The medial dorsal thalamic nucleus and the medial prefrontal cortex of the rat function together to support associative recognition and recency but not item recognition [0.03%]
大鼠内侧背侧丘脑核和内侧前额叶皮层共同作用支持联想识别和近因效应但不支持项目识别
Laura Cross,Malcolm W Brown,John P Aggleton et al.
Laura Cross et al.
In humans recognition memory deficits, a typical feature of diencephalic amnesia, have been tentatively linked to mediodorsal thalamic nucleus (MD) damage. Animal studies have occasionally investigated the role of the MD in single-item reco...
Significance of the centrally expressed TRP channel painless in Drosophila courtship memory [0.03%]
中枢表达的瞬时受体电位通道painless在果蝇求偶记忆中的作用意义
Takaomi Sakai,Shoma Sato,Hiroshi Ishimoto et al.
Takaomi Sakai et al.
Considerable evidence has demonstrated that transient receptor potential (TRP) channels play vital roles in sensory neurons, mediating responses to various environmental stimuli. In contrast, relatively little is known about how TRP channel...
Two waves of transcription are required for long-term memory in the honeybee [0.03%]
蜜蜂的长期记忆需要两次转录过程
Damien Lefer,Emmanuel Perisse,Benoît Hourcade et al.
Damien Lefer et al.
Storage of information into long-term memory (LTM) usually requires at least two waves of transcription in many species. However, there is no clear evidence of this phenomenon in insects, which are influential models for memory studies. We ...
Functional roles of neurotransmitters and neuromodulators in the dorsal striatum [0.03%]
背侧纹状体中神经递质和神经调质的功能作用
Jeehaeh Do,Jae-Ick Kim,Joseph Bakes et al.
Jeehaeh Do et al.
The dorsal striatum, with its functional microcircuits galore, serves as the primary gateway of the basal ganglia and is known to play a key role in implicit learning. Initially, excitatory inputs from the cortex and thalamus arrive on the ...
The E3 ligase APC/C-Cdh1 is required for associative fear memory and long-term potentiation in the amygdala of adult mice [0.03%]
泛素连接酶APC/C-Cdh1是成年小鼠海马CA1和杏仁核的长时程增强以及情境恐惧记忆形成的必要条件
Joseph E Pick,Marcos Malumbres,Eric Klann
Joseph E Pick
The anaphase promoting complex/cyclosome (APC/C) is an E3 ligase regulated by Cdh1. Beyond its role in controlling cell cycle progression, APC/C-Cdh1 has been detected in neurons and plays a role in long-lasting synaptic plasticity and long...
Cholinergic modulation during acquisition of olfactory fear conditioning alters learning and stimulus generalization in mice [0.03%]
胆碱能调节对小鼠获得嗅觉恐惧条件反射和刺激泛化的影响
Eloisa Pavesi,Allison Gooch,Elizabeth Lee et al.
Eloisa Pavesi et al.
We investigated the role of cholinergic neurotransmission in olfactory fear learning. Mice receiving pairings of odor and foot shock displayed fear to the trained odor the following day. Pretraining injections of the nicotinic antagonist me...
Effects of aversive stimuli beyond defensive neural circuits: reduced excitability in an identified neuron critical for feeding in Aplysia [0.03%]
不良刺激对防御性神经回路以外的影响：阿氏虫进食中关键神经元兴奋性的降低
Maria E Shields-Johnson,John S Hernandez,Cody Torno et al.
Maria E Shields-Johnson et al.
In Aplysia, repeated trials of aversive stimuli produce long-term sensitization (LTS) of defensive reflexes and suppression of feeding. Whereas the cellular underpinnings of LTS have been characterized, the mechanisms of feeding suppression...
Gustatory habituation in Drosophila relies on rutabaga (adenylate cyclase)-dependent plasticity of GABAergic inhibitory neurons [0.03%]
果蝇味觉习惯化依赖于rutabaga（腺苷酸环化酶）介导的抑制性神经元的可塑性
Pushkar Paranjpe,Veronica Rodrigues,K VijayRaghavan et al.
Pushkar Paranjpe et al.
In some situations, animals seem to ignore stimuli which in other contexts elicit a robust response. This attenuation in behavior, which enables animals to ignore a familiar, unreinforced stimulus, is called habituation. Despite the ubiquit...
Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP [0.03%]
胶质细胞GLT-1谷氨酸转运与晚期长时程增强的关系研究
Juan D Pita-Almenar,Shengwei Zou,Costa M Colbert et al.
Juan D Pita-Almenar et al.
Na⁺-dependent high-affinity glutamate transporters have important roles in the maintenance of basal levels of glutamate and clearance of glutamate during synaptic transmission. Interestingly, several studies have shown that basal glutamate...
Lauren J Gottlieb,Jenny Wong,Marianne de Chastelaine et al.
Lauren J Gottlieb et al.
Functional magnetic resonance imaging (fMRI) was employed to identify neural regions engaged during the encoding of contextual features belonging to different modalities. Subjects studied objects that were presented to the left or right of ...
Randomized Controlled Trial
Learning & memory (Cold Spring Harbor, N.Y.). 2012 Nov 19;19(12):605-14. DOI:10.1101/lm.027631.112 2012