Antimicrobial resistance in Ecuador, 2000-2024: a systematic review within a One Health framework [0.03%]
厄瓜多尔的抗菌药物耐药性（2000-2024年）：一项基于同一健康框架的系统评价
Carlos Bastidas-Caldes,Fernanda Hernández-Alomía,Francisco Bolaños et al.
Carlos Bastidas-Caldes et al.
Antimicrobial resistance (AMR) is a major global public health threat, particularly in low- and middle-income countries. In Ecuador, AMR research has expanded during the last two decades, but evidence remains fragmented and largely restrict...
Bacterial outer membrane vesicles in oral diseases: from pathogenic mediators to theranostic platforms [0.03%]
口腔疾病中的细菌外膜囊泡：从致病介体到治疗诊断平台
Yuluan Bu,Zixin Fan,Lu Li
Yuluan Bu
Bacterial outer membrane vesicles (bOMVs) are nanoscale structures derived from Gram-negative (G-) bacteria that play an important role in oral diseases. As key mediators of host-microbe interactions, bOMVs contribute to the pathogenesis of...
Antimicrobial peptides and enzymes: synergistic mechanisms and strategies for disrupting biofilm-associated infections [0.03%]
抗菌肽和酶：协同作用及破坏生物被膜相关感染的策略
Shivangi Dhavalkumar Shukla,Bragadish D Iyer
Shivangi Dhavalkumar Shukla
Medical biofilms are a significant problem in chronic diseases like diabetic ulcers that do not heal, infections of medical devices and CF. The extracellular polymeric matrix is a barrier to antibiotic penetration. In search of an alternati...
Microbial profiling through volatile organic compounds as a route toward rapid detection of bacterial infections [0.03%]
基于挥发性有机化合物的微生物表型分析在快速检测细菌感染中的应用初探
Susana P Costa,Adelaide Miranda,Pieter A A De Beule
Susana P Costa
Bacterial infections remain a critical global health challenge, particularly in clinical settings where antimicrobial resistance is rising. Rapid diagnostic tools are crucial for enabling timely therapeutic interventions and mitigating dise...
Noorulain Hyder,Muhammad Liaquat Raza
Noorulain Hyder
Stress may be defined as a nonspecific systemic response that occurs when the body is engaged by a variety of stimuli, which has the capacity to influence a number of different physiological systems of the body. Recent research has shown th...
Shuang Liu,Yanhua Yang,Ye Pan et al.
Shuang Liu et al.
Microbial communities play a critical role in human health, and their metabolic activities are directly implicated in the pathogenesis and progression of various diseases. Conventional detection methods for microbes and biomarkers, however,...
Mechanical determinants of bacterial collective behavior: from active turbulence to early biofilm organization [0.03%]
细菌集体行为的力学决定因素：从活性湍流到早期生物膜组织
Navinkumar Patil
Navinkumar Patil
During early colonization, motile bacteria can shift from independent swimming to coordinated collective states shaped by environmental mechanics, with consequences for subsequent biofilm development and tolerance. This critical review inte...
Maliha Rehman,Wasim Sajjad,Shichang Kang et al.
Maliha Rehman et al.
Permafrost, ground frozen for at least two consecutive years, covers nearly one-quarter of the Northern Hemisphere and hosts diverse microbial communities. Climate-driven thaw is releasing preserved microorganisms and genetic material into ...
Protease-driven approaches for wound eschar debridement and biofilm disruption: current advances, future prospects, and limitations [0.03%]
蛋白酶促伤口焦痂清创及生物被膜破坏的最新进展、未来前景和局限性
Julia Yunus,Khairunadwa Jemon,Shaza Eva Mohamad et al.
Julia Yunus et al.
Chronic wounds frequently develop eschar, a dense layer of necrotic tissue that impedes healing and fosters bacterial biofilm formation. Biofilms, protected within an extracellular polymeric substance, show high resistance to antimicrobial ...
Environmental regulation of pathogenicity islands by nucleoid-associated proteins in bacteria [0.03%]
参与细菌毒力岛调控的核仁相关蛋白研究进展
Harsh V Purohit,Joydeep Chakraborty
Harsh V Purohit
Pathogenicity islands (PAIs) are horizontally acquired genomic regions that encode virulence factors essential for bacterial pathogenicity. Their expression must be precisely regulated to avoid detrimental fitness costs outside the host and...