O Bok Kim
Vitronectin is a key extracellular matrix glycoprotein, but the functional contribution of specific residues within its N-terminal region to osteoblast activity remains poorly defined. We engineered a recombinant N-terminal fragment of huma...
Biocompatibility and Therapeutic Potential of Cinnamoyl-Diphenylalanine Dipeptide: A Double-Edged Sword [0.03%]
肉桂二苯基丙氨酸肽的生物相容性和治疗潜力：一把双刃剑
Efstratios D Sitsanidis,Visa Ruokolainen,Kari Kunnas et al.
Efstratios D Sitsanidis et al.
This study evaluates cinnamoyl-diphenylalanine dipeptide (Cin-FF), a newly introduced gelator, for its antimicrobial efficacy, biocompatibility, and potential anticancer properties in solution and gel forms. We show that Cin-FF exhibits ant...
Real Architecture for 3D Tissue (RAFT): Mechanical Properties and Ability to Support the 3D Culture of Porcine Corneal Endothelial Cells [0.03%]
用于培养猪角膜内皮细胞的三维组织真实架构（RAFT）力学特性及其三维培养能力
Meng-Chen Tsai,Alvena Kureshi,Julie T Daniels
Meng-Chen Tsai
A suitable tissue-engineered equivalent is necessary to support cultured cells for cell therapy transplantation, thereby alleviating the increasing demand for donor tissue. A compressed collagen I hydrogel, Real Architecture For 3D Tissue (...
A Cationic Block Co-Polymer for Gene Delivery in the Posterior Segment of the Eye [0.03%]
一种用于眼后段基因传递的阳离子嵌段共聚物
Amber Monteiro,Odunayo O Mugisho,Antonio de Souza et al.
Amber Monteiro et al.
Diseases of the back of the eye such as neovascular age-related macular degeneration (nAMD) are vision threatening and treatment is burdensome for patients, often requiring ocular injections every other month. Injection risks and logistics ...
Reconstruction of Tissue-Engineered Conjunctiva Using Human Amniotic Epithelial Cells and Decellularized Porcine Conjunctiva Matrix With RADA16-I Peptide Hydrogel in a Perfusion Culture System [0.03%]
Dong Yuying,Liu Jingwen,Chen Fangyuan et al.
Dong Yuying et al.
Extensive conjunctival defects present significant clinical challenges due to limitations of current treatments including donor scarcity, immune rejection, and suboptimal graft outcomes. In this study, we developed a tissue-engineered conju...
Hemoglobin Nanofibrils as Electrospun Cell Scaffolds to Enhance Primary Satellite Cell Proliferation and Differentiation for Muscle Regeneration [0.03%]
肌再生的一级卫星细胞增殖和分化的血红蛋白纳米原纤维静电纺丝细胞支架增强作用
Qun Chen,Jin Kyo Oh,Vaughan Feisst et al.
Qun Chen et al.
Stem cells are usually sensitive to extracellular matrix (ECM), and an effective synthetic ECM to mimic there in vivo growth surroundings is always desired. Poly(ɛ-caprolactone) (PCL) is a common synthetic material extensively employed for...
Era Jain,Paul Nana Kwame Sagoe
Era Jain
Osteoarthritis (OA) is a highly prevalent, disabling, and painful disease of the joints, characterized by progressive cartilage degeneration, synovial fibrosis, and pain. Mounting evidence highlights synovial inflammation as a key driver of...
Effect of Material Properties on Neurofibromatosis Type 1 Schwann Cell Behavior [0.03%]
材料属性对NF1雪旺细胞行为的影响研究
Christine D Hampton,Sonia Nain,Ahmad Zunnu Rain et al.
Christine D Hampton et al.
Schwann cells (SC) are the principal glia in the peripheral nervous system, supporting normal peripheral nerve function, particularly in the myelination of motor and sensory axons of the peripheral nerves. In Neurofibromatosis Type 1 (NF1),...
Silk Scaffold Crypt-Villus Geometry Combined With L-WRN Feeder Cells Sustains Spatially Organized Epithelial Proliferation and Multilineage Differentiation [0.03%]
丝蛋白支架绒毛结构结合L-WRN细胞维持上皮增殖和多系分化
Sara E Rudolph,Brooke N Longo,Ying Chen et al.
Sara E Rudolph et al.
The crypt-villus axis of the small intestine provides essential structural and biochemical cues that govern epithelial renewal, barrier function, and lineage specification. However, most existing in vitro models rely on flat monolayers or v...