Microbial profiling through volatile organic compounds as a route toward rapid detection of bacterial infections [0.03%]
基于挥发性有机化合物的微生物表型分析在快速检测细菌感染中的应用初探
Susana P Costa,Adelaide Miranda,Pieter A A De Beule
Susana P Costa
Bacterial infections remain a critical global health challenge, particularly in clinical settings where antimicrobial resistance is rising. Rapid diagnostic tools are crucial for enabling timely therapeutic interventions and mitigating dise...
Noorulain Hyder,Muhammad Liaquat Raza
Noorulain Hyder
Stress may be defined as a nonspecific systemic response that occurs when the body is engaged by a variety of stimuli, which has the capacity to influence a number of different physiological systems of the body. Recent research has shown th...
Shuang Liu,Yanhua Yang,Ye Pan et al.
Shuang Liu et al.
Microbial communities play a critical role in human health, and their metabolic activities are directly implicated in the pathogenesis and progression of various diseases. Conventional detection methods for microbes and biomarkers, however,...
Mechanical determinants of bacterial collective behavior: from active turbulence to early biofilm organization [0.03%]
细菌集体行为的力学决定因素：从活性湍流到早期生物膜组织
Navinkumar Patil
Navinkumar Patil
During early colonization, motile bacteria can shift from independent swimming to coordinated collective states shaped by environmental mechanics, with consequences for subsequent biofilm development and tolerance. This critical review inte...
Maliha Rehman,Wasim Sajjad,Shichang Kang et al.
Maliha Rehman et al.
Permafrost, ground frozen for at least two consecutive years, covers nearly one-quarter of the Northern Hemisphere and hosts diverse microbial communities. Climate-driven thaw is releasing preserved microorganisms and genetic material into ...
Protease-driven approaches for wound eschar debridement and biofilm disruption: current advances, future prospects, and limitations [0.03%]
蛋白酶促伤口焦痂清创及生物被膜破坏的最新进展、未来前景和局限性
Julia Yunus,Khairunadwa Jemon,Shaza Eva Mohamad et al.
Julia Yunus et al.
Chronic wounds frequently develop eschar, a dense layer of necrotic tissue that impedes healing and fosters bacterial biofilm formation. Biofilms, protected within an extracellular polymeric substance, show high resistance to antimicrobial ...
Environmental regulation of pathogenicity islands by nucleoid-associated proteins in bacteria [0.03%]
参与细菌毒力岛调控的核仁相关蛋白研究进展
Harsh V Purohit,Joydeep Chakraborty
Harsh V Purohit
Pathogenicity islands (PAIs) are horizontally acquired genomic regions that encode virulence factors essential for bacterial pathogenicity. Their expression must be precisely regulated to avoid detrimental fitness costs outside the host and...
New strains, new threats: the rise of atypical non-typhoidal Salmonella serovars and what it means for global health [0.03%]
新血清型，新威胁：非典型伤寒沙门氏菌血清型的崛起及其对全球健康的影响
Amy Campbell,Archie Harber,Séamus Fanning et al.
Amy Campbell et al.
Salmonella is one of the most common causes of foodborne illness worldwide. These infections, in turn, exert an impact on both industry and healthcare settings. Salmonella is the agent that causes salmonellosis, a gastroenteric infection. O...
Ting Chu,Yongjie Wang
Ting Chu
Giant viruses constitute a remarkable group of large double-stranded DNA (dsDNA) viruses distinguished by their exceptional structural complexity and genomic features. Their genomes can reach 2.8 Mb, encoding hundreds of proteins, and virio...
Anti- Candida albicans natural products: convergent technologies revolutionizing discovery from bioactivity assessment to targeted mechanisms [0.03%]
抗白色念珠菌的天然产物：从生物活性评估到靶向机制的发现的汇聚技术革命
Di Zhang,Xiaoxing Liu,Xueqin Zhao et al.
Di Zhang et al.
Candida albicans represents a critical opportunistic fungal pathogen. The escalating prevalence of drug resistance necessitates urgent development of novel antifungal therapeutics. Natural products, characterized by structural diversity and...