Exploring stress hormone effects on memory specificity and strength in mice using the dual-event inhibitory avoidance task [0.03%]
利用双重事件禁令回避任务在小鼠中探索应激激素对记忆特异性和强度的影响
Sevgi Bahtiyar,Kubra Gulmez Karaca,Marloes J A G Henckens et al.
Sevgi Bahtiyar et al.
Stressful and emotionally arousing experiences induce the release of noradrenergic and glucocorticoid hormones that synergistically strengthen memories but differentially regulate qualitative aspects of memory. This highlights the need for ...
Optogenetic inhibition of the locus coeruleus blocks vagus nerve stimulation-induced enhancement of extinction of conditioned fear in rats [0.03%]
光遗传学抑制蓝斑阻断迷走神经刺激诱导的条件恐惧消退增强效应(大鼠)
Debora R Calderon-Williams,Rimenez Rodrigues de Souza,Ching T Tseng et al.
Debora R Calderon-Williams et al.
Vagus nerve stimulation (VNS) is a therapeutic intervention previously shown to enhance fear extinction in rats. VNS is approved for use in humans for the treatment of epilepsy, depression, and stroke, and it is currently under investigatio...
Shaping behaviors through social experience and their proposed sensitivity to stress [0.03%]
社会经验和压力塑造行为的敏感性
J Amiel Rosenkranz
J Amiel Rosenkranz
Mammals have evolved with a range of innate drives, such as thirst and hunger, that promote motivated behaviors to ensure survival. A drive for social engagement promotes social interaction and bond formation. While a stable social environm...
Stress enhances memory for previously encoded events depending on stressor recall [0.03%]
应激通过唤起增强先前编码事件的记忆
Antonia Lilja,Guillen Fernandez,Lars Schwabe
Antonia Lilja
Stressful events are typically well remembered, but their effects on memory for surrounding neutral events and the underlying mechanisms remain less clear. We hypothesized that stress would enhance memory for events surrounding the stressor...
High and low current perceived stress associated with enhanced emotional mnemonic discrimination [0.03%]
高压力和低压力下的感知压力与情感记忆辨别的增强相关性研究
Rishi Vas,Taylor Phillips,Lorena A Ferguson et al.
Rishi Vas et al.
Stress can have profound impacts on memory. However, the directionality of stress effects on memory varies widely across studies, some showing enhancement while others showing impairment. This variability has been attributed to the Yerkes-D...
Emotional intensity produces a linear relationship on conditioned learning but an inverted U-shaped effect on episodic memory [0.03%]
情绪强度在条件学习中产生线性关系,但在情景记忆中呈现倒U形效应
Lingwei Ouyang,Joseph E Dunsmoor
Lingwei Ouyang
Emotional intensity can produce both optimal and suboptimal effects on learning and memory. While emotional events tend to be better remembered, memory performance can follow an inverted U-shaped curve with increasing intensity. The strengt...
Social and nonsocial environmental loss have differential effects on ventral hippocampus-dependent behavior and inhibitory synaptic markers in adult male mice [0.03%]
社会性和非社会性环境丧失对成年雄性小鼠腹侧海马依赖的行为和抑制性突触标志物具有不同的影响
Isha R Gore,Casey J Brown,Renée C Waters et al.
Isha R Gore et al.
In humans, psychological loss, whether social or nonsocial, can lead to clinical depression, anxiety disorders, and social memory impairments. Researchers have modeled combined social and nonsocial loss in rodents by transitioning them from...
Lateral entorhinal cortex neurons that project to nucleus accumbens mediate contextual associative memory [0.03%]
侧嗅皮质至伏隔核投射神经元参与情境联想记忆编码
Hayley M Kuhn,Luis Colon Serrano,Grace A Stys et al.
Hayley M Kuhn et al.
The lateral entorhinal cortex (LEC) contains glutamatergic projections that innervate the nucleus accumbens (NAc) and may be involved in the encoding of contextual associations with both positive and negative valences, such as those encount...
Hillary Schwarb,Michael Dulas,Neal Cohen
Hillary Schwarb
Binding of arbitrary information into distinct memory representations that can be used to guide behavior is a hallmark of relational memory. What is and is not bound into a memory representation and how those things influence the organizati...