Uniaxial Tensile Tests and Digital Image Correlation Analysis for the Mechanical Characterization of Human Fascia Lata Under Different Decellularization Treatments [0.03%]
不同脱细胞方法对人髂腰筋膜机械性能影响的单轴拉伸试验及数字图像相关分析
Francesca Demontis,Giulia Loi,Edoardo Mazzotti et al.
Francesca Demontis et al.
Fascia lata (FL) is frequently employed as a grft source in reconstructive surgery. To minimize unwanted responses from the host immune system, several decellularization treatments have been proposed. Effective treatments should aim at avoi...
Adipose-Derived Stem Cell-Loaded Fish-GelMA/CMC Hydrogel Accelerates Wound Healing via Macrophage Polarization Suppression and Promoting Angiogenesis [0.03%]
负载脂肪来源干细胞的鱼明胶甲基丙烯酸酯/羧甲基纤维素钠水凝胶通过抑制巨噬细胞极化和促进血管生成加速伤口愈合
Xue Xue,Han Xue,Rong Lu et al.
Xue Xue et al.
Extensive cutaneous injuries with impaired regenerative capacity present substantial risks to both public health and socioeconomic systems. Current skin substitutes remain inadequate in fully replicating native tissue architecture and physi...
Alexandra P Christensen,John P Fisher
Alexandra P Christensen
Acellular methods are needed to vascularize 3D-printed tissue-engineered constructs for faster clinical translation. One method is to create bioactive materials that encourage migration and network formation of a patient's own cells. This s...
Silver (I) and Silver (II) Oxide Films for Biomedical Implants: Synthesis, Stability, Ion Release, and Antibacterial Efficacy [0.03%]
用于生物医学植入物的银(I)和银(II)氧化物薄膜：合成，稳定性，离子释放及抗菌功效
Maxwell Akantibila,Hailey Maurer,Matthew Urban et al.
Maxwell Akantibila et al.
Coatings of silver compounds with higher dissolution rates than metallic silver offer a promising approach for delivering Ag+ ions to prevent medical implant device-associated infections. In this study, we investigate the synthesis and char...
Flavonoid-Enriched Solanum mauritianum Leaf Extract/PU/PCL Composite Attenuates Ang II-Induced Inflammation in Cardiomyocytes and Enhances Cell Adhesion [0.03%]
富黄酮索马素叶提取物/PU / PCL复合材料可减轻Ang II诱导的心肌细胞炎症并增强细胞粘附
Aswathy Karanath-Anilkumar,Muhammad Sadiq,Suganya Ganesan et al.
Aswathy Karanath-Anilkumar et al.
Inflammatory disorders like cardiovascular diseases remain a major global health concern, with oxidative stress and chronic inflammation playing critical roles in disease progression. This study presents a PU/PCL composite functionalized wi...
Exogenous Extracellular Matrix in an Environmentally-Mediated In Vitro Model for Cardiac Fibrosis [0.03%]
基于环境介质的体外心肌纤维化模型中的外源性细胞外基质研究
Natalie Pachter,Kristen Allen,Tracy A Hookway
Natalie Pachter
Few clinical solutions exist for cardiac fibrosis, creating the need for a tunable in vitro model to better understand fibrotic disease mechanisms and screen potential therapeutic compounds. Here, we combined cardiomyocytes, cardiac fibrobl...
Characterizing Piezoelectric-Blended Polydimethylsiloxane for Use as a Mechanoelectrical Responsive Cell Culture Substrate [0.03%]
具有压电增强作用的聚二甲基硅氧烷作为机电信号响应细胞培养基质的特点研究
Alexis P Applequist,Lance D Cordes,Laís A Ferreira et al.
Alexis P Applequist et al.
In this study, we developed a piezoelectric-polydimethylsiloxane (pz-PDMS) composite by blending poly(vinylidene fluoride-co-trifluoroethylene) (P(VDF-TrFE)) with PDMS to create a biocompatible, mechanoelectrical responsive material. The pz...
In Vitro Oxidative Degradation of Hydroxyapatite Biopolymer Nanocomposites and the Resulting Consequences on Their Mechanical Performance [0.03%]
羟基磷灰石-生物聚合物纳米复合材料的体外氧化降解及其对力学性能的影响分析
Elizabeth V Diederichs,Dibakar Mondal,Thomas L Willett
Elizabeth V Diederichs
Development of synthetic biomaterials for skeletal reconstruction has progressed rapidly, driven partly by demand to reduce dependency on allografts. One class of materials, biopolymer nanocomposites, has shown promise when combined with ad...
Georgios Mikalef,Zoe Schofield,Samuel Robert Moxon et al.
Georgios Mikalef et al.
Hydrogels that can change shape on the application of an electric field are receiving increasing attention due to their potential to fulfill a range of functions in biomedicine, including the controlled release of therapeutic agents or the ...
Dynamic Loading Does Not Interfere With the Initial Repopulation of Decellularized Tendons: An Ex Vivo Study [0.03%]
动态加载不会干扰去细胞化肌腱的初始再填充：体外研究
Janne Spierings,Florencia Abinzano,Elias Salzer et al.
Janne Spierings et al.
Rupture of the anterior cruciate ligament (ACL) is a common injury resulting in joint instability. Tendon autografts, the gold standard to reconstruct a ruptured ACL, contain dead or dying cells upon implantation that can initiate early loc...