Oriane Turrel,Lili Gao,Stephan J Sigrist
Oriane Turrel
The intricate molecular and structural sequences guiding the formation and consolidation of memories within neuronal circuits remain largely elusive. In this study, we investigate the roles of two pivotal presynaptic regulators, the small G...
Ivy Chi Wai Chan,Nannan Chen,John Hernandez et al.
Ivy Chi Wai Chan et al.
How does the brain translate sensory information into complex behaviors? With relatively small neuronal numbers, readable behavioral outputs, and an unparalleled genetic toolkit, the Drosophila mushroom body (MB) offers an excellent model t...
Roles of feedback and feed-forward networks of dopamine subsystems: insights from Drosophila studies [0.03%]
多巴胺子系统反馈和前馈网络的作用：来自果蝇研究的启示
Andrew M Davidson,Toshihide Hige
Andrew M Davidson
Across animal species, dopamine-operated memory systems comprise anatomically segregated, functionally diverse subsystems. Although individual subsystems could operate independently to support distinct types of memory, the logical interplay...
Cognitive limits of larval Drosophila: testing for conditioned inhibition, sensory preconditioning, and second-order conditioning [0.03%]
果蝇幼虫的认知极限：检测条件性抑制、感觉预处理和二级条件反射
Edanur Sen,Amira El-Keredy,Nina Jacob et al.
Edanur Sen et al.
Drosophila larvae are an established model system for studying the mechanisms of innate and simple forms of learned behavior. They have about 10 times fewer neurons than adult flies, and it was the low total number of their neurons that all...
Mareike Selcho
Mareike Selcho
Octopamine, the functional analog of noradrenaline, modulates many different behaviors and physiological processes in invertebrates. In the central nervous system, a few octopaminergic neurons project throughout the brain and innervate almo...
Hans V Alten
Hans V Alten
Glial metabolism versatility regulates mushroom body-driven behavioral output in Drosophila [0.03%]
胶质细胞代谢的可塑性调节果蝇蘑菇体驱动的行为输出
Ruchira Basu,Thomas Preat,Pierre-Yves Plaçais
Ruchira Basu
Providing metabolic support to neurons is now recognized as a major function of glial cells that is conserved from invertebrates to vertebrates. However, research in this field has focused for more than two decades on the relevance of lacta...
Caleb Larnerd,Neha Kachewar,Fred W Wolf
Caleb Larnerd
Drug addiction and the circuitry for learning and memory are intimately intertwined. Drugs of abuse create strong, inappropriate, and lasting memories that contribute to many of their destructive properties, such as continued use despite ne...
Amoolya Sai Dwijesha,Akhila Eswaran,Jacob A Berry et al.
Amoolya Sai Dwijesha et al.
In this review, we aggregated the different types of learning and memory paradigms developed in adult Drosophila and attempted to assess the similarities and differences in the neural mechanisms supporting diverse types of memory. The simpl...
Beyond prediction error: 25 years of modeling the associations formed in the insect mushroom body [0.03%]
超越预测误差：昆虫蘑菇身体联系建模的25年研究
Barbara Webb
Barbara Webb
The insect mushroom body has gained increasing attention as a system in which the computational basis of neural learning circuits can be unraveled. We now understand in detail the key locations in this circuit where synaptic associations ar...