Invertebrate learning and memory: Fifty years of olfactory conditioning of the proboscis extension response in honeybees [0.03%]
无脊椎动物的学习和记忆：蜜蜂嗅觉条件反射调控吻伸展反应研究五十周年纪念综述
Martin Giurfa,Jean-Christophe Sandoz
Martin Giurfa
The honeybee Apis mellifera has emerged as a robust and influential model for the study of classical conditioning, thanks to the existence of a powerful Pavlovian conditioning protocol, the olfactory conditioning of the proboscis extension ...
What a nostril knows: olfactory nerve-evoked AMPA responses increase while NMDA responses decrease at 24-h post-training for lateralized odor preference memory in neonate rat [0.03%]
鼻子知道什么：24小时侧化气味偏好的训练后，嗅觉神经诱发的AMPA反应增加而NMDA反应减少
Qi Yuan,Carolyn W Harley
Qi Yuan
Increased AMPA signaling is proposed to mediate long-term memory. Rat neonates acquire odor preferences in a single olfactory bulb if one nostril is occluded at training. Memory testing here confirmed that only trained bulbs support increas...
Single prolonged stress disrupts retention of extinguished fear in rats [0.03%]
单一长时间压力会破坏大鼠消退恐惧的保留效果
Dayan Knox,Sophie A George,Christopher J Fitzpatrick et al.
Dayan Knox et al.
Clinical research has linked post-traumatic stress disorder (PTSD) with deficits in fear extinction. However, it is not clear whether these deficits result from stress-related changes in the acquisition or retention of extinction or in the ...
Transgenic expression of ZBP1 in neurons suppresses cocaine-associated conditioning [0.03%]
神经元转基因表达ZBP1可抑制cocaine相关条件作用
Kyle A B Lapidus,Chiso Nwokafor,Daniel Scott et al.
Kyle A B Lapidus et al.
To directly address whether regulating mRNA localization can influence animal behavior, we created transgenic mice that conditionally express Zipcode Binding Protein 1 (ZBP1) in a subset of neurons in the brain. ZBP1 is an RNA-binding prote...
G(o) activation is required for both appetitive and aversive memory acquisition in Drosophila [0.03%]
G(o)激活在果蝇获得愉悦和厌恶记忆过程中都是必需的
Adrian Madalan,Xiao Yang,Jacob Ferris et al.
Adrian Madalan et al.
Heterotrimeric G(o) is an abundant brain protein required for negatively reinforced short-term associative olfactory memory in Drosophila. G(o) is the only known substrate of the S1 subunit of pertussis toxin (PTX) in fly, and acute express...
Annette Jeneson,Larry R Squire
Annette Jeneson
Early studies of memory-impaired patients with medial temporal lobe (MTL) damage led to the view that the hippocampus and related MTL structures are involved in the formation of long-term memory and that immediate memory and working memory ...
Myosin II motor activity in the lateral amygdala is required for fear memory consolidation [0.03%]
侧杏仁体内肌球蛋白II的酶活性对于恐惧记忆的巩固是必需的
Cristin F Gavin,Maria D Rubio,Erica Young et al.
Cristin F Gavin et al.
Learning induces dynamic changes to the actin cytoskeleton that are required to support memory formation. However, the molecular mechanisms that mediate filamentous actin (F-actin) dynamics during learning and memory are poorly understood. ...
Hippocampus is required for paired associate memory with neither delay nor trial uniqueness [0.03%]
海马是配对联想记忆所必需的，无论是否具有延迟或试验唯一性
Jinah Yoon,Yeran Seo,Jangjin Kim et al.
Jinah Yoon et al.
Cued retrieval of memory is typically examined with delay when testing hippocampal functions, as in delayed matching-to-sample tasks. Equally emphasized in the literature, on the other hand, is the hippocampal involvement in making arbitrar...
Exaggerated NMDA mediated LTD in a mouse model of Down syndrome and pharmacological rescuing by memantine [0.03%]
唐氏综合征小鼠模型中夸大存在的NMDA受体介导的长时程抑制及其用美金刚的药理学干预
Jonah J Scott-McKean,Alberto C S Costa
Jonah J Scott-McKean
The Ts65Dn mouse is the best-studied animal model for Down syndrome. In the experiments described here, NMDA-mediated or mGluR-mediated LTD was induced in the CA1 region of hippocampal slices from Ts65Dn and euploid control mice by bath app...
Bidirectional plasticity in striatonigral synapses: a switch to balance direct and indirect basal ganglia pathways [0.03%]
纹状体黑质突触的双向可塑性：直接通路和间接通路平衡转换的开关机制
Jose J Aceves,Pavel E Rueda-Orozco,Ricardo Hernandez-Martinez et al.
Jose J Aceves et al.
There is no hypothesis to explain how direct and indirect basal ganglia (BG) pathways interact to reach a balance during the learning of motor procedures. Both pathways converge in the substantia nigra pars reticulata (SNr) carrying the res...