Functional specialization within the striatum along both the dorsal/ventral and anterior/posterior axes during associative learning via reward and punishment [0.03%]
纹状体在奖励和惩罚相关学习过程中背腹轴和前后轴的功能特化
Aaron T Mattfeld,Mark A Gluck,Craig E L Stark
Aaron T Mattfeld
The goal of the present study was to elucidate the role of the human striatum in learning via reward and punishment during an associative learning task. Previous studies have identified the striatum as a critical component in the neural cir...
Interaction between the basolateral amygdala and dorsal hippocampus is critical for cocaine memory reconsolidation and subsequent drug context-induced cocaine-seeking behavior in rats [0.03%]
侧隔核与海马区的相互作用对可卡因记忆再巩固及后续可卡因求药行为的影响critical for cocaine memory reconsolidation and subsequent drug context-induced cocaine-seeking behavior in rats
Audrey M Wells,Heather C Lasseter,Xiaohu Xie et al.
Audrey M Wells et al.
Contextual stimulus control over instrumental drug-seeking behavior relies on the reconsolidation of context-response-drug associative memories into long-term memory storage following retrieval-induced destabilization. According to previous...
AMPA receptor endocytosis in rat perirhinal cortex underlies retrieval of object memory [0.03%]
大鼠腹内侧前额叶皮层AMPAR内吞作用参与客体记忆的提取
Brittany N Cazakoff,John G Howland
Brittany N Cazakoff
Mechanisms consistent with long-term depression in the perirhinal cortex (PRh) play a fundamental role in object recognition memory; however, whether AMPA receptor endocytosis is involved in distinct phases of recognition memory is not know...
Context fear learning specifically activates distinct populations of neurons in amygdala and hypothalamus [0.03%]
情境恐惧学习特异性激活杏仁核和下丘脑的不同神经元群体
Lidia Trogrlic,Yvette M Wilson,Andrew G Newman et al.
Lidia Trogrlic et al.
The identity and distribution of neurons that are involved in any learning or memory event is not known. In previous studies, we identified a discrete population of neurons in the lateral amygdala that show learning-specific activation of a...
Neural circuitry and plasticity mechanisms underlying delay eyeblink conditioning [0.03%]
时间延缓眨眼条件反射的神经环路及其可塑性机制研究
John H Freeman,Adam B Steinmetz
John H Freeman
Pavlovian eyeblink conditioning has been used extensively as a model system for examining the neural mechanisms underlying associative learning. Delay eyeblink conditioning depends on the intermediate cerebellum ipsilateral to the condition...
Aversive olfactory learning and associative long-term memory in Caenorhabditis elegans [0.03%]
秀丽杆线虫中的厌恶型嗅觉学习和联想长期记忆反应
Hisayuki Amano,Ichiro N Maruyama
Hisayuki Amano
The nematode Caenorhabditis elegans (C. elegans) adult hermaphrodite has 302 invariant neurons and is suited for cellular and molecular studies on complex behaviors including learning and memory. Here, we have developed protocols for classi...
A behavior-based circuit model of how outcome expectations organize learned behavior in larval Drosophila [0.03%]
基于行为的电路模型：果蝇幼虫如何根据预期结果组织习得行为
Michael Schleyer,Timo Saumweber,Wiebke Nahrendorf et al.
Michael Schleyer et al.
Drosophila larvae combine a numerically simple brain, a correspondingly moderate behavioral complexity, and the availability of a rich toolbox for transgenic manipulation. This makes them attractive as a study case when trying to achieve a ...
Retention and extinction of delay eyeblink conditioning are modulated by central cannabinoids [0.03%]
中枢性大麻素对延时眨眼条件反射的巩固和消退有调节作用
Adam B Steinmetz,John H Freeman
Adam B Steinmetz
Rats administered the cannabinoid agonist WIN55,212-2 or the antagonist SR141716A exhibit marked deficits during acquisition of delay eyeblink conditioning, as noted by Steinmetz and Freeman in an earlier study. However, the effects of thes...
A protein synthesis and nitric oxide-dependent presynaptic enhancement in persistent forms of long-term potentiation [0.03%]
持久性长期增强的蛋白质合成和一氧化氮依赖性的突触前增强作用
Victoria P A Johnstone,Clarke R Raymond
Victoria P A Johnstone
Long-term potentiation (LTP) is an important process underlying learning and memory in the brain. At CA3-CA1 synapses in the hippocampus, three discrete forms of LTP (LTP1, 2, and 3) can be differentiated on the basis of maintenance and ind...
Dorsal and ventral striatal protein synthesis inhibition affect reinforcer valuation but not the consolidation of instrumental learning [0.03%]
背侧和腹侧纹状体蛋白合成抑制影响强化物的估值但不影响工具性学习的巩固
Sietse Jonkman,Barry J Everitt
Sietse Jonkman
The evidence for a role of the striatum in the acquisition of uncued instrumental responding is ambiguous. It has been shown that post-session infusions of anisomycin into the core of the nucleus accumbens (NAcc) impaired instrumental acqui...