A Modular and Scalable FPGA Platform for Intelligent, High-Throughput Image-Activated Cell Sorting [0.03%]
一种模块化、可扩展的FPGA平台实现智能、高通量的图像激活细胞分选功能
Yan Ding,Jiehua Zhou,Ruiqi Xi et al.
Yan Ding et al.
Image-activated cell sorting (IACS) enables high-throughput cell classification by linking cellular morphology to physiology. While integrating advanced artificial intelligence (AI) can enhance the capture of subtle morphological heterogene...
Beyond PBMCs: Polymer-Based Cell Mimics for Robust TBNK Immunophenotyping Assay Validation [0.03%]
PBMC以外：用于稳健的TBNK免疫表型测定验证的聚合物基细胞模拟物
Swetha Pratyusha Gunturu,Subhanip Biswas,Armando Martinez et al.
Swetha Pratyusha Gunturu et al.
Flow cytometry-based TBNK immunophenotyping is widely used to assess immune status in research, clinical diagnostics, and cell therapy development. Biological control materials such as PBMCs often serve as physiologically relevant controls,...
Ryan Kmet,Shuchan Zhou,David Novo
Ryan Kmet
We model the process of computing all n - 1 $$ /left(n-1/right) $$ -element subsets of an n $$ n $$ -element set (representing a set of fluorescence minus one [FMO] controls) using only binary union operations. By representing this ...
Development and Validation of Flow Cytometry-Based Method to Quantify CD34/CD45+ Cells as a Release Criterion of Clinical-Grade Products for a Phase III Clinical Trial [0.03%]
Delphine Bouis,Aurélien Goubaud,Arthur Cormier et al.
Delphine Bouis et al.
We completed an international, multicenter, randomized, open-label Phase I/IIb trial assessing the safety and preliminary efficacy of transendocardial injection of autologous expanded CD34+ cells (ProtheraCytes) in patients after acute myoc...
Optimizing Cell Sorting Performance: A Comparative Study Utilizing Spectral Flow Cytometry [0.03%]
优化细胞分选性能：采用光谱流式细胞仪的比较研究
Jarina Pena DaMata,Randall Johnson,Iyadh Douagi
Jarina Pena DaMata
The introduction of full spectral technology in flow cytometry has facilitated access to an increasing number of markers to define cell subsets with higher precision. Cell sorting has a unique advantage to combine high throughput single cel...
CytoBatchFlagR: A Comprehensive Framework to Objectively Assess High-Parameter Cytometry Data for Batch Effects [0.03%]
CytoBatchFlagR：一种全面的框架，用于客观评估高参数细胞测量数据中的批次效应
Shruti Eswar,Zachary T Koenig,Amanda R Tursi et al.
Shruti Eswar et al.
Rapid advancements in mass and flow cytometry technologies have allowed researchers to generate and analyze high-dimensional single cell datasets, often utilizing upwards of 40 protein markers. Such high-parameter cytometry is increasingly ...
A Mass Cytometry-Based Blood Cell Phenotyping Workflow Enabling Inclusion of Resource-Limited and Rural Sites in Immune System Studies [0.03%]
一种基于高通量血液免疫细胞分析的表型 workflow，便于在免疫系统研究中纳入资源匮乏和农村地区站点
Natalie J Smith,Michael Cohen,Lauren Tracey et al.
Natalie J Smith et al.
Insight into disease detection and treatment through comprehensive immune phenotyping relies on the generation of high-quality data. However, the execution of robust immune monitoring in clinical trials by flow cytometry is complex due to l...
Gate Shape Matters [0.03%]
栅极形状有讲究
Yolanda D Mahnke,Bartek Rajwa
Yolanda D Mahnke
A Computational Workflow for Cell Line Profiling by Imaging Mass Cytometry [0.03%]
基于成像质谱细胞计数的细胞系分析计算流程
Alexandre Bouzekri,Amanda Esch,Olga Ornatsky
Alexandre Bouzekri
In single-cell spatial phenotyping biology, imaging mass cytometry (IMC) stands out as a cutting-edge, highly multiplexed technology driving discoveries across various disease areas. In vitro profiling relies on tumor-derived cancer cell li...
Superior Intracellular Detection of Cytokines, Transcription Factors, and Phosphoproteins by CyTOF Compared With Fluorescent Cytometry [0.03%]
与荧光流式细胞术相比，CyTOF在细胞内检测细胞因子、转录因子和磷酸化蛋白方面的优越性
Michael J Cohen,Erika L Smith-Mahoney,Madison Bailey et al.
Michael J Cohen et al.
Unraveling biological complexity, such as immune subset distribution in infectious disease(s), autoimmunity, or tumor heterogeneity, requires technologies capable of single-cell proteomic analysis such as flow cytometry. Surface phenotyping...