Hyaluronic Acid-Based, Double Network Hydrogels With Tunable Viscoelasticity for Neural Cell Culture [0.03%]
用于神经细胞培养的可调粘弹性的透明质酸基双网络水凝胶
Talia Sanazzaro,Sabrina Pietrosemoli Salazar,Neha Arvinth et al.
Talia Sanazzaro et al.
Brain tissue is the softest, most viscoelastic tissue in mammals and these mechanical properties strongly influence cell phenotypes. However, conventional hydrogels for 3D cultures rarely provide the ability to tune the elasticity (G') inde...
Comparative Analysis of Matrigel and Tunable Collagen-Fibrin Blends for in Vitro Skeletal Muscle Models [0.03%]
Matrigel与可调式胶原蛋白-纤溶酶模型在体外骨骼肌模型中的比较分析
Jorge A Mojica-Santiago,Gopal Agarwal,Steven Robles-Blasini et al.
Jorge A Mojica-Santiago et al.
In this study, we describe the gelation kinetics, cytocompatibility, and mechanical properties of interpenetrating networks of collagen (COL), fibrin (FIB), hyaluronan (HA), and laminin (LAM) to evaluate their potential to produce mature sk...
A Photoinitiator-Free Bioink Platform: Tyrosine-Assisted UV Crosslinking of Decellularized Extracellular Matrix/Zein Scaffolds Optimized by Full Factorial Design [0.03%]
无需光引发剂的生物墨水平台：全因子设计优化的脱细胞基质/玉米蛋白酶支架的酪氨酸辅助紫外线交联技术
Banuay Coşkun,Özlem Biçen Ünlüer
Banuay Coşkun
The clinical translation of 3D-bioprinted tissues is significantly limited by the cytotoxicity of synthetic photoinitiators used in photopolymerizable bioinks. To address this critical challenge, we developed a novel, fully photoinitiator-f...
Injectable Butyl Glycidyl Ether-Modified Methylcellulose Thermosensitive Hydrogel for Topical Delivery of Vancomycin Hydrochloride in the Treatment of Osteomyelitis [0.03%]
用于骨髓炎治疗的载氯化万古霉素可注射型丁基缩水甘油醚改性甲基纤维素热敏水凝胶的研究
Conggang Zhi,Guoqiang Wang,Bin Zhou et al.
Conggang Zhi et al.
Osteomyelitis (OM) is caused by the entry of septic cells into bone tissue. Due to systemic antibiotic side effects and drug resistance, local administration is a strategy for treating OM. In this study, a biodegradable, injectable thermose...
Fabrication of Titanium-Based Magnetic Composite Scaffold In Vitro Evaluation of Osteogenic Performance [0.03%]
钛基磁性复合支架的制备及体外骨诱导性能评价
Jie Zhang,Zengzilu Xia,Zhuoqi Xu et al.
Jie Zhang et al.
The biological inertness of Ti scaffolds prevents the proliferation and osteogenic differentiation of marrow mesenchymal stem cells (MSCs) on pure Ti scaffolds. Medical studies have shown that magnetic fields can promote the proliferation a...
A ROS-Responsive Hydrogel Microneedle System Co-Delivering Tofacitinib and Azelaic Acid for Enhanced Targeted Therapy of Rosacea [0.03%]
一种响应ROS的水凝胶微针系统联合递送托法替尼和辛酸以增强酒渣鼻的目标疗法
Yong Yu,Xiaoxia Ding,Yibin Fan et al.
Yong Yu et al.
Rosacea is a chronic inflammatory skin condition primarily affecting the face, characterized by symptoms such as persistent redness, visible blood vessels, papules, and pustules. Current treatments, including topical agents and systemic ant...
Mechanical Cues Regulate Estrogen and Progesterone-Induced Nascent ECM Deposition by Human Endometrial Stromal Fibroblasts [0.03%]
机械线索调节人子宫内膜基质纤维细胞新生ECM的雌激素和孕酮诱导分泌
Grace K Hinds,Arina Velieva,Joshua Yu-Chung Liu et al.
Grace K Hinds et al.
The endometrium, the mucosal lining of the uterus, is a highly regenerative tissue that undergoes cyclic remodeling guided by tightly regulated levels of estrogen and progesterone. Stromal cells, including fibroblasts, are embedded within t...
Microfluidic Biomaterials for Next-Generation Biomedical Platforms: Advances in Fabrication, Functionality, and Applications [0.03%]
下一代生物医学平台的微流控生物材料：在制造、功能和应用方面的进展
Boshi Xie,Jiaqi Lin,Lijuan Cui et al.
Boshi Xie et al.
Microfluidic technology has transformed biomedicine, environmental monitoring, and chemical analysis by enabling precise fluid control at the microliter to picoliter scale. As innovations in precision medicine, organ-on-a-chip systems, and ...
From Skin to Nerve: Mapping Tissue-Specific Innovations in Gelatin-Dopamine Hydrogel Platforms [0.03%]
从皮肤到神经：凝胶状多巴胺创新制图在明胶-多巴胺水凝胶平台中的组织特异性
Andreea I Dinu,Maria-Magdalena Gherghinescu,Adriana Lungu et al.
Andreea I Dinu et al.
The biomimetic adhesive qualities, biocompatibility, and multifunctionality of biomaterials containing gelatin and dopamine have propelled them to the forefront of regenerative medicine. This review's goal involves investigating all the pub...
Effects of Micropore Size Distribution in Carbonate Apatite Honeycomb Granules on Bone Replacement [0.03%]
羟基磷灰石多孔蜂窝颗粒的微孔分布对其骨替代效果的影响研究
Koichiro Hayashi,Ryo Kishida,Kunio Ishikawa
Koichiro Hayashi
Successful bone defect repair requires understanding both the role of micropores smaller than 10 μm and that of macropores. Although the effects of micropore volume have previously been reported, the influence of micropore size distributio...