Decoding Arc transcription: a live-cell study of stimulation patterns and transcriptional output [0.03%]
活细胞刺激模式和转录组输出的解码研究
Dong Wook Kim,Hyungseok C Moon,Byung Hun Lee et al.
Dong Wook Kim et al.
Activity-regulated cytoskeleton-associated protein (Arc) plays a crucial role in synaptic plasticity, a process integral to learning and memory. Arc transcription is induced within a few minutes of stimulation, making it a useful marker for...
Courteney T L Fisher,Gonzalo P Urcelay
Courteney T L Fisher
Safety signals reinforce instrumental avoidance behavior in nonhuman animals. However, there are no conclusive demonstrations of this phenomenon in humans. Using human participants in an avoidance task, Experiments 1-3 and 5 were conducted ...
Connecting self-report and instrumental behavior during incubation of food craving in humans [0.03%]
人类在食物渴望期间连接自我报告和工具行为的脑机制研究
Nicholas A Ruiz,Devlin Eckardt,Lisa A Briand et al.
Nicholas A Ruiz et al.
Incubation of craving is a phenomenon describing the intensification of craving for a reward over extended periods of abstinence from reinforcement. Animal models use instrumental markers of craving to reward cues to examine incubation, whi...
Network motifs exhibiting a differential response to spaced and massed inputs [0.03%]
表现间隔输入和群集输入不同反应的网络动机模型
Ashley Sreejan,Priyanka Saxena,Chetan J Gadgil
Ashley Sreejan
One characteristic of long-term memory is the existence of an inverted U-shaped response to increasing intervals between training sessions, and consequently, an optimal spacing that maximizes memory formation. Current models of this spacing...
Flexible decision-making is related to strategy learning, vicarious trial and error, and medial prefrontal rhythms during spatial set-shifting [0.03%]
灵活的决策与空间任务转换过程中的策略学习、间接尝试和错误以及前额叶脑电节律有关
Jesse T Miles,Ginger L Mullins,Sheri J Y Mizumori
Jesse T Miles
Flexible decision-making requires a balance between exploring features of an environment and exploiting prior knowledge. Behavioral flexibility is typically measured by how long it takes subjects to consistently make accurate choices after ...
Transient enhancement of stimulus-evoked activity in neocortex during sensory learning [0.03%]
感觉学习过程中皮层感觉诱发电位的暂时增强现象
Mo Zhu,Sandra J Kuhlman,Alison L Barth
Mo Zhu
Synaptic potentiation has been linked to learning in sensory cortex, but the connection between this potentiation and increased sensory-evoked neural activity is not clear. Here, we used longitudinal in vivo Ca2+ imaging in the barrel corte...
Multiple changes in connectivity between buccal ganglia mechanoafferents and motor neurons with different functions after learning that food is inedible in Aplysia [0.03%]
阿氏海兔在学习食物不可食之后，唇脑神经元与执行不同功能的运动神经元之间连接性的多次改变
Itay Hurwitz,Shlomit Tam,Jian Jing et al.
Itay Hurwitz et al.
Changes caused by learning that a food is inedible in Aplysia were examined for fast and slow synaptic connections from the buccal ganglia S1 cluster of mechanoafferents to five followers, in response to repeated stimulus trains. Learning a...
Repeated stimulation of feeding mechanoafferents in Aplysia generates responses consistent with the release of food [0.03%]
重复刺激海兔的摄食机械感受器会产生与释放食物一致的反应
Itay Hurwitz,Shlomit Tam,Jian Jing et al.
Itay Hurwitz et al.
How does repeated stimulation of mechanoafferents affect feeding motor neurons? Monosynaptic connections from a mechanoafferent population in the Aplysia buccal ganglia to five motor followers with different functions were examined during r...
Skewing information flow through pre- and postsynaptic plasticity in the mushroom bodies of Drosophila [0.03%]
通过果蝇蘑菇体中的突触前和突触后可塑性来调节信息流
Carlotta Pribbenow,David Owald
Carlotta Pribbenow
Animal brains need to store information to construct a representation of their environment. Knowledge of what happened in the past allows both vertebrates and invertebrates to predict future outcomes by recalling previous experience. Althou...
An integrative sensor of body states: how the mushroom body modulates behavior depending on physiological context [0.03%]
整合感觉器官：蘑菇体如何根据生理状况调节行为
Raquel Suárez-Grimalt,Ilona C Grunwald Kadow,Lisa Scheunemann
Raquel Suárez-Grimalt
The brain constantly compares past and present experiences to predict the future, thereby enabling instantaneous and future behavioral adjustments. Integration of external information with the animal's current internal needs and behavioral ...