CLC chloride channels and transporters: from genes to protein structure, pathology and physiology [0.03%]
从基因到蛋白质结构、病理和生理机能的氯通道和转运蛋白研究进展：CLC氯通道和转运蛋白研究进展
Thomas J Jentsch
Thomas J Jentsch
CLC genes are expressed in species from bacteria to human and encode Cl(-)-channels or Cl(-)/H(+)-exchangers. CLC proteins assemble to dimers, with each monomer containing an ion translocation pathway. Some mammalian isoforms need essential...
Jillian R Brown,Brett E Crawford,Jeffrey D Esko
Jillian R Brown
Glycans, the carbohydrate chains of glycoproteins, proteoglycans, and glycolipids, represent a relatively unexploited area for drug development compared with other macromolecules. This review describes the major classes of glycans synthesiz...
Minghong Ma
Minghong Ma
Most animals have evolved multiple olfactory systems to detect general odors as well as social cues. The sophistication and interaction of these systems permit precise detection of food, danger, and mates, all crucial elements for survival....
Role of type 2C protein phosphatases in growth regulation and in cellular stress signaling [0.03%]
ⅡC型蛋白磷酸酶在生长调控和细胞压力信号传导中的作用
Twan Lammers,Sara Lavi
Twan Lammers
A number of interesting features, phenotypes, and potential clinical applications have recently been ascribed to the type 2C family of protein phosphatases. Thus far, 16 different PP2C genes have been identified in the human genome, encodin...