Andrew J D Nelson,Emma L Hindley,Josephine E Haddon et al.
Andrew J D Nelson et al.
By virtue of its frontal and hippocampal connections, the retrosplenial cortex is uniquely placed to support cognition. Here, we tested whether the retrosplenial cortex is required for frontal tasks analogous to the Stroop Test, i.e., for t...
Stephanie A Carmack,Kristin K Howell,Kleou Rasaei et al.
Stephanie A Carmack et al.
Methylphenidate (MPH), introduced more than 60 years ago, accounts for two-thirds of current prescriptions for attention deficit hyperactivity disorder (ADHD). Although many studies have modeled MPH's effect on executive function, almost no...
A bout of voluntary running enhances context conditioned fear, its extinction, and its reconsolidation [0.03%]
一次性自由跑步增强条件化恐惧、消退及再巩固
Joyce Siette,Amy C Reichelt,R Frederick Westbrook
Joyce Siette
Three experiments used rats to examine the effect of a single bout of voluntary activity (wheel running) on the acquisition, extinction, and reconsolidation of context conditioned fear. In Experiment 1, rats provided with access to a wheel ...
The role of rewarding and novel events in facilitating memory persistence in a separate spatial memory task [0.03%]
奖赏和新颖事件在独立空间记忆任务中促进记忆巩固的作用
Beatrice Salvetti,Richard G M Morris,Szu-Han Wang
Beatrice Salvetti
Many insignificant events in our daily life are forgotten quickly but can be remembered for longer when other memory-modulating events occur before or after them. This phenomenon has been investigated in animal models in a protocol in which...
Persistent prelimbic cortex activity contributes to enhanced learned fear expression in females [0.03%]
前扣带回皮层的持续活动增加导致女性产生过度的习得恐惧反应
Georgina E Fenton,Amelia K Pollard,David M Halliday et al.
Georgina E Fenton et al.
Anxiety disorders, such as post-traumatic stress, are more prevalent in women and are characterized by impaired inhibition of learned fear and medial prefrontal cortex (mPFC) dysfunction. Here we examined sex differences in fear extinction ...
Memory destabilization is critical for the success of the reactivation-extinction procedure [0.03%]
记忆不稳定对重新激活-消退程序的成功至关重要
Marcelo E Piñeyro,Roque I Ferrer Monti,Joaquín M Alfei et al.
Marcelo E Piñeyro et al.
It has been suggested that, unlike pure extinction which typically results in the return of the fear response under a variety of circumstances, memory reactivation followed by extinction can attenuate the reemergence of conditioned fear. Th...
Short- and long-term memories formed upon backward conditioning in honeybees (Apis mellifera) [0.03%]
后向经典条件作用在蜜蜂的短期和长期记忆形成中的作用（Apis mellifera）
Johannes Felsenberg,Jenny Aino Plath,Steven Lorang et al.
Johannes Felsenberg et al.
In classical conditioning, the temporal sequence of stimulus presentations is critical for the association between the conditioned stimulus (CS) and the unconditioned stimulus (US). In forward conditioning, the CS precedes the US and is lea...
Spatial memory: behavioral determinants of persistence in the watermaze delayed matching-to-place task [0.03%]
空间记忆：水迷宫延迟匹配定位任务中行为持续性的决定因素
Bruno M da Silva,Tobias Bast,Richard G M Morris
Bruno M da Silva
The watermaze delayed matching-to-place (DMP) task was modified to include probe trials, to quantify search preference for the correct place. Using a zone analysis of search preference, a gradual decay of one-trial memory in rats was observ...
James A Bisby,Neil Burgess
James A Bisby
The formation of associations between items and their context has been proposed to rely on mechanisms distinct from those supporting memory for a single item. Although emotional experiences can profoundly affect memory, our understanding of...
Activity in prelimbic cortex subserves fear memory reconsolidation over time [0.03%]
前扣带回皮质的活动介导恐惧记忆再巩固的时效性变化规律
Cristina A J Stern,Lucas Gazarini,Ana C Vanvossen et al.
Cristina A J Stern et al.
The prelimbic cortex has been implicated in the consolidation of previously learned fear. Herein, we report that temporarily inactivating this medial prefrontal cortex subregion with the GABAA agonist muscimol (4.0 nmol in 0.2 μL per hemis...