MTERF1 Regulates Podocyte Mitochondrial DNA Replication Impairment and Mitochondrial Dysfunction in Diabetic Nephropathy through the AMPK/mTOR Pathway [0.03%]
MTERF1通过AMPK/mTOR信号通路调节糖尿病肾病系膜细胞线粒体DNA复制障碍及功能异常
Haiying Tao,Ling&#x;an Yu
Haiying Tao
Objective: This study was carried out with an objective to clarify the mechanism of mitochondrial transcription termination factor 1 (MTERF1) in regulating mitochondrial DNA (mtDNA) replication and mitochondrial function ...
Suppression of PCBP1 Enhances PPARγ via TAK1 Modulation to Improve Glycemic and Lipid Metabolism Disorders in Gestational Diabetes Mellitus [0.03%]
PCBP1抑制通过TAK1调节改善妊娠糖尿病患者的血糖和血脂代谢紊乱及PPARγ表达增多
Xuemei Xia,Yan Chen
Xuemei Xia
Objective: Gestational diabetes mellitus (GDM) affects the health of pregnant women and their fetuses. Poly(C)-binding protein 1 (PCBP1), a multifunctional RNA-binding protein, is pivotal in maintaining cytosolic iron hom...
FAM111B as a Multi-Omics Biomarker for Diagnosis, Prognosis, and Immune Modulation in Colorectal Cancer [0.03%]
FAM111B作为结直肠癌诊断、预后和免疫调节的多组学生物标志物
Zhiqiang Zhu
Zhiqiang Zhu
Objective: Colorectal cancer (CRC) remains a leading cause of cancer mortality globally, necessitating novel biomarkers for early intervention. Although FAM111B - a gene implicated in DNA repair and cell cycle control - e...
Dexmedetomidine Regulates HMGB1 Transferred by HK-2 Cell-Derived Exosomes to Suppress Myocardial Cell Pyroptosis by Activating the TLR4 Signaling Pathway [0.03%]
右美托咪定通过激活TLR4信号通路调节HK-2细胞来源的外泌体转移HMGB1以抑制心肌细胞焦亡
Jingjing Zhang,Qiang Geng,Jinhui Sun et al.
Jingjing Zhang et al.
Objective: To investigate the effect of Dexmedetomidine (Dex) on myocardial cell pyroptosis by regulating HK-2 cell-derived exosomes and analyze its underlying mechanism. ...
Non-Sebaceous Lymphadenoma in the Parotid Gland: A Report of Two Cases with Immunohistochemical Study and a Literature Review [0.03%]
腮腺非脂质淋巴腺瘤两例报告及文献复习伴有免疫组化研究
Ruochen Wu,Shanshan Bai,Ya Zhang et al.
Ruochen Wu et al.
Non-sebaceous lymphadenoma (NSL) of the parotid gland is a rare benign tumor. During diagnosis, NSL may be confused with malignant tumors such as lymphoepithelial carcinoma, which can result in overtreatment. In this article, the clinical d...
Nasim Haghandish,Adel Kauzman,Nabil Ouatik et al.
Nasim Haghandish et al.
We present an 18-month-old boy with an exophytic mass in an unusual location, the right anterior-superior gingiva between deciduous teeth 5.3 and 5.4. Histopathologic and immunohistochemical investigations revealed a mesenchymal hamartoma (...
Case Reports
Annals of clinical and laboratory science. 2025 Sep;55(5):824-826. DOI: 2025
Construction of a Mortality Prediction Model for Acute Organophosphorus Pesticide Poisoning Patients Undergoing Hemoperfusion [0.03%]
血液灌流治疗急性有机磷中毒患者死亡风险预测模型的构建
Xinran Yang,Xiuxian Zang,Bin Nian et al.
Xinran Yang et al.
Objective: Organophosphorus pesticide poisoning (AOPP) leads to high mortality among patients. Hemoperfusion can remove organophosphates in the blood circulation and is the treatment of choice in these patients. However, ...
Obacunone Mitigates Ulcerative Colitis-Induced Colonic Epithelial Cell Injury by Activating Mitophagy via the PARP1/SIRT1 Signaling Pathway [0.03%]
OBACUNONE通过PARP1/SIRT1信号通路激活线粒体自噬缓解溃疡性结肠炎引起的结肠上皮细胞损伤
Zetao Wang,Yao Sun,Xiaohui Zhou et al.
Zetao Wang et al.
Objective: This study unveils how obacunone (OB) mitigates ulcerative colitis (UC)-induced colonic epithelial cell injury by activating mitophagy via the poly(ADP-ribose) polymerase 1 (PARP1)/sirtuin 1 (SIRT1) signaling p...
Explore the Function and Mechanisms of Triptolide in Tenascin-C Mediated Migration and Gemcitabine Resistance in Pancreatic Cancer [0.03%]
三七茋通过下调Tenascin-C介导的迁移和吉西他滨耐药在胰腺癌中的功能及机制探讨
Jun Cai,Xiumei Zhao,Xijing Li et al.
Jun Cai et al.
Objective: The extracellular matrix protein Tenascin-C (TNC) is known to promote the development of pancreatic cancer. The current study investigated the effect and mechanism of Triptolide (TP), a monomer component extrac...