Majid Mufaqam Syed-Abdul
Majid Mufaqam Syed-Abdul
Objective: Lacteal motion can be visualized in vivo, but quantitative analysis remains difficult because intravital intestinal imaging is affected by motion, focal instability, and baseline fluorescence variability. ...
Plantar Foot Microvascular Reactivity and Oxygenation in Type 2 Diabetes and Peripheral Artery Disease: An Exploratory Study [0.03%]
2型糖尿病伴周围动脉疾病的足底血管反应性和氧合的探索性研究
Josi Gallo,Allison Miller,Emily Chan et al.
Josi Gallo et al.
Objective: Microvascular dysfunction contributes to foot complications in type 2 diabetes (T2D) and peripheral artery disease (PAD), yet has been characterized primarily in non-plantar regions. We evaluated microvascular ...
Beyond Viral Control: Tenofovir's Hidden Impact on Blood-Brain Barrier Endothelial Cells [0.03%]
超越病毒控制：替诺福韦对血脑屏障内皮细胞的隐秘影响
Saarah Behardien,Khayelihle Brian Makhathini,Chontrelle Willemse et al.
Saarah Behardien et al.
The blood-brain barrier (BBB) is a dynamic endothelial interface that protects the brain from harmful agents while regulating molecular exchange. Human immunodeficiency virus (HIV) compromises BBB integrity, promoting neurological damage. A...
Carbon Dioxide Concentration Alters the Dynamics of Oxygen-Mediated Capillary Blood Flow Responses in Skeletal Muscle [0.03%]
二氧化碳分压改变骨骼肌氧气介导的毛细血管血流反应动力学
Alexander Folkins,Gaylene M Russell McEvoy,Graham M Fraser
Alexander Folkins
Hypothesis: We hypothesize that the dynamics of O2-mediated blood flow responses in skeletal muscle capillaries are altered under different tissue carbon dioxide concentrations ([CO2]) due to the interaction of overlappin...
Diabetes Upregulates BKCa Channels in Pulmonary Arterial Smooth Muscle by Altering the Local Control Mechanism of the Pore-Gate Domain [0.03%]
糖尿病通过改变孔道-闸门结构域的局部调控机制上调肺动脉平滑肌细胞的大电导钙激活钾通道BKCa
Vadym Sydorenko,Irina Ivanova,Dariia Dryn et al.
Vadym Sydorenko et al.
Objective: Large conductance calcium-activated potassium channels (BKCa) play an important role in the regulation of vascular tone. However, the properties of BKCa channels in smooth muscle of pulmonary arteries are poorl...
Evaluation of Red Blood Cell Biomechanics in the Setting of Cancer-Associated Anemia and Chemotherapy [0.03%]
评估癌症相关性贫血和化疗情况下的红细胞生物力学
Deirdre Finnigan,Nick Cruickshanks,George Ilbawi et al.
Deirdre Finnigan et al.
Introduction: Red blood cells (RBCs) possess distinct biomechanical properties that enable their survival and efficient oxygen delivery. Cancer-associated anemia, frequently compounded by chemotherapy, is a major clinical...
ZEB1 Modifies VE-Cadherin Signaling in Lymphatic Endothelial Cells [0.03%]
ZEB1修饰淋巴内皮细胞中的VE-钙粘蛋白信号转导
Nada S Ahmed,Joseph L Horder,Charles T Cresswell et al.
Nada S Ahmed et al.
Objective: Zinc finger E-box-binding homeobox 1 (ZEB1) is a transcription factor primarily known for its regulatory roles in epithelial-to-mesenchymal transition (EMT) and cell fate determination. Recent studies suggest t...
Anisodamine Hydrobromide Ameliorates Pulmonary Microcirculatory Dysfunction in Septic Rats [0.03%]
氢溴酸东莨菪碱改善脓毒症大鼠肺微循环障碍的作用研究
Yan-Chen Liu,Ting-Ting Xie,Xiao-Yi Wang et al.
Yan-Chen Liu et al.
Background: Pulmonary microcirculatory dysfunction is a hallmark of sepsis, contributing to hypoxemia, pulmonary edema, and multiple organ failure. Anisodamine hydrobromide (ADM), a natural alkaloid with anti-inflammatory...
The Relationship Between Sublingual Microcirculatory Structure and Frailty in Renal Transplant Candidates: Exploring Tortuosity & Endothelial Glycocalyx Biomarkers [0.03%]
舌下微循环结构与肾移植候选者的脆弱性的关系：探索迂曲度和内皮糖胺聚糖生物标志物的关系
Ryan A P Homes,Trent Payne,Fiona Giddens et al.
Ryan A P Homes et al.
Objective: This study investigated the relationship between sublingual microcirculatory tortuosity, frailty index scores, and endothelial glycocalyx blood biomarkers in individuals with chronic kidney disease (CKD). ...