Effects of number of items and interval length on the acquisition of temporal order discrimination in radial maze in rats [0.03%]
大鼠在径向迷宫中获得时间顺序辨别受项目数和间隔长度的影响
Manami Sugita,Kazuo Yamada,Yukio Ichitani
Manami Sugita
Temporal order discrimination in rats was analyzed using a radial maze. The task consisted of a study phase in which two to five items (arms) were presented sequentially and, after a delay, a test phase in which two of these were simultaneo...
Ramón H Lima,Andressa Radiske,Cristiano A Köhler et al.
Ramón H Lima et al.
Late post-training activation of the ventral tegmental area (VTA)-hippocampus dopaminergic loop controls the entry of information into long-term memory (LTM). Nicotinic acetylcholine receptors (nAChR) modulate VTA function, but their involv...
p300/CBP histone acetyltransferase activity is required for newly acquired and reactivated fear memories in the lateral amygdala [0.03%]
外侧杏仁体中P300/CBP组蛋白乙酰转移酶活性是新获得和被激活的恐惧记忆所必需的
Stephanie A Maddox,Casey S Watts,Glenn E Schafe
Stephanie A Maddox
Modifications in chromatin structure have been widely implicated in memory and cognition, most notably using hippocampal-dependent memory paradigms including object recognition, spatial memory, and contextual fear memory. Relatively little ...
The FMRFamide-related neuropeptide FLP-20 is required in the mechanosensory neurons during memory for massed training in C. elegans [0.03%]
秀丽隐杆线虫机械感觉神经元中的一个与FMRFamide相关的神经肽FLP-20在密集训练型记忆中是必需的
Chris Li,Tiffany A Timbers,Jacqueline K Rose et al.
Chris Li et al.
Lasting memories are likely to result from a lasting change in neurotransmission. In the nematode Caenorhabditis elegans, spaced training with a tap stimulus induces habituation to the tap that lasts for >24 h and is dependent on glutamate ...
Timing and cue competition in conditioning of the nictitating membrane response of the rabbit (Oryctolagus cuniculus) [0.03%]
兔子结膜反应条件作用的时间和提示竞争性研究(Oryctolagus cuniculus)
E James Kehoe,Elliot A Ludvig,Richard S Sutton
E James Kehoe
Rabbits were classically conditioned using compounds of tone and light conditioned stimuli (CSs) presented with either simultaneous onsets (Experiment 1) or serial onsets (Experiment 2) in a delay conditioning paradigm. Training with the si...
Optimization of apparatus design and behavioral measures for the assessment of visuo-spatial learning and memory of mice on the Barnes maze [0.03%]
优化视觉空间学习记忆巴恩斯迷宫实验装置的设计及行为学指标选择
Timothy P O&#x;Leary,Richard E Brown
Timothy P O&#x;Leary
We have previously shown that apparatus design can affect visual-spatial cue use and memory performance of mice on the Barnes maze. The present experiment extends these findings by determining the optimal behavioral measures and test proced...
Perirhinal and postrhinal, but not lateral entorhinal, cortices are essential for acquisition of trace eyeblink conditioning [0.03%]
旁回纹状皮质和后回纹状皮质而非侧内嗅皮质对迹痕眼睑条件反射获得至关重要
Eugénie E Suter,Craig Weiss,John F Disterhoft
Eugénie E Suter
The acquisition of temporal associative tasks such as trace eyeblink conditioning is hippocampus-dependent, while consolidated performance is not. The parahippocampal region mediates much of the input and output of the hippocampus, and peri...
Role of medial prefrontal cortex Narp in the extinction of morphine conditioned place preference [0.03%]
内侧前额叶皮层Narp在吗啡条件位置偏好的消退中的作用研究
Ashley M Blouin,Sungho Han,Anne M Pearce et al.
Ashley M Blouin et al.
Narp knockout (KO) mice demonstrate an impaired extinction of morphine conditioned place preference (CPP). Because the medial prefrontal cortex (mPFC) has been implicated in extinction learning, we tested whether Narp cells in this region p...
Iva B Zovkic,Mikael C Guzman-Karlsson,J David Sweatt
Iva B Zovkic
Understanding the cellular and molecular mechanisms underlying the formation and maintenance of memories is a central goal of the neuroscience community. It is well regarded that an organism's ability to lastingly adapt its behavior in resp...
Appetitive Pavlovian goal-tracking memories reconsolidate only under specific conditions [0.03%]
appetitive帕夫洛夫式目标追踪记忆仅在特定条件下重新巩固
Amy C Reichelt,Jonathan L C Lee
Amy C Reichelt
Despite extensive evidence that appetitive memories undergo reconsolidation, two notable failures to observe reconsolidation have been reported: instrumental responding and goal-tracking. However, these studies do not provide conclusive evi...