Hyaluronidase-Responsive MSN-HA Coatings for Infection-Triggered Antibiotic Delivery on Titanium Surfaces [0.03%]
一种用于钛表面感染响应型载药的透明质酸分解酶响应MSN-HA涂层抗菌体系
Merve Yolum,Sakip Önder
Merve Yolum
Implant-associated infections remain a major challenge due to biofilm formation and uncontrolled antibiotic release from conventional coatings. This study presents an enzyme-responsive nanoparticle-based coating designed to enable localized...
Silk Fibroin and Gelatin Immobilization on Poly(Caprolactone) Nonwoven Mats via Carbodiimide Coupling and Electrostatic Layer-By-Layer Deposition: Characterization and Cell Growth [0.03%]
碳二亚胺偶联和静电逐层沉积在聚己内酯非织造布上固定丝素蛋白和明胶：表征及细胞生长研究
Oliwia Jeznach,Onur Hasturk,Dorota Kołbuk et al.
Oliwia Jeznach et al.
Surface modification of scaffolds is a topic of great interest in tissue engineering due to the crucial role of scaffold surface in interactions with cells. In this study, we characterize electrospun poly(caprolactone) (PCL) nonwoven mats c...
Effects of Poly(β-Amino Ester) Networks on Macrophage Response In Vitro [0.03%]
聚β-氨基酯网络的网状结构对巨噬细胞反应的影响作用
Kayla Castillo-Aguilar,Aiden Walter,Stephanie J Bryant
Kayla Castillo-Aguilar
Poly(β-amino ester) or PBAE-based polymer networks are promising degradable biomaterials. This work investigated PBAEs formed from PBAE-diacrylate (PBAE-dA) macromers to assess how network chemistry and structure impact macrophages. PBAE-d...
Microgel-Based Immunomodulatory Biomaterials for Regulating Macrophage Polarization [0.03%]
基于微凝胶的免疫调控生物材料调节巨噬细胞极化
Cody Tuftee,Muhammad Rizwan
Cody Tuftee
Microgel-based biomaterials have gained increasing attention for their ability to modulate the immune response by regulating macrophage polarization, a key determinant in the transition from inflammation to tissue regeneration. Among these,...
Effect of Osteoblast-Extracellular Matrix-Functionalized Nanostructured Titanium Surface on Osteoblastic Cell Behavior [0.03%]
成骨细胞-细胞外基质功能化的纳米结构钛表面处理对成骨细胞行为的影响
Georgia Kors Quiles,Paola Gomes Souza,Maria Paula Oliveira Gomes et al.
Georgia Kors Quiles et al.
Nanostructured titanium (Ti) facilitates osteoblast differentiation by modulating various signaling pathways and may enhance osseointegration, potentially through its influence on the formation and remodeling of the extracellular matrix (EC...
Reduced Complement and Granulocyte Activation by α-Gal Knockout Porcine Pericardium for Bioprosthetic Heart Valves: A Pilot Hemocompatibility Study [0.03%]
α-半乳糖敲除猪心包降低生物心脏瓣膜的补体激活和中性粒细胞聚集（初步血相容性研究）
Claudia Dittfeld,Elisabeth Kemter,Barbara Kessler et al.
Claudia Dittfeld et al.
Xenogeneic pericardium is the main source for biological aortic valve prostheses. Immune responses to α-Gal epitopes and free aldehyde groups after glutaraldehyde (GA) fixation are responsible for the graft deterioration and the need for r...
pH-Sensitive Cationic Liposomes for Oridonin and siRNA Co-Delivery to Inhibit Triple-Negative Breast Cancer [0.03%]
用于联合递送奥利多因和siRNA抑制三阴性乳腺癌的pH敏感阳离子脂质体
Fangfang Wang,Qiong Yang,Xiaoliang Chen et al.
Fangfang Wang et al.
To investigate the therapeutic efficacy of co-delivering a small molecule compound and an interfering RNA in triple-negative breast cancer (TNBC), a disease characterized by poor prognosis, this study developed pH-sensitive nanocomposite ca...
Superelastic Ti-Zr-Nb-Sn Thin Films Fabricated by Magnetron Sputtering: Biocompatibility and Bacterial Biofilm Formation Assessment for Orthopedic Applications [0.03%]
用于骨科应用的磁控溅射制备的超级弹性Ti-Zr-Nb-Sn薄膜的生物相容性及生物膜形成评估
Hiroki Chigama,Thibaud Choquet,Pascale Vigneron et al.
Hiroki Chigama et al.
Nickel-titanium (NiTi) alloys are widely used in orthopedics because of their excellent mechanical properties; however, hypersensitivity remains a concern because of Ni ion release during long-term implantation. To address this issue, we ma...
Edible Sulfonated Soy Protein Microcarriers for Cultivated Meat Cell Expansion [0.03%]
用于培养肉细胞扩增的可食用磺化大豆蛋白微载体
Andrea C Filler,Alex S Kermani,Aurora Duan et al.
Andrea C Filler et al.
Microcarriers are essential in large-scale cell expansion for applications such as cultivated meat but are typically composed of non-edible materials, requiring additional cell retrieval steps. The ability to incorporate microcarriers into ...
ROS-Responsive Quercetin Nanoparticles Improve the Prognosis of Traumatic Brain Injury by Inhibiting Aberrant Nrf2-Keap1 Signaling Pathway Activation [0.03%]
ROS响应型白藜芦醇纳米粒通过抑制异常Nrf2信号通路激活改善颅脑损伤预后
YiFan Lei,Rongrong Dou,Cuihuan Ma et al.
YiFan Lei et al.
Traumatic brain injury (TBI) is one of the leading causes of mortality and disability worldwide, with secondary injury recognized as a critical therapeutic target. Quercetin (QR), a natural flavonoid, exerts antioxidant and anti-inflammator...